Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06397469 · ClinicalTrials.gov registry record · NA
Enhancing Attention and Wellbeing Using Digital Therapeutics
A NA study of Aging and Cognitive Decline, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- NA
- Development phase
- 4,000
- Enrollment target
- 1
- Study location
NCT06397469: Recruiting NA study of Aging and Cognitive Decline, sponsored by University of California, San Francisco.
NCT06397469 is a NA study of Aging and Cognitive Decline that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 4,000 participants, above the 2,179-participant average among 262 other Aging trials with a reported enrollment target (84% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06397469, a NA study of Aging and Cognitive Decline, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- NA
- Development phase
- 4,000 participants
- Enrollment target
- 1
- Study location
Study Summary
The goals of the proposed research are to first determine the minimal and/or optimal dose of a digital intervention required for cognitive enhancement, and then to examine the impact of several potential moderators of treatment effects (i.e., cognitive decline, AD polygenic hazard score, cardiovascular risk, and race/ethnicity). This knowledge gained from his high-impact study with transform the field of cognitive interventions, paving the way for a precision medicine model for cognitive enhancing interventions that improve quality of life for older adults and individuals with cognitive deficits at risk of developing dementia.
Primary Outcome
The CPT is a 23-minute task, where participants are instructed to respond to target stimuli (squares at the top of the screen) and withhold responses to non-target stimuli (squares at the bottom of the screen). Performance will be quantified as: (1) mean reaction times, (2) standard deviation of reaction times (RTV), and (3) d-prime (comparing correct target detections or 'hits' to incorrect non-target detections or 'false alarms').
Conditions Studied
Interventions
- DEVICE MediTrain
- DEVICE Worder
Study Locations (1)
California
- University of California San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,000 participants |
| Start Date | 2024-04-01 |
| Est. Completion | 2029-06 |
| Phase | NA |
What NCT06397469 shows while recruiting
NCT06397469 is an interventional study that assigns participants to a tested intervention. Its 4,000 participants enrollment target places it among the larger protocols in the corpus, above the 2,179-participant average among 262 other Aging trials with a reported enrollment target (84% higher).
The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which MediTrain is the first listed.
NCT06397469 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06397469 about?
NCT06397469 is a clinical study titled "Enhancing Attention and Wellbeing Using Digital Therapeutics". The goals of the proposed research are to first determine the minimal and/or optimal dose of a digital intervention required for cognitive enhancement, and then to examine the impact of several potential moderators of treatment effects (i.e., cognitive decline, AD polygenic hazard score, cardiovascu...
What is the current status of trial NCT06397469?
This trial is currently recruiting. It is a NA study. The enrollment target is 4,000 participants. The study started on 2024-04-01. Estimated completion is 2029-06.
What conditions does trial NCT06397469 study?
This clinical trial studies the following conditions: Aging, Cognitive Decline, MCI.
What interventions are being tested in trial NCT06397469?
The interventions under investigation include: MediTrain (DEVICE), Worder (DEVICE).
Who is sponsoring clinical trial NCT06397469?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06397469 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06397469's enrollment target sits among peer trials
4,000 5th of 262 higher than 258 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Ketone Ester And Salt (KEAS) in Older Adults
RECRUITING · NA
-
Using Nicotine to Reverse Age-related Auditory Processing Deficits
RECRUITING · NA
-
Heterogeneity of Vascular Adaptations to Exercise With Aging in Women and Men
RECRUITING · NA
-
Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging
RECRUITING · NA
-
Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults
RECRUITING · NA
-
The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00227253 · 4,000 participants
Chromosome 18 Clinical Research Center
- NCT00811148 · 4,000 participants
Florida Center for Brain Tumor Research
- NCT00897117 · 4,000 participants
Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer
- NCT00899301 · 4,000 participants
Collecting and Storing Tissue Samples From Women With or Without Breast Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI