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NCT05467683 · ClinicalTrials.gov registry record · NA
CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
A NA study of Post Traumatic Stress Disorder and Obsessive - Compulsive Disorder, sponsored by University of Texas at Austin.
- Recruiting
- Registry status
- NA
- Development phase
- 600
- Enrollment target
- 2
- Study locations
NCT05467683: Recruiting NA study of Post Traumatic Stress Disorder and Obsessive - Compulsive Disorder, sponsored by University of Texas at Austin.
NCT05467683 is a NA study of Post Traumatic Stress Disorder and Obsessive - Compulsive Disorder that is actively recruiting participants, run by University of Texas at Austin. The registered enrollment target is 600 participants, roughly in line with the 662-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target. The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05467683, a NA study of Post Traumatic Stress Disorder and Obsessive - Compulsive Disorder, is actively recruiting participants, sponsored by University of Texas at Austin.
- RECRUITING
- Registry status
- NA
- Development phase
- 600 participants
- Enrollment target
- 2
- Study locations
Study Summary
Anxiety-, obsessive-compulsive and trauma- and stressor-related disorders reflect a significant public health problem. This study is designed to evaluate the predictive power of a novel biomarker based on a CO2 challenge, thus addressing the central question "can this easy-to-administer assay aid clinicians in deciding whether or not to initiate exposure-based therapy?"
Primary Outcome
Participants will be classified as non-responders if their Clinical Global Impression - Global Improvement (CGI-I) score is 3 or above OR if their Overall Anxiety Severity and Impairment Scale (OASIS) score has not improved by at least 4 points.
Conditions Studied
Interventions
- BEHAVIORAL Exposure-Based Therapy
Study Locations (2)
Massachusetts
- Boston University - Boston
Texas
- The University of Texas at Austin - Austin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2022-11-02 |
| Est. Completion | 2027-02-28 |
| Phase | NA |
What NCT05467683 shows while recruiting
NCT05467683 is an interventional study that assigns participants to a tested intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 662-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target.
The record links to 5 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 1 intervention - of which Exposure-Based Therapy is the first listed.
NCT05467683 reports a single indexed study location in Massachusetts, Texas.
Frequently Asked Questions
What is clinical trial NCT05467683 about?
NCT05467683 is a clinical study titled "CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy". Anxiety-, obsessive-compulsive and trauma- and stressor-related disorders reflect a significant public health problem. This study is designed to evaluate the predictive power of a novel biomarker based on a CO2 challenge, thus addressing the central question "can this easy-to-administer assay aid cl...
What is the current status of trial NCT05467683?
This trial is currently recruiting. It is a NA study. The enrollment target is 600 participants. The study started on 2022-11-02. Estimated completion is 2027-02-28.
What conditions does trial NCT05467683 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Obsessive - Compulsive Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder.
What interventions are being tested in trial NCT05467683?
The interventions under investigation include: Exposure-Based Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT05467683?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05467683 being conducted?
This trial has 2 study locations across Massachusetts, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Traumatic Stress Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05467683's enrollment target sits among peer trials
600 11th of 262 higher than 251 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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