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NCT07146438 · ClinicalTrials.gov registry record · NA
Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder
A NA study of Obsessive - Compulsive Disorder, sponsored by Adam Frank.
- Recruiting
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT07146438: Recruiting NA study of Obsessive - Compulsive Disorder, sponsored by Adam Frank.
NCT07146438 is a NA study of Obsessive - Compulsive Disorder that is actively recruiting participants, run by Adam Frank. The registered enrollment target is 48 participants, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07146438, a NA study of Obsessive - Compulsive Disorder, is actively recruiting participants, sponsored by Adam Frank.
- RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will test how people with OCD respond to a type of noninvasive brain stimulation, repetitive Transcranial Magnetic Stimulation (rTMS), when it is combined with psychotherapy. Participants will either engage in Exposure and Response Prevention (ERP) Therapy or supportive therapy (ST) while receiving rTMS. Biobehavioral data from wearable devices and smartphones will be collected to better predict treatment responses. Participants will also undergo repeat resting state functional Magnetic Resonance Imaging (rsfMRI) in order to assess neural predictors and mechanisms of treatment response.
Primary Outcome
The investigators will use the Yale-Brown Obsessive-Compulsive Scale (YBOCS), the gold standard measure of OCD severity, to assess symptom levels. The YBOCS scale assesses five domains of obsessive and compulsive symptoms, which are each scored on a four-point scale, with 0 being "no symptoms" and 4 being "extreme symptoms". Combined scores range from 0 (no symptoms) to 40 (severe symptoms). A trained clinician, blinded to participant treatment, will administer the YBOCS at study enrollment, wee
Conditions Studied
Interventions
- DEVICE Repetitive Transcranial Magnetic Stimulation (rTMS)
- BEHAVIORAL Supportive Therapy (ST)
- BEHAVIORAL Exposure and Response Prevention (ERP) Therapy
Study Locations (1)
California
- University of Southern California Health Sciences Campus - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2025-11-10 |
| Est. Completion | 2028-08 |
| Phase | NA |
What NCT07146438 shows while recruiting
NCT07146438 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 3 interventions - of which Repetitive Transcranial Magnetic Stimulation (rTMS) is the first listed.
NCT07146438 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT07146438 about?
NCT07146438 is a clinical study titled "Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder". This study will test how people with OCD respond to a type of noninvasive brain stimulation, repetitive Transcranial Magnetic Stimulation (rTMS), when it is combined with psychotherapy. Participants will either engage in Exposure and Response Prevention (ERP) Therapy or supportive therapy (ST) while...
What is the current status of trial NCT07146438?
This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2025-11-10. Estimated completion is 2028-08.
What conditions does trial NCT07146438 study?
This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.
What interventions are being tested in trial NCT07146438?
The interventions under investigation include: Repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE), Supportive Therapy (ST) (BEHAVIORAL), Exposure and Response Prevention (ERP) Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT07146438?
This trial is sponsored by Adam Frank, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07146438 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07146438's enrollment target sits among peer trials
48 44th of 84 higher than 40 of 84 other Obsessive - Compulsive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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