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NCT05783817 · ClinicalTrials.gov registry record · Phase 2
MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)
A Phase 2 study of Obsessive - Compulsive Disorder, sponsored by Carolyn Rodriguez.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05783817: Recruiting Phase 2 study of Obsessive - Compulsive Disorder, sponsored by Carolyn Rodriguez.
NCT05783817 is a Phase 2 study of Obsessive - Compulsive Disorder that is actively recruiting participants, run by Carolyn Rodriguez. The registered enrollment target is 40 participants, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05783817, a Phase 2 study of Obsessive - Compulsive Disorder, is actively recruiting participants, sponsored by Carolyn Rodriguez.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The study assesses the safety and preliminary effectiveness of MDMA-assisted cognitive behavioral therapy in participants diagnosed with obsessive-compulsive disorder (OCD).
Primary Outcome
Change in OCD severity is measured by the YBOCS (Yale Brown Obsessive-Compulsive Scale), a gold standard measure of obsessions and compulsions. For the YBOCS the minimum units are 0 and Maximum units on the total scale are 40. The higher the number on the YBOCS, the more severe the symptoms. Response is defined as at least a 35% reduction on the YBOCS.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Behavioral Therapy (CBT)
- DRUG Methamphetamine
- DRUG 3,4-Methyl enedioxy methamphetamine
Study Locations (1)
California
- Stanford University Medical Center - Palo Alto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-09-10 |
| Est. Completion | 2026-12-01 |
| Phase | Phase 2 |
What NCT05783817 shows while recruiting
NCT05783817 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 2,064-participant average among 84 other Obsessive - Compulsive Disorder trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Obsessive - Compulsive Disorder appearing as the primary indexed condition, and to 3 interventions - of which Cognitive Behavioral Therapy (CBT) is the first listed.
NCT05783817 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05783817 about?
NCT05783817 is a clinical study titled "MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)". The study assesses the safety and preliminary effectiveness of MDMA-assisted cognitive behavioral therapy in participants diagnosed with obsessive-compulsive disorder (OCD).
What is the current status of trial NCT05783817?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2025-09-10. Estimated completion is 2026-12-01.
What conditions does trial NCT05783817 study?
This clinical trial studies the following conditions: Obsessive - Compulsive Disorder.
What interventions are being tested in trial NCT05783817?
The interventions under investigation include: Cognitive Behavioral Therapy (CBT) (BEHAVIORAL), Methamphetamine (DRUG), 3,4-Methyl enedioxy methamphetamine (DRUG).
Who is sponsoring clinical trial NCT05783817?
This trial is sponsored by Carolyn Rodriguez, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05783817 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obsessive - Compulsive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05783817's enrollment target sits among peer trials
40 50th of 84 higher than 33 of 84 other Obsessive - Compulsive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive - Compulsive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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