Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Alcohol Drinking

Open-data reference.

86 US clinical trials · 41 currently recruiting

Active & Recent Trials

RECRUITING 5,122 participants

The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Memorial Sloan Kettering Cancer Center

NCT06535867

RECRUITING NA 3,000 participants

Text-Based Messaging Strategies for Preventing Subsequent Problematic Alcohol Use

University of Virginia

NCT06318975

RECRUITING 1,500 participants

COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT04391816

RECRUITING NA 1,400 participants

Technology Interventions for Youth Alcohol Use

University of Michigan

NCT05988931

RECRUITING 1,000 participants

Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02108080

RECRUITING NA 744 participants

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

Stanford University

NCT05619185

RECRUITING NA 600 participants

Reducing Alcohol Exposed Pregnancies

New York University

NCT05766761

RECRUITING NA 504 participants

Drinking in Young Adult Duos (DYAD) Study

Carnegie Mellon University

NCT06822257

RECRUITING NA 464 participants

Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault

University of Washington

NCT06444295

RECRUITING NA 450 participants

Motivations, Attitudes, and Perceptions Study

University of Nebraska Lincoln

NCT05873413

RECRUITING NA 440 participants

Alcohol Screening and Preoperative Intervention Research Study - 2

University of Michigan

NCT05783635

RECRUITING NA 400 participants

Behavioral and Functional Task Development, Implementation, and Testing

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02108054

RECRUITING NA 400 participants

Just-In-Time Intervention to Reduce Alcohol-Facilitated Intimate Partner Violence Perpetration

Georgia State University

NCT05145868

RECRUITING NA 354 participants

Alcohol and "Heat of the Moment" Sexual Decision Making

Boston University Charles River Campus

NCT05729256

RECRUITING Phase 2 350 participants

Cannabis' Impact on Alcohol Consumption

Brown University

NCT05389930

RECRUITING NA 320 participants

Alcohol & Men's Sexual Risk Behaviors

Arizona State University

NCT06158880

RECRUITING NA 300 participants

Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers

Syracuse University

NCT06648629

RECRUITING NA 300 participants

Young Adult Education on Alcohol & Health

University of Washington

NCT05620849

RECRUITING NA 280 participants

Effects of Stereotype Threat on Impulsivity and Its Relation to Alcohol Use in African Americans: An fMRI Study

Icahn School of Medicine at Mount Sinai

NCT05675332

RECRUITING NA 255 participants

Journey of Transformation Curriculum for Native American Youth

University of Washington

NCT05731713

RECRUITING Phase 2 250 participants

Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

Vanderbilt University Medical Center

NCT05288790

RECRUITING 240 participants

Alcohol and the Social Brain: an Alcohol-Administration Hyperscanning Study

University of Illinois at Urbana-Champaign

NCT06687525

RECRUITING 240 participants

Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

University of Illinois at Urbana-Champaign

NCT05692830

RECRUITING NA 200 participants

Approach-Avoidance and Alcohol Challenge Study in PTSD

University of Texas at Austin

NCT06002633

RECRUITING NA 200 participants

Virtual Incentive Treatment for Alcohol

Washington State University

NCT06265506

RECRUITING NA 200 participants

ChangeGradients: Promoting Adolescent Health Behavior Change

University of California, San Francis

NCT04110756

RECRUITING NA 200 participants

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design

University of Illinois at Urbana-Champaign

NCT07125534

RECRUITING NA 160 participants

The Healthy Families Bright Futures Program

University of Colorado, Colorado Springs

NCT06309134

RECRUITING NA 136 participants

Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults

Kaiser Permanente

NCT05991882

RECRUITING Phase 1 128 participants

Nicotinic Receptor Genetic Variation and Alcohol Reward

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT03294460

RECRUITING Phase 1 100 participants

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Yale University

NCT06513819

RECRUITING NA 100 participants

Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study

University of Texas at Austin

NCT05838274

RECRUITING NA 90 participants

Multi-Component Breath Alcohol Intervention Phase 3

Northeastern University

NCT06994962

RECRUITING NA 86 participants

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

Medical University of South Carolina

NCT04998916

RECRUITING NA 62 participants

Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students

University of Wyoming

NCT07157124

RECRUITING NA 60 participants

Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents

University of Rhode Island

NCT05380765

RECRUITING NA 55 participants

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

The University of Texas at Arlington

NCT05522075

RECRUITING NA 20 participants

The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers

University of Miami

NCT07415707

RECRUITING Phase 2 20 participants

Ketone Ester Intervention in Alcohol Use Disorder

University of Pennsylvania

NCT04616781

RECRUITING Phase 2 20 participants

Effects Ketone Supplement and Alcohol on Brain Metabolism

University of Pennsylvania

NCT06815237

RECRUITING Phase 2 20 participants

Effect of Nutritional Ketosis on Alcohol Metabolism

University of Pennsylvania

NCT06065657

ACTIVE NOT RECRUITING NA 1,172 participants

WayToServePlus: Improving Responsible Alcohol Service Ph II

Klein Buendel

NCT05779774

ACTIVE NOT RECRUITING NA 830 participants

Brief Intervention for Alcohol Use Among Injured Patients

University of California, Davis

NCT00278785

ACTIVE NOT RECRUITING NA 806 participants

Digital Motivational Behavioral Economic Intervention to Reduce Risky Drinking Among Community-Dwelling Emerging Adults

University of Florida

NCT05443750

ACTIVE NOT RECRUITING Early Phase 1 782 participants

Behavioral Alcohol Responses (BAR) Study

Carnegie Mellon University

NCT03467191

ACTIVE NOT RECRUITING NA 600 participants

Using Telehealth to Address Alcohol Misuse in HIV Care

Brown University

NCT04546971

ACTIVE NOT RECRUITING NA 470 participants

TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study

University of New Mexi

NCT06074341

ACTIVE NOT RECRUITING NA 225 participants

A Brief Intervention for Alcohol Users With Interpersonal Trauma

Western Kentucky University

NCT05414344

ACTIVE NOT RECRUITING NA 152 participants

Alcohol Feedback, Reflection and Morning Evaluation

Brown University

NCT05509218

ACTIVE NOT RECRUITING NA 115 participants

Multi-Component Breath Alcohol Intervention

Northeastern University

NCT06124898

ACTIVE NOT RECRUITING NA 42 participants

Improving Care for Unhealthy Alcohol Use in Primary Care

VA Office of Research and Development

NCT04565899

ACTIVE NOT RECRUITING Phase 2 20 participants

Does Propranolol, a Beta Blocker, Attenuate Stress-Induced Drinking?

Yale University

NCT03588754

ACTIVE NOT RECRUITING Phase 2 10 participants

Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy Volunteers

University of Pennsylvania

NCT05551754

COMPLETED NA 13,680 participants

Screening and Management of Unhealthy Alcohol Use in Primary Care

Virginia Commonwealth University

NCT04248023

COMPLETED NA 7,034 participants

Impacts of Subsidized Ridesharing on Drunk Driving, Alcohol Consumption, and Mobility

Columbia University

NCT04949711

COMPLETED NA 1,268 participants

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

University of New Hampshire

NCT03488927

COMPLETED NA 1,053 participants

Evaluations of Alcohol Warning Labels

University of Connecticut

NCT06129487

COMPLETED NA 730 participants

ReDIAL: A Telephone Brief Intervention for Injured Emergency Department Patients

Rhode Island Hospital

NCT01326169

COMPLETED NA 679 participants

Evaluation of the Media Detective Program for Elementary School-Aged Children to Prevention Substance Use

Innovation Research & Training

NCT01060852

COMPLETED NA 591 participants

Using Counter Attitudinal Advocacy to Change Drinking Behavior

Brown University

NCT04042909

COMPLETED NA 344 participants

Implementing Mobile Technology for Unhealthy Alcohol Use

UConn Health

NCT05350878

COMPLETED NA 320 participants

Alcohol and Health: Personalized Feedback

Oklahoma State University

NCT03337438

COMPLETED NA 314 participants

Evaluation of PRYSHM for LGBTQIA2S+ Youth

University of Nebraska Lincoln

NCT05521906

COMPLETED NA 210 participants

Behavioral Interventions to Reduce Heavy Drinking Among MSM in HIV Primary Care

Brown University

NCT02709759

COMPLETED NA 169 participants

The Drinking Dashboard Study

University of Missouri-Columbia

NCT05630625

COMPLETED NA 164 participants

Adaptive Interventions for Problem Drinkers

Northwell Health

NCT02511808

COMPLETED NA 120 participants

Coping Skills for Alcohol Use

University of Washington

NCT05356533

COMPLETED NA 119 participants

Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation

Brown University

NCT03068611

COMPLETED NA 115 participants

Retraining Attention to Treat Alcohol Dependence and Social Anxiety

University of Cincinnati

NCT01886716

COMPLETED NA 100 participants

Alcohol Misuse Intervention in Active Duty US Navy Personnel

University of New Mexi

NCT04893044

COMPLETED NA 99 participants

Testing Brief Personalized Feedback Integrating EMA Alcohol Cue Information

University of Washington

NCT05373706

COMPLETED NA 76 participants

Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection

Brown University

NCT04050735

COMPLETED NA 60 participants

Reducing Alcohol Use Post-Bariatric Surgery

Henry Ford Health System

NCT04788316

COMPLETED NA 60 participants

Acute Alcohol Response In Bipolar Disorder: a fMRI Study

University of Texas at Austin

NCT04063384

COMPLETED Phase 2 57 participants

Neuroscience-Informed Treatment Development for Adolescent Alcohol Use

Medical University of South Carolina

NCT03238300

COMPLETED Phase 2 39 participants

Baclofen for Treating Anxiety and Alcoholism

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT01751386

COMPLETED NA 34 participants

Preventing Alcohol and Other Drug Use and Violence Among Latino Youth

Boston College

NCT05240313

COMPLETED Phase 1 27 participants

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

Northwell Health

NCT02885311

COMPLETED NA 25 participants

Acute Neuroimmune Effects of Alcohol Using Free Water Imaging

Brown University

NCT03370783

COMPLETED Phase 2 22 participants

Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 1: Nicotine Replacement Therapy

Yale University

NCT00699556

COMPLETED NA 22 participants

Evaluating Perceived Fitness to Drive While Intoxicated

University of Pennsylvania

NCT05028413

COMPLETED Phase 1 14 participants

A Novel Compound for Alcoholism Treatment

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02039349

COMPLETED Phase 1 13 participants

Opioid Modulation and Neural Reward Activation in Healthy Adults

University of Colorado, Denver

NCT04854551

COMPLETED NA 12 participants

The Effects of Alcohol Consumption on Central Adiposity

Pennington Biomedical Research Center

NCT03521817

COMPLETED Phase 1 11 participants

The Behavioral Effects of Opioids and Alcohol

Sharon Walsh

NCT04300751

COMPLETED NA 10 participants

Brief Interventions With Text Messaging to Reduce Adolescent Alcohol and Marijuana Use

Yale University

NCT03401333

Phase Distribution

PhaseTrial count
Early Phase 1 7
Phase 2 10

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Alcohol Drinking Trial Landscape

ClinicalTrials.gov lists 86 US studies indexed under Alcohol Drinking, and 41 of those are currently open to recruitment — roughly 48% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Alcohol Drinking shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 17 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Alcohol Drinking is led by Brown University with 8 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 86 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Alcohol Drinking?

PlainTrial tracks 86 US clinical trials for Alcohol Drinking, of which 41 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Alcohol Drinking?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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