Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Alcohol Drinking
Open-data reference.
86 US clinical trials · 41 currently recruiting
Active & Recent Trials
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Memorial Sloan Kettering Cancer Center
NCT06535867
Text-Based Messaging Strategies for Preventing Subsequent Problematic Alcohol Use
University of Virginia
NCT06318975
COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT04391816
Technology Interventions for Youth Alcohol Use
University of Michigan
NCT05988931
Characterization Imaging Instruments in Alcoholics and Non-Alcoholics
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02108080
A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
Stanford University
NCT05619185
Reducing Alcohol Exposed Pregnancies
New York University
NCT05766761
Drinking in Young Adult Duos (DYAD) Study
Carnegie Mellon University
NCT06822257
Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault
University of Washington
NCT06444295
Motivations, Attitudes, and Perceptions Study
University of Nebraska Lincoln
NCT05873413
Alcohol Screening and Preoperative Intervention Research Study - 2
University of Michigan
NCT05783635
Behavioral and Functional Task Development, Implementation, and Testing
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02108054
Just-In-Time Intervention to Reduce Alcohol-Facilitated Intimate Partner Violence Perpetration
Georgia State University
NCT05145868
Alcohol and "Heat of the Moment" Sexual Decision Making
Boston University Charles River Campus
NCT05729256
Cannabis' Impact on Alcohol Consumption
Brown University
NCT05389930
Alcohol & Men's Sexual Risk Behaviors
Arizona State University
NCT06158880
Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers
Syracuse University
NCT06648629
Young Adult Education on Alcohol & Health
University of Washington
NCT05620849
Effects of Stereotype Threat on Impulsivity and Its Relation to Alcohol Use in African Americans: An fMRI Study
Icahn School of Medicine at Mount Sinai
NCT05675332
Journey of Transformation Curriculum for Native American Youth
University of Washington
NCT05731713
Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT
Vanderbilt University Medical Center
NCT05288790
Alcohol and the Social Brain: an Alcohol-Administration Hyperscanning Study
University of Illinois at Urbana-Champaign
NCT06687525
Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms
University of Illinois at Urbana-Champaign
NCT05692830
Approach-Avoidance and Alcohol Challenge Study in PTSD
University of Texas at Austin
NCT06002633
Virtual Incentive Treatment for Alcohol
Washington State University
NCT06265506
ChangeGradients: Promoting Adolescent Health Behavior Change
University of California, San Francis
NCT04110756
Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design
University of Illinois at Urbana-Champaign
NCT07125534
The Healthy Families Bright Futures Program
University of Colorado, Colorado Springs
NCT06309134
Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults
Kaiser Permanente
NCT05991882
Nicotinic Receptor Genetic Variation and Alcohol Reward
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT03294460
HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)
Yale University
NCT06513819
Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study
University of Texas at Austin
NCT05838274
Multi-Component Breath Alcohol Intervention Phase 3
Northeastern University
NCT06994962
MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience
Medical University of South Carolina
NCT04998916
Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students
University of Wyoming
NCT07157124
Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents
University of Rhode Island
NCT05380765
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
The University of Texas at Arlington
NCT05522075
The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers
University of Miami
NCT07415707
Ketone Ester Intervention in Alcohol Use Disorder
University of Pennsylvania
NCT04616781
Effects Ketone Supplement and Alcohol on Brain Metabolism
University of Pennsylvania
NCT06815237
Effect of Nutritional Ketosis on Alcohol Metabolism
University of Pennsylvania
NCT06065657
WayToServePlus: Improving Responsible Alcohol Service Ph II
Klein Buendel
NCT05779774
Brief Intervention for Alcohol Use Among Injured Patients
University of California, Davis
NCT00278785
Digital Motivational Behavioral Economic Intervention to Reduce Risky Drinking Among Community-Dwelling Emerging Adults
University of Florida
NCT05443750
Behavioral Alcohol Responses (BAR) Study
Carnegie Mellon University
NCT03467191
Using Telehealth to Address Alcohol Misuse in HIV Care
Brown University
NCT04546971
TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study
University of New Mexi
NCT06074341
A Brief Intervention for Alcohol Users With Interpersonal Trauma
Western Kentucky University
NCT05414344
Alcohol Feedback, Reflection and Morning Evaluation
Brown University
NCT05509218
Multi-Component Breath Alcohol Intervention
Northeastern University
NCT06124898
Improving Care for Unhealthy Alcohol Use in Primary Care
VA Office of Research and Development
NCT04565899
Does Propranolol, a Beta Blocker, Attenuate Stress-Induced Drinking?
Yale University
NCT03588754
Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy Volunteers
University of Pennsylvania
NCT05551754
Screening and Management of Unhealthy Alcohol Use in Primary Care
Virginia Commonwealth University
NCT04248023
Impacts of Subsidized Ridesharing on Drunk Driving, Alcohol Consumption, and Mobility
Columbia University
NCT04949711
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
University of New Hampshire
NCT03488927
Evaluations of Alcohol Warning Labels
University of Connecticut
NCT06129487
ReDIAL: A Telephone Brief Intervention for Injured Emergency Department Patients
Rhode Island Hospital
NCT01326169
Evaluation of the Media Detective Program for Elementary School-Aged Children to Prevention Substance Use
Innovation Research & Training
NCT01060852
Using Counter Attitudinal Advocacy to Change Drinking Behavior
Brown University
NCT04042909
Implementing Mobile Technology for Unhealthy Alcohol Use
UConn Health
NCT05350878
Alcohol and Health: Personalized Feedback
Oklahoma State University
NCT03337438
Evaluation of PRYSHM for LGBTQIA2S+ Youth
University of Nebraska Lincoln
NCT05521906
Behavioral Interventions to Reduce Heavy Drinking Among MSM in HIV Primary Care
Brown University
NCT02709759
The Drinking Dashboard Study
University of Missouri-Columbia
NCT05630625
Adaptive Interventions for Problem Drinkers
Northwell Health
NCT02511808
Coping Skills for Alcohol Use
University of Washington
NCT05356533
Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation
Brown University
NCT03068611
Retraining Attention to Treat Alcohol Dependence and Social Anxiety
University of Cincinnati
NCT01886716
Alcohol Misuse Intervention in Active Duty US Navy Personnel
University of New Mexi
NCT04893044
Testing Brief Personalized Feedback Integrating EMA Alcohol Cue Information
University of Washington
NCT05373706
Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection
Brown University
NCT04050735
Reducing Alcohol Use Post-Bariatric Surgery
Henry Ford Health System
NCT04788316
Acute Alcohol Response In Bipolar Disorder: a fMRI Study
University of Texas at Austin
NCT04063384
Neuroscience-Informed Treatment Development for Adolescent Alcohol Use
Medical University of South Carolina
NCT03238300
Baclofen for Treating Anxiety and Alcoholism
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT01751386
Preventing Alcohol and Other Drug Use and Violence Among Latino Youth
Boston College
NCT05240313
Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home
Northwell Health
NCT02885311
Acute Neuroimmune Effects of Alcohol Using Free Water Imaging
Brown University
NCT03370783
Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 1: Nicotine Replacement Therapy
Yale University
NCT00699556
Evaluating Perceived Fitness to Drive While Intoxicated
University of Pennsylvania
NCT05028413
A Novel Compound for Alcoholism Treatment
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NCT02039349
Opioid Modulation and Neural Reward Activation in Healthy Adults
University of Colorado, Denver
NCT04854551
The Effects of Alcohol Consumption on Central Adiposity
Pennington Biomedical Research Center
NCT03521817
The Behavioral Effects of Opioids and Alcohol
Sharon Walsh
NCT04300751
Brief Interventions With Text Messaging to Reduce Adolescent Alcohol and Marijuana Use
Yale University
NCT03401333
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 7 |
| Phase 2 | 10 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Alcohol Drinking Trial Landscape
ClinicalTrials.gov lists 86 US studies indexed under Alcohol Drinking, and 41 of those are currently open to recruitment — roughly 48% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Alcohol Drinking shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 17 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Alcohol Drinking is led by Brown University with 8 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 86 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Alcohol Drinking?
PlainTrial tracks 86 US clinical trials for Alcohol Drinking, of which 41 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Alcohol Drinking?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.