The Cleveland Clinic
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Trial Pipeline
688 total, page 3 of 14
Continuous Glucose Monitoring in Polycystic Ovarian Syndrome
NCT07392476
Sequential or CombinaTion Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)
NCT06854614
Shifting Options Study
NCT07225595
Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance
NCT07568275
Physiological Effects Ketone Ester in Heart
NCT05924802
Microbial Metabolites and Outcomes of Pregnancy Study
NCT06362356
3D Holographic Guidance, Navigation, and Control for Endovascular Aortic Repair
NCT06008613
Abdominal Wall Tension in Patients Undergoing Ventral Hernia Repair Without Component Separation
NCT06051578
VIRtual Versus UsuAL In-office Care for Multiple Sclerosis (VIRTUAL-MS)
NCT05660187
Glycemic Control, Type II Diabetes, Parathyroidectomy
NCT05761743
The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head
NCT05706909
Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia
NCT05568654
Impact of Surgical Coaching on Resident ObGyn Laparoscopic Skills
NCT05911165
Randomized Controlled Trial of Digital Twin Precision Treatment: A Novel Whole Body Digital Twin Enabled Precision Treatment for Type 2 Diabetes
NCT05181449
Variation in Humeral Head Bone Marrow Characteristics With Rotator Cuff Repair Healing
NCT05106088
CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)
NCT04748861
Low Tidal Volume Ventilation With Hyperoxia Avoidance During Cardiopulmonary Bypass (The FOCUS Trial)
NCT04978636
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
NCT03776162
Corticosteroid Meniscectomy Randomized Trial
NCT04641351
Operating Room Air Filtration/Sterilization
NCT04610294
Virtual and Video Counseling Versus In-Office Counseling for Laparoscopic Hysterectomy
NCT05086406
Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease
NCT04827368
Consumption of Oral Artificial Sweeteners on Platelet Aggregation and Polyol Excretion
NCT04731363
Analysis of MicroBial Metabolites After Eating Refined Food
NCT04308473
RHYTHMIA vs CARTO in Redo Ablation Procedures for Atrial Fibrillation
NCT04835844
CASE 1320: RAI Uptake and Serum Prolactin in Thyroid Cancer
NCT04495985
Central Vein Sign: a Diagnostic Biomarker in Multiple Sclerosis
NCT04495556
Oral Sodium to Preserve Renal EfficiencY in Acute Heart Failure
NCT04334668
Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis
NCT04687475
Preoperative Tamsulosin to Prevent Postoperative Urinary Retention After Surgery For Pelvic Floor Disorders
NCT04232683
Perioperative Lidocaine and Ketamine in Abdominal Surgery
NCT04084548
Imaging Quantification of Inflammation (IQI)
NCT04704609
Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS
NCT03535298
Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE)
NCT03288025
Quantitative MRI for Non-invasive Assessment of Severity of Alcoholic Liver Disease (ALD)
NCT03113929
Pulmonary Vascular Disease Phenomics Program PVDOMICS
NCT02980887
Rotator Cuff Failure With Continuity
NCT02716441
Uterine Transplantation for the Treatment of Uterine Factor Infertility
NCT02573415
Airway Redox and Gender Determinants in Severe Asthma
NCT01759186
CARNIVAL Study: Gut Flora Dependent Metabolism of Dietary CARNItine and Phosphatidylcholine and cardioVAscuLar Disease
NCT01731236
Cleveland Heart and Metabolic Prevention Study
NCT03012022
Identification of Genetic, Biochemical and Hormonal Factors Contributing to Atrial Fibrillation
NCT00599118
Shape-sensing Versus Electromagnetic Robotic Bronchoscopy for Evaluation of PulmoNary LEsions
NCT07411989
Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial
NCT07628192
Imaging in Semaglutide Study
NCT07695454
Clinical Decision Support Tool for the Treatment of Uncontrolled Hypertension
NCT07218198
Self-Start Triage Model for Post-Botox® Lower Urinary Tract Symptoms
NCT07648290
Neural Correlates of Suicidal Behavior in Youth
NCT07568054
Bone Marrow Aspirate Concentrate Versus Triamcinolone Injection For Hip Osteoarthritis
NCT04990128
Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator
NCT06426407
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What the Pipeline for The Cleveland Clinic Shows
According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.
The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.