Mclean Hospital

140 total trials 26 currently recruiting 92 completed

Mclean Hospital sponsors 140 registered US clinical trials on ClinicalTrials.gov, 26 of them currently recruiting, and 92 completed. 13 of these trials are in Phase 3-4 (later-stage) and 40 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Major Depressive Disorder, with 9 trials.

Trial Pipeline

140 total, page 1 of 3

RECRUITING Phase 1

A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder

NCT07460947

RECRUITING Early Phase 1

Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression

NCT07560878

RECRUITING

Identifying Substance Use Consequences

NCT07503067

RECRUITING NA

Stress Dynamics and Familial Risk for Depression in Female Adolescents

NCT06816329

RECRUITING Phase 1

Pharmacologic Augmentation of TMS for Depression With D-serine

NCT06876129

RECRUITING Phase 2

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation

NCT05232032

RECRUITING NA

Mechanisms of Exposure Therapy for OCD

NCT06173752

RECRUITING NA

Cerebellar Modulation of Cognition in Psychosis

NCT06107764

RECRUITING Phase 2

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

NCT06191965

RECRUITING NA

Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder

NCT06221852

RECRUITING Phase 2

Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis

NCT06477406

RECRUITING NA

Enhanced Coordinated Specialty Care for Early Psychosis

NCT06071858

RECRUITING Phase 2

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

NCT05837104

RECRUITING

Following Outcomes Remotely Within Addiction Recovery Domains

NCT06001437

RECRUITING NA

Role of Parent Interpretation Bias in the Transmission of Anxiety to Children

NCT05665491

RECRUITING Phase 2

Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder

NCT05457465

RECRUITING NA

Individually Targeted Neuromodulation for Contamination-based OCD

NCT05048251

RECRUITING

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

NCT05245903

RECRUITING NA

Interpretation Bias as a Mechanism of Treatment Response in OCD

NCT05224414

RECRUITING Early Phase 1

Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia

NCT04430517

RECRUITING

Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression

NCT05630963

RECRUITING NA

Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents

NCT04697966

RECRUITING NA

Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia

NCT05343598

RECRUITING NA

Neural Correlates of Stress and Perceived Control in Adolescent Depression

NCT04788524

RECRUITING

Early Life Stress and Depression: Molecular and Functional Imaging

NCT04713722

RECRUITING Early Phase 1

Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia

NCT04075435

ACTIVE NOT RECRUITING

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Study 1.2 (Stress Manipulation)

NCT04325529

ACTIVE NOT RECRUITING NA

Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression

NCT03484494

NOT YET RECRUITING NA

Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis

NCT07503093

NOT YET RECRUITING Phase 1

Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder

NCT07593222

COMPLETED Phase 4

Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenorrhea

NCT05900336

COMPLETED NA

Effectiveness of HabitWorks and Symptom Tracking for Anxiety and Depression

NCT07025486

COMPLETED NA

Women's Opioid Treatment Follow-up Study

NCT05776966

TERMINATED Phase 2

A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients

NCT05753007

COMPLETED NA

Psychoeducational Videos and Digital Assessments for BPD

NCT05358925

COMPLETED

Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale

NCT06152549

COMPLETED Phase 4

SMART Trial to Predict Anhedonia Response to Antidepressant Treatment

NCT05537584

COMPLETED NA

Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study

NCT05380583

TERMINATED NA

A Mobile Executive Functioning Intervention for Momentary Craving in Opioid Use Disorders

NCT05086835

TERMINATED NA

Effects of Attention Training Interventions on Depression

NCT04184206

COMPLETED

Detecting Drugs of Abuse Via Exhaled Breath Samples Using Differential Mobility Spectrometry

NCT05384470

COMPLETED NA

Pain, Inflammation and Opioid Craving

NCT04190563

TERMINATED Phase 2

A Clinical Trial of a Hemp-Derived Cannabidiol Product for Anxiety

NCT04286594

COMPLETED NA

Implementation of the Care Ecosystem Training Model for Individuals With Dementia in a High-risk, Integrated Care Management

NCT04556097

COMPLETED NA

Behavioral and Neural Phenotypes of Primary Dysmenorrhea in Adolescents

NCT04685343

COMPLETED NA

Families With Substance Use and Psychosis: A Pilot Study

NCT04284813

COMPLETED

Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression

NCT04239963

COMPLETED

Novel Cross-Species Neurophysiological Assays of Reward and Cognitive Domains

NCT02855229

TERMINATED Phase 1

Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression

NCT03999736

COMPLETED NA

Decision Making, Daily Experiences, and Brain Activity in Young Adult Women

NCT04125589

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Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 21
Phase 3 3
Phase 4 10

What the Pipeline for Mclean Hospital Shows

According to the ClinicalTrials.gov registry, Mclean Hospital is linked to 140 US clinical trials across every stage of research activity. Of those, 26 studies are currently recruiting, about 19% of the sponsor's indexed portfolio, and 92 are already marked complete, representing roughly 66% of the total.

The phase mix for Mclean Hospital reports 13 late-stage studies (Phase 3 and Phase 4 combined) and 40 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Mclean Hospital is Major Depressive Disorder with 9 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.