The Cleveland Clinic
Open enrollment across a mixed-phase pipeline
According to ClinicalTrials.gov-derived indexes, The Cleveland Clinic sits in the top decile of US sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count).
The Cleveland Clinic: 688 sponsored US clinical trials, 99 recruiting.
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Top-decile sponsor footprint
The Cleveland Clinic ranks in the top decile of sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
437 of 539 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
688 total, page 3 of 14
Continuous Glucose Monitoring in Polycystic Ovarian Syndrome
NCT07392476
Sequential or CombinaTion Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)
NCT06854614
Shifting Options Study
NCT07225595
Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance
NCT07568275
Physiological Effects Ketone Ester in Heart
NCT05924802
Microbial Metabolites and Outcomes of Pregnancy Study
NCT06362356
3D Holographic Guidance, Navigation, and Control for Endovascular Aortic Repair
NCT06008613
Abdominal Wall Tension in Patients Undergoing Ventral Hernia Repair Without Component Separation
NCT06051578
VIRtual Versus UsuAL In-office Care for Multiple Sclerosis (VIRTUAL-MS)
NCT05660187
Glycemic Control, Type II Diabetes, Parathyroidectomy
NCT05761743
The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head
NCT05706909
Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia
NCT05568654
Impact of Surgical Coaching on Resident ObGyn Laparoscopic Skills
NCT05911165
Randomized Controlled Trial of Digital Twin Precision Treatment: A Novel Whole Body Digital Twin Enabled Precision Treatment for Type 2 Diabetes
NCT05181449
Variation in Humeral Head Bone Marrow Characteristics With Rotator Cuff Repair Healing
NCT05106088
CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)
NCT04748861
Low Tidal Volume Ventilation With Hyperoxia Avoidance During Cardiopulmonary Bypass (The FOCUS Trial)
NCT04978636
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
NCT03776162
Corticosteroid Meniscectomy Randomized Trial
NCT04641351
Operating Room Air Filtration/Sterilization
NCT04610294
Virtual and Video Counseling Versus In-Office Counseling for Laparoscopic Hysterectomy
NCT05086406
Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease
NCT04827368
Consumption of Oral Artificial Sweeteners on Platelet Aggregation and Polyol Excretion
NCT04731363
Analysis of MicroBial Metabolites After Eating Refined Food
NCT04308473
RHYTHMIA vs CARTO in Redo Ablation Procedures for Atrial Fibrillation
NCT04835844
CASE 1320: RAI Uptake and Serum Prolactin in Thyroid Cancer
NCT04495985
Central Vein Sign: a Diagnostic Biomarker in Multiple Sclerosis
NCT04495556
Oral Sodium to Preserve Renal EfficiencY in Acute Heart Failure
NCT04334668
Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis
NCT04687475
Preoperative Tamsulosin to Prevent Postoperative Urinary Retention After Surgery For Pelvic Floor Disorders
NCT04232683
Perioperative Lidocaine and Ketamine in Abdominal Surgery
NCT04084548
Imaging Quantification of Inflammation (IQI)
NCT04704609
Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS
NCT03535298
Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE)
NCT03288025
Quantitative MRI for Non-invasive Assessment of Severity of Alcoholic Liver Disease (ALD)
NCT03113929
Pulmonary Vascular Disease Phenomics Program PVDOMICS
NCT02980887
Rotator Cuff Failure With Continuity
NCT02716441
Uterine Transplantation for the Treatment of Uterine Factor Infertility
NCT02573415
Airway Redox and Gender Determinants in Severe Asthma
NCT01759186
CARNIVAL Study: Gut Flora Dependent Metabolism of Dietary CARNItine and Phosphatidylcholine and cardioVAscuLar Disease
NCT01731236
Cleveland Heart and Metabolic Prevention Study
NCT03012022
Identification of Genetic, Biochemical and Hormonal Factors Contributing to Atrial Fibrillation
NCT00599118
Shape-sensing Versus Electromagnetic Robotic Bronchoscopy for Evaluation of PulmoNary LEsions
NCT07411989
Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial
NCT07628192
Imaging in Semaglutide Study
NCT07695454
Clinical Decision Support Tool for the Treatment of Uncontrolled Hypertension
NCT07218198
Self-Start Triage Model for Post-Botox® Lower Urinary Tract Symptoms
NCT07648290
Neural Correlates of Suicidal Behavior in Youth
NCT07568054
Bone Marrow Aspirate Concentrate Versus Triamcinolone Injection For Hip Osteoarthritis
NCT04990128
Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator
NCT06426407
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What is open in the The Cleveland Clinic pipeline
99 recruiting of 688 indexed (14% open); 437 completed (64%).
Phase mix: 81 late (III/IV) vs 76 early (I/II) (balanced across stages).
Top condition: Atrial Fibrillation (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
The Cleveland Clinic: open-pipeline peers nationwide
Peers matched on 688 registered trials and 14% open enrollment, not the therapeutic-area sidebar.
The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 688 trials (± recruiting share)
- Vanderbilt University Medical Center · 677 trials · 19% recruiting
- Weill Medical College of Cornell University · 701 trials · 18% recruiting
- Icahn School of Medicine at Mount Sinai · 708 trials · 23% recruiting
- Sanofi · 713 trials · 10% recruiting
Sponsors near 14% open enrollment (± trial volume)
- Dana-Farber Cancer Institute · 14% recruiting · 781 trials
- ModernaTX · 14% recruiting · 90 trials
- Masonic Cancer Center, University of Minnesota · 14% recruiting · 249 trials
- Academic and Community Cancer Research United · 14% recruiting · 42 trials
Related
What to do with this The Cleveland Clinic page
688 registered trials is a research-attention snapshot, not an endorsement of The Cleveland Clinic or any single study.
- 99 of The Cleveland Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Atrial Fibrillation is the condition The Cleveland Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. The Cleveland Clinic pipeline card: 688 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.