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NCT03372317 · ClinicalTrials.gov registry record

Tau PET in Imaging and Cognition: Healthy Adults From 55-90

A clinical trial of Aging and Mild Cognitive Impairment, sponsored by Yaakov Stern.

Recruiting
Registry status
105
Enrollment target
1
Study location

NCT03372317 is a study of Aging and Mild Cognitive Impairment that is actively recruiting participants, run by Yaakov Stern. The registered enrollment target is 105 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03372317, a study of Aging and Mild Cognitive Impairment, is actively recruiting participants, sponsored by Yaakov Stern.

RECRUITING
Registry status
105 participants
Enrollment target
1
Study location

Study Summary

The investigators aim to use the new PET radioligand, 18F-MK-6240, to detect tau pathology in cognitive healthy and mild cognitive impairment (MCI) elders. The investigators will then examine the interactions between differential tau burden and performance on cognitive tasks, functional magnetic resonance imaging (fMRI) neural activation patterns, and other cognitive and behavioral measures. By investigating these relationships, the investigators hope to understand the cognitive and behavioral outcomes of tau deposition found in specific brain regions in cognitively normal/mildly cognitively impaired adults. Furthermore, the study aims to examine how the presence of tau may contribute to the risk of subsequent cognitive decline, neurodegeneration, and dementia.

Interventions

  • DRUG 18F-MK-6240

Study Locations (1)

New York

  • Columbia University Medical Center - New York

Trial Details

FieldValue
Enrollment Target 105 participants
Start Date 2018-06-01
Est. Completion 2027-12

Sponsor

Yaakov Stern

2 total trials

What the Registry Record Tells You About NCT03372317

The ClinicalTrials.gov registry entry for NCT03372317 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (95% lower). The listed sponsor is Yaakov Stern, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Aging appearing as the primary indexed condition, and to 1 intervention - of which 18F-MK-6240 is the first listed.

NCT03372317 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT03372317 about?

NCT03372317 is a clinical study titled "Tau PET in Imaging and Cognition: Healthy Adults From 55-90". The investigators aim to use the new PET radioligand, 18F-MK-6240, to detect tau pathology in cognitive healthy and mild cognitive impairment (MCI) elders. The investigators will then examine the interactions between differential tau burden and performance on cognitive tasks, functional magnetic res...

What is the current status of trial NCT03372317?

This trial is currently recruiting. The enrollment target is 105 participants. The study started on 2018-06-01. Estimated completion is 2027-12.

What conditions does trial NCT03372317 study?

This clinical trial studies the following conditions: Aging, Mild Cognitive Impairment.

What interventions are being tested in trial NCT03372317?

The interventions under investigation include: 18F-MK-6240 (DRUG).

Who is sponsoring clinical trial NCT03372317?

This trial is sponsored by Yaakov Stern, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03372317 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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