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NCT06645847 · ClinicalTrials.gov registry record · NA
Targeting Aging With a Ketone Ester for Function in Frailty
A NA study of Aging and Frail Elderly, sponsored by Buck Institute for Research on Aging.
- Recruiting
- Registry status
- NA
- Development phase
- 180
- Enrollment target
- 3
- Study locations
NCT06645847 is a NA study of Aging and Frail Elderly that is actively recruiting participants, run by Buck Institute for Research on Aging. The registered enrollment target is 180 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (92% lower). The trial reports 3 study locations across 3 states.
The verdict
NCT06645847, a NA study of Aging and Frail Elderly, is actively recruiting participants, sponsored by Buck Institute for Research on Aging.
- RECRUITING
- Registry status
- NA
- Development phase
- 180 participants
- Enrollment target
- 3
- Study locations
Study Summary
This study aims to find out if a food supplement that contains a naturally occurring substance, ketones, can help to improve strength and general wellness in adults at, or over the age of 65 years who are experiencing a slight decline in their physical function. Participation will involve a screening visit and 4 additional study visits over the course of 20 weeks. After being assessed for eligibility, study participants will be sorted into two groups at random and consume either a ketone or placebo supplement at home every day for 20 weeks. Both study products can cause gastro-intestinal side effects in some individuals. At all study visits, subjects will provide blood samples. At three study visits, subjects will be asked to complete physical performance tests, provide blood, stool and urine samples. They will also complete questionnaires during three study visits to assess physical function, markers of inflammation, and other aspects of general well-being. The study enrolls at three sites across the United States, in California (Buck Institute), Ohio (Ohio State University), and Connecticut (University of Connecticut). The study is coordinated by the San Francisco Coordinating Center (California Pacific Medical Center).
Conditions Studied
Interventions
- OTHER Ketone ester
- OTHER Placebo Comparator: Non-ketone placebo
Study Locations (3)
California
- Buck Institute for Research on Aging - Novato
Connecticut
- UConn Health - Farmington
Ohio
- Ohio State University - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2025-02-05 |
| Est. Completion | 2028-04-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06645847
The ClinicalTrials.gov registry entry for NCT06645847 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (92% lower). The listed sponsor is Buck Institute for Research on Aging, which has 5 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Ketone ester is the first listed.
NCT06645847 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Connecticut, Ohio.
Frequently Asked Questions
What is clinical trial NCT06645847 about?
NCT06645847 is a clinical study titled "Targeting Aging With a Ketone Ester for Function in Frailty". This study aims to find out if a food supplement that contains a naturally occurring substance, ketones, can help to improve strength and general wellness in adults at, or over the age of 65 years who are experiencing a slight decline in their physical function. Participation will involve a screeni...
What is the current status of trial NCT06645847?
This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2025-02-05. Estimated completion is 2028-04-01.
What conditions does trial NCT06645847 study?
This clinical trial studies the following conditions: Aging, Frail Elderly, Immune Function, Muscle Function.
What interventions are being tested in trial NCT06645847?
The interventions under investigation include: Ketone ester (OTHER), Placebo Comparator: Non-ketone placebo (OTHER).
Who is sponsoring clinical trial NCT06645847?
This trial is sponsored by Buck Institute for Research on Aging, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06645847 being conducted?
This trial has 3 study locations across California, Connecticut, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.