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NCT05266976 · ClinicalTrials.gov registry record · NA
Mode of Exercise and Bone Biomarkers in Older Veterans
A NA study of Aging and Osteoporosis, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT05266976: Recruiting NA study of Aging and Osteoporosis, sponsored by VA Office of Research and Development.
NCT05266976 is a NA study of Aging and Osteoporosis that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 120 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05266976, a NA study of Aging and Osteoporosis, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
Adults are often encouraged to exercise to maintain or improve bone health. However, there is evidence that exercise does not always lead to increases in bone mass, and exercise could lead to bone loss under certain conditions. Endurance exercise can increase bone resorption following an exercise bout, which may explain why bone does not always favorably adapt to exercise, but it is unclear if this also happens with resistance exercise. Further, it is not known how exercise training influences blood markers of bone resorption for either endurance or resistance exercise. The purpose of this study is to determine 1) if resistance exercise causes a similar increase in bone resorption as endurance exercise; and 2) if exercise training influences the increase in bone resorption following exercise for both endurance and resistance exercise.
Primary Outcome
CTX is a marker of bone resorption. Reference range is 0.1-0.8 ng/mL with lower concentrations suggesting less bone resorption
Conditions Studied
Interventions
- BEHAVIORAL 10 Weeks of Supervised Resistance Exercise Training
- BEHAVIORAL 10 Weeks of Supervised Endurance Exercise Training
Study Locations (1)
Colorado
- Rocky Mountain Regional VA Medical Center, Aurora, CO - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2022-07-06 |
| Est. Completion | 2027-03-31 |
| Phase | NA |
What NCT05266976 shows while recruiting
NCT05266976 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (95% lower).
The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which 10 Weeks of Supervised Resistance Exercise Training is the first listed.
NCT05266976 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT05266976 about?
NCT05266976 is a clinical study titled "Mode of Exercise and Bone Biomarkers in Older Veterans". Adults are often encouraged to exercise to maintain or improve bone health. However, there is evidence that exercise does not always lead to increases in bone mass, and exercise could lead to bone loss under certain conditions. Endurance exercise can increase bone resorption following an exercise bo...
What is the current status of trial NCT05266976?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2022-07-06. Estimated completion is 2027-03-31.
What conditions does trial NCT05266976 study?
This clinical trial studies the following conditions: Aging, Osteoporosis, Musculoskeletal Diseases.
What interventions are being tested in trial NCT05266976?
The interventions under investigation include: 10 Weeks of Supervised Resistance Exercise Training (BEHAVIORAL), 10 Weeks of Supervised Endurance Exercise Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT05266976?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05266976 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05266976's enrollment target sits among peer trials
120 70th of 262 higher than 188 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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