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NCT03288220 · ClinicalTrials.gov registry record
Influence of Brain Oscillation-Dependent TMS on Motor Function
A clinical trial of Healthy and Stroke, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Recruiting
- Registry status
- 114
- Enrollment target
- 1
- Study location
NCT03288220: Recruiting study of Healthy and Stroke, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT03288220 is a study of Healthy and Stroke that is actively recruiting participants, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 114 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03288220, a study of Healthy and Stroke, is actively recruiting participants, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- RECRUITING
- Registry status
- 114 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands. But the effects of TMS are minor, and it doesn t work for everyone. Researchers want to study how to time brain stimulation so that the effects are more consistent. Objective: To understand how the brain responds to transcranial magnetic stimulation so that treatments for people with stroke can be improved. Eligibility: Adults ages 18 and older who had a stroke at least 6 months ago Healthy volunteers ages 50 and older Design: Participants will have up to 5 visits. At visit 1, participants will be screened with medical history and physical exam. Participants with stroke will also have TMS and surface electromyography (sEMG). For TMS, a brief electrical current will pass through a wire coil on the scalp. Participants may hear a click and feel a pull. Muscles may twitch. Participants may be asked to do simple movements during TMS. For sEMG, small electrodes will be attached to the skin and muscle activity will be recorded. At visit 2, participants will have magnetic resonance imaging (MRI). They will lie on a table that slides into a metal cylinder in a strong magnetic field. They will get earplugs for the loud noise. At visit 3, participants will have TMS, sEMG, and electroencephalography (EEG). For EEG, small electrodes on the scalp will record brainwaves. Participants will sit still, watch a movie, or do TMS. Participants may be asked to have 2 extra visits to redo procedures.
Primary Outcome
For both experiments, the primary outcome measure is corticospinal excitability. Exploratory outcome measures include MEP amplitude variability, and TMS-induced oscillations
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 114 participants |
| Start Date | 2018-09-11 |
| Est. Completion | 2029-03-31 |
What NCT03288220 shows while recruiting
NCT03288220 is an observational study that tracks outcomes without assigning an intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (82% lower).
The record links to 4 conditions, with Healthy appearing as the primary indexed condition, and to 0 interventions.
NCT03288220 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT03288220 about?
NCT03288220 is a clinical study titled "Influence of Brain Oscillation-Dependent TMS on Motor Function". Background: When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands. But the effects of TMS are minor, and it doesn t work for everyone. Researchers w...
What is the current status of trial NCT03288220?
This trial is currently recruiting. The enrollment target is 114 participants. The study started on 2018-09-11. Estimated completion is 2029-03-31.
What conditions does trial NCT03288220 study?
This clinical trial studies the following conditions: Healthy, Stroke, Aging, Normal Physiology.
Who is sponsoring clinical trial NCT03288220?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03288220 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03288220's enrollment target sits among peer trials
114 201st of 1090 higher than 890 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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