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NCT06953375 · ClinicalTrials.gov registry record · NA
Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty
A NA study of Aging and Total Knee Arthroplasty, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- NA
- Development phase
- 3,250
- Enrollment target
- 3
- Study locations
NCT06953375: Recruiting NA study of Aging and Total Knee Arthroplasty, sponsored by University of Colorado, Denver.
NCT06953375 is a NA study of Aging and Total Knee Arthroplasty that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 3,250 participants, above the 2,182-participant average among 262 other Aging trials with a reported enrollment target (49% higher). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06953375, a NA study of Aging and Total Knee Arthroplasty, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- NA
- Development phase
- 3,250 participants
- Enrollment target
- 3
- Study locations
Study Summary
Patients experience dramatic quadriceps strength loss after total knee replacement, which contributes to persistent weakness and reduced long-term function after surgery. Neuromuscular electrical stimulation (NMES) reduces quadriceps weakness and improves patient function after knee replacement, but it is drastically underused in rehabilitation practice. This randomized trial will examine the effectiveness and feasibility of a comprehensive strategy for implementing neuromuscular electrical stimulation after knee replacement in two large healthcare organizations.
Primary Outcome
The TUG is a measure of mobility and balance that consists of rising from a seated position, walking three meters, and pivoting and returning to the original seated position. Faster times indicate better physical function.
Conditions Studied
Interventions
- OTHER Usual Care
- PROCEDURE NMES
Study Locations (3)
Colorado
- UCHealth - Aurora
- University of Colorado Denver, Anschutz - Aurora
Utah
- Intermountain Health - Murray
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,250 participants |
| Start Date | 2025-05-12 |
| Est. Completion | 2029-04 |
| Phase | NA |
What NCT06953375 shows while recruiting
NCT06953375 is an interventional study that assigns participants to a tested intervention. Its 3,250 participants enrollment target places it among the larger protocols in the corpus, above the 2,182-participant average among 262 other Aging trials with a reported enrollment target (49% higher).
The record links to 4 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Usual Care is the first listed.
NCT06953375 reports a single indexed study location in Colorado, Utah.
Frequently Asked Questions
What is clinical trial NCT06953375 about?
NCT06953375 is a clinical study titled "Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty". Patients experience dramatic quadriceps strength loss after total knee replacement, which contributes to persistent weakness and reduced long-term function after surgery. Neuromuscular electrical stimulation (NMES) reduces quadriceps weakness and improves patient function after knee replacement, but...
What is the current status of trial NCT06953375?
This trial is currently recruiting. It is a NA study. The enrollment target is 3,250 participants. The study started on 2025-05-12. Estimated completion is 2029-04.
What conditions does trial NCT06953375 study?
This clinical trial studies the following conditions: Aging, Total Knee Arthroplasty, Physical Therapy, Functional Recovery.
What interventions are being tested in trial NCT06953375?
The interventions under investigation include: Usual Care (OTHER), NMES (PROCEDURE).
Who is sponsoring clinical trial NCT06953375?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06953375 being conducted?
This trial has 3 study locations across Colorado, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06953375's enrollment target sits among peer trials
3,250 6th of 262 higher than 257 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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