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NCT04911491 · ClinicalTrials.gov registry record · NA

Inspiratory Muscle Strength Training in Chronic Kidney Disease

A NA study of Hypertension and Aging, sponsored by University of Colorado, Denver.

Recruiting
Registry status
NA
Development phase
108
Enrollment target
1
Study location

NCT04911491 is a NA study of Hypertension and Aging that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 108 participants, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04911491, a NA study of Hypertension and Aging, is actively recruiting participants, sponsored by University of Colorado, Denver.

RECRUITING
Registry status
NA
Development phase
108 participants
Enrollment target
1
Study location

Study Summary

More than 80% of individuals with chronic kidney disease have concomitant hypertension and the majority fail to achieve blood pressure control \<130/80 mmHg, leading to high risk of cardiovascular diseases and end-stage kidney disease. A stepwise combination of lifestyle modifications and drug therapy is recommended to lower blood pressure; however, adherence to time-intensive lifestyle interventions such as aerobic exercise in patients with chronic kidney disease is poor. This clinical trial seeks to establish the efficacy of high-resistance inspiratory muscle strength training, a novel time-efficient lifestyle intervention, for lowering systolic blood pressure and improving endothelial function in midlife and older adults with moderate-to-severe chronic kidney disease and inadequately controlled hypertension, and to use innovate translational assessments to understand the mechanisms involved.

Interventions

  • DEVICE Sham Training
  • DEVICE IMST

Study Locations (1)

Colorado

  • University of Colorado - Anschutz Medical Campus - Aurora

Trial Details

FieldValue
Enrollment Target 108 participants
Start Date 2022-03-01
Est. Completion 2026-07-01
Phase NA

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT04911491

The ClinicalTrials.gov registry entry for NCT04911491 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 108 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,507-participant average among 470 other Hypertension trials with a reported enrollment target (97% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Sham Training is the first listed.

NCT04911491 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.

Frequently Asked Questions

What is clinical trial NCT04911491 about?

NCT04911491 is a clinical study titled "Inspiratory Muscle Strength Training in Chronic Kidney Disease". More than 80% of individuals with chronic kidney disease have concomitant hypertension and the majority fail to achieve blood pressure control \<130/80 mmHg, leading to high risk of cardiovascular diseases and end-stage kidney disease. A stepwise combination of lifestyle modifications and drug thera...

What is the current status of trial NCT04911491?

This trial is currently recruiting. It is a NA study. The enrollment target is 108 participants. The study started on 2022-03-01. Estimated completion is 2026-07-01.

What conditions does trial NCT04911491 study?

This clinical trial studies the following conditions: Hypertension, Aging, Blood Pressure, Chronic Kidney Diseases.

What interventions are being tested in trial NCT04911491?

The interventions under investigation include: Sham Training (DEVICE), IMST (DEVICE).

Who is sponsoring clinical trial NCT04911491?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04911491 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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