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NCT03372317 · ClinicalTrials.gov registry record
Tau PET in Imaging and Cognition: Healthy Adults From 55-90
A clinical trial of Aging and Mild Cognitive Impairment, sponsored by Yaakov Stern.
- Recruiting
- Registry status
- 105
- Enrollment target
- 1
- Study location
NCT03372317: Recruiting study of Aging and Mild Cognitive Impairment, sponsored by Yaakov Stern.
NCT03372317 is a study of Aging and Mild Cognitive Impairment that is actively recruiting participants, run by Yaakov Stern. The registered enrollment target is 105 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03372317, a study of Aging and Mild Cognitive Impairment, is actively recruiting participants, sponsored by Yaakov Stern.
- RECRUITING
- Registry status
- 105 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators aim to use the new PET radioligand, 18F-MK-6240, to detect tau pathology in cognitive healthy and mild cognitive impairment (MCI) elders. The investigators will then examine the interactions between differential tau burden and performance on cognitive tasks, functional magnetic resonance imaging (fMRI) neural activation patterns, and other cognitive and behavioral measures. By investigating these relationships, the investigators hope to understand the cognitive and behavioral outcomes of tau deposition found in specific brain regions in cognitively normal/mildly cognitively impaired adults. Furthermore, the study aims to examine how the presence of tau may contribute to the risk of subsequent cognitive decline, neurodegeneration, and dementia.
Primary Outcome
Based on the scans, the total number of subjects with identifiable tau in their scans will be measured.
Conditions Studied
Interventions
- DRUG 18F-MK-6240
Study Locations (1)
New York
- Columbia University Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2018-06-01 |
| Est. Completion | 2027-12 |
What NCT03372317 shows while recruiting
NCT03372317 is an observational study that tracks outcomes without assigning an intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (95% lower).
The record links to 2 conditions, with Aging appearing as the primary indexed condition, and to 1 intervention - of which 18F-MK-6240 is the first listed.
NCT03372317 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT03372317 about?
NCT03372317 is a clinical study titled "Tau PET in Imaging and Cognition: Healthy Adults From 55-90". The investigators aim to use the new PET radioligand, 18F-MK-6240, to detect tau pathology in cognitive healthy and mild cognitive impairment (MCI) elders. The investigators will then examine the interactions between differential tau burden and performance on cognitive tasks, functional magnetic res...
What is the current status of trial NCT03372317?
This trial is currently recruiting. The enrollment target is 105 participants. The study started on 2018-06-01. Estimated completion is 2027-12.
What conditions does trial NCT03372317 study?
This clinical trial studies the following conditions: Aging, Mild Cognitive Impairment.
What interventions are being tested in trial NCT03372317?
The interventions under investigation include: 18F-MK-6240 (DRUG).
Who is sponsoring clinical trial NCT03372317?
This trial is sponsored by Yaakov Stern, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03372317 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03372317's enrollment target sits among peer trials
105 83rd of 262 higher than 179 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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