Mclean Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mclean Hospital sits in the top decile of US sponsors by registered trial count (#201 of 15,742 sponsors by registered trial count).
Mclean Hospital: 140 sponsored US clinical trials, 26 recruiting.
Mclean Hospital sponsors 140 registered US clinical trials on ClinicalTrials.gov, 26 of them currently recruiting, and 92 completed. 13 of these trials are in Phase 3-4 (later-stage) and 40 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Major Depressive Disorder, with 9 trials.
Top-decile sponsor footprint
Mclean Hospital ranks in the top decile of sponsors by registered trial count (#201 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
92 of 110 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
140 total, page 1 of 3
A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder
NCT07460947
Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression
NCT07560878
Identifying Substance Use Consequences
NCT07503067
Stress Dynamics and Familial Risk for Depression in Female Adolescents
NCT06816329
Pharmacologic Augmentation of TMS for Depression With D-serine
NCT06876129
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
NCT05232032
Mechanisms of Exposure Therapy for OCD
NCT06173752
Cerebellar Modulation of Cognition in Psychosis
NCT06107764
MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
NCT06191965
Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
NCT06221852
Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis
NCT06477406
Enhanced Coordinated Specialty Care for Early Psychosis
NCT06071858
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
NCT05837104
Following Outcomes Remotely Within Addiction Recovery Domains
NCT06001437
Role of Parent Interpretation Bias in the Transmission of Anxiety to Children
NCT05665491
Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder
NCT05457465
Individually Targeted Neuromodulation for Contamination-based OCD
NCT05048251
Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
NCT05245903
Interpretation Bias as a Mechanism of Treatment Response in OCD
NCT05224414
Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia
NCT04430517
Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression
NCT05630963
Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents
NCT04697966
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
NCT05343598
Neural Correlates of Stress and Perceived Control in Adolescent Depression
NCT04788524
Early Life Stress and Depression: Molecular and Functional Imaging
NCT04713722
Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia
NCT04075435
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Study 1.2 (Stress Manipulation)
NCT04325529
Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression
NCT03484494
Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis
NCT07503093
Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder
NCT07593222
Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenorrhea
NCT05900336
Effectiveness of HabitWorks and Symptom Tracking for Anxiety and Depression
NCT07025486
Women's Opioid Treatment Follow-up Study
NCT05776966
A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patients
NCT05753007
Psychoeducational Videos and Digital Assessments for BPD
NCT05358925
Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale
NCT06152549
SMART Trial to Predict Anhedonia Response to Antidepressant Treatment
NCT05537584
Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study
NCT05380583
A Mobile Executive Functioning Intervention for Momentary Craving in Opioid Use Disorders
NCT05086835
Effects of Attention Training Interventions on Depression
NCT04184206
Detecting Drugs of Abuse Via Exhaled Breath Samples Using Differential Mobility Spectrometry
NCT05384470
Pain, Inflammation and Opioid Craving
NCT04190563
A Clinical Trial of a Hemp-Derived Cannabidiol Product for Anxiety
NCT04286594
Implementation of the Care Ecosystem Training Model for Individuals With Dementia in a High-risk, Integrated Care Management
NCT04556097
Behavioral and Neural Phenotypes of Primary Dysmenorrhea in Adolescents
NCT04685343
Families With Substance Use and Psychosis: A Pilot Study
NCT04284813
Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression
NCT04239963
Novel Cross-Species Neurophysiological Assays of Reward and Cognitive Domains
NCT02855229
Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression
NCT03999736
Decision Making, Daily Experiences, and Brain Activity in Young Adult Women
NCT04125589
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 19 |
| Phase 2 | 21 |
| Phase 3 | 3 |
| Phase 4 | 10 |
Therapeutic Areas
What is open in the Mclean Hospital pipeline
26 recruiting of 140 indexed (19% open); 92 completed (66%).
Phase mix: 13 late (III/IV) vs 40 early (I/II) (early-phase heavy).
Top condition: Major Depressive Disorder (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Mclean Hospital: open-pipeline peers nationwide
Peers matched on 140 registered trials and 19% open enrollment, not the therapeutic-area sidebar.
Mclean Hospital sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 140 trials (± recruiting share)
- Case Western Reserve University · 141 trials · 16% recruiting
- Eastern Cooperative Oncology Group · 141 trials · 3% recruiting
- Purdue University · 141 trials · 10% recruiting
- Barbara Ann Karmanos Cancer Institute · 139 trials · 12% recruiting
Sponsors near 19% open enrollment (± trial volume)
- Children's Hospital Medical Center, Cincinnati · 19% recruiting · 571 trials
- Arkansas Children's Hospital Research Institute · 19% recruiting · 97 trials
- University of Missouri-Columbia · 19% recruiting · 291 trials
- Montefiore Medical Center · 19% recruiting · 345 trials
Related
What to do with this Mclean Hospital page
140 registered trials is a research-attention snapshot, not an endorsement of Mclean Hospital or any single study.
- 26 of Mclean Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Major Depressive Disorder is the condition Mclean Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Major Depressive Disorder trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Mclean Hospital pipeline card: 140 registered trials from official public datasets.Report a data error.