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NCT03826693 · ClinicalTrials.gov registry record · Phase 2

Efficacy of Nitrous Oxide in OCD: Pilot Study

A Phase 2 study of Obsessive - Compulsive Disorder, sponsored by Stanford University.

Recruiting
Registry status
Phase 2
Development phase
45
Enrollment target
1
Study location

NCT03826693: Recruiting Phase 2 study of Obsessive - Compulsive Disorder, sponsored by Stanford University.

NCT03826693 is a Phase 2 study of Obsessive - Compulsive Disorder that is actively recruiting participants, run by Stanford University. The registered enrollment target is 45 participants, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03826693, a Phase 2 study of Obsessive - Compulsive Disorder, is actively recruiting participants, sponsored by Stanford University.

RECRUITING
Registry status
Phase 2
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

This study investigates whether the commonly used and well-tolerated inhaled anesthetic nitrous oxide can rapidly improve symptoms of OCD.

Primary Outcome

Improvement in OCD severity is measured by the YBOCS (Yale Brown Obsessive-Compulsive Scale), a gold standard measure of obsessions and compulsions. For the YBOCS the minimum units are 0 and Maximum units on the total scale are 40. The higher the number on the YBOCS, the more severe the symptoms. Response is defined as at least a 35% reduction on the YBOCS.

Interventions

  • DRUG Nitrous Oxide
  • DRUG Nitrogen

Study Locations (1)

California

  • Stanford University - Stanford

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2021-04-17
Est. Completion 2027-10
Phase Phase 2
Stanford University

1,744 total trials

What NCT03826693 shows while recruiting

NCT03826693 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (98% lower).

The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 2 interventions - of which Nitrous Oxide is the first listed.

NCT03826693 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT03826693 about?

NCT03826693 is a clinical study titled "Efficacy of Nitrous Oxide in OCD: Pilot Study". This study investigates whether the commonly used and well-tolerated inhaled anesthetic nitrous oxide can rapidly improve symptoms of OCD.

What is the current status of trial NCT03826693?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2021-04-17. Estimated completion is 2027-10.

What conditions does trial NCT03826693 study?

This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.

What interventions are being tested in trial NCT03826693?

The interventions under investigation include: Nitrous Oxide (DRUG), Nitrogen (DRUG).

Who is sponsoring clinical trial NCT03826693?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03826693 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Obsessive - Compulsive Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03826693's enrollment target sits among peer trials

45 47th of 84 higher than 36 of 84 other Obsessive - Compulsive Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03826693, the US trial registry maintained by the National Library of Medicine. NCT03826693 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.