The Cleveland Clinic

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, The Cleveland Clinic sits in the top decile of US sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count).

688 total trials 99 currently recruiting 437 completed top decile by trial count

The Cleveland Clinic: 688 sponsored US clinical trials, 99 recruiting.

The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.

Top-decile sponsor footprint

The Cleveland Clinic ranks in the top decile of sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 42/100

437 of 539 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

688 total, page 4 of 14

TERMINATED NA

A Multi-Disciplinary Technology-Based Care for Diabetic Ketoacidosis in Patients With Type 1 Diabetes

NCT06471322

COMPLETED NA

Accuracy of the Dexcom G7 Continuous Glucose Monitoring System Following Cardiac Surgery

NCT06338748

COMPLETED NA

Efficacy of Radiofrequency Micro Needling for the Treatment of Melasma in Skin of Color.

NCT06616311

TERMINATED

The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure

NCT06575166

COMPLETED Phase 4

Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy

NCT06533527

COMPLETED NA

Yoga for a Healthy Heart

NCT06155240

COMPLETED NA

Heat Loss in Humans Covered With Full-Body Blankets Connected to Different Warming Devices

NCT06198959

COMPLETED

Continuous Ward Monitoring With the GE Portrait Mobile Monitoring Solution: the COSMOS Trial

NCT06133140

COMPLETED

Continuous Glucose Monitoring for Post-kidney Transplantation in Pre-existing Type 2 Diabetes

NCT07271433

COMPLETED

Testing the Effectiveness of WW Clinic GLP1

NCT06034457

TERMINATED NA

Ethibond Suture vs Vessel Loop as Draining Seton for Complex Anal Fistulas

NCT05933343

COMPLETED Phase 4

Postoperative Urinary Retention in Patients After Noncardiac Surgery and Reversal of Neuromuscular Block

NCT05545280

COMPLETED NA

Identifying the Neural Signature of Exercise to Advance Treatment of PD Cognitive Declines

NCT05972759

TERMINATED

BAriatric Surgery Induced Chromosomal Change

NCT05903521

COMPLETED

Aldosterone Renin Ratio (ARR) Test to Increase Case-detection of Primary Aldosteronism (PA)

NCT05757076

COMPLETED

ZYNEX Cardiac Monitor in Patients Having Noncardiac Surgery

NCT05536258

COMPLETED Phase 4

Effect of Knee Pain on Walking Biomechanics

NCT05670236

COMPLETED NA

Virtual Visits for Postoperative Care Following Urogynecologic Surgery

NCT05641077

TERMINATED

IV Dislodgement Comparative Effectiveness Study

NCT05602285

COMPLETED Phase 4

Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection

NCT05719285

COMPLETED NA

External vs Internal-triggered Augmented-reality Visual Cues to Treat Freezing of Gait

NCT05608915

COMPLETED NA

Home Blood Pressure Monitoring to Improve Hypertension

NCT05604040

COMPLETED NA

A Pilot Study Swiftsure

NCT05578599

TERMINATED NA

Fascial Defect Closure for Minimally Invasive Parastomal Hernia Repair

NCT05514600

COMPLETED

The Prevalence of Autoimmune Antibodies in Patients with Type 2 Diabetes Managed by Endocrinology Vs. Primary Care

NCT05553145

COMPLETED

The COSMOS Trial. A Pilot Study A Pilot Study

NCT05280574

COMPLETED

Utilizing Neural Signatures and Virtual Reality to Advance DBS Programming

NCT05103384

COMPLETED

Object Assessment of Improvement in Non-Specific Symptoms After Parathyroidectomy for Primary Hyperparathyroidism

NCT06337825

COMPLETED

A Comparison of Serum and Urine N-telopeptide Marker

NCT05326815

COMPLETED NA

Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery

NCT05374096

COMPLETED NA

Standard vs Mini-PCNL for the Treatment of Stone Disease

NCT04069013

TERMINATED

Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain

NCT05386693

COMPLETED Early Phase 1

A Novel Brain Stimulation for Bimanual Motor Function and Control in Chronic Stroke

NCT05381740

COMPLETED

Physiologic Tension of the Abdominal Wall

NCT05163184

COMPLETED NA

Does an Abdominal Wall Nerve Block During Surgery Help Reduce Pain From Kidney Transplantation?

NCT05280197

COMPLETED Phase 4

Pectoralis and Serratus Muscle Blocks

NCT03743194

COMPLETED NA

SQ53 Disinfectant Wipes for Prevention of CRBSI

NCT04822467

COMPLETED Phase 4

Intravenous Oliceridine and Opioid-related Complications

NCT04979247

COMPLETED NA

Impact of Home Weight Tele-monitoring on the Number of Office Visits in the First Six Weeks of Life in Infants.

NCT04985227

COMPLETED NA

Preoperative Education

NCT04970069

COMPLETED NA

The Therapeutic Effects of Forced Aerobic Exercise in Multiple Sclerosis

NCT04906057

COMPLETED NA

Motivational Enhancement - Acute Decompensated Heart Failure and OSA

NCT04752462

COMPLETED NA

Accuracy of the Dexcom G6 Continuous Glucose Monitoring System Following Cardiac Surgery

NCT04569240

COMPLETED Phase 2

Supplements, Placebo, or Rosuvastatin Study

NCT04846231

TERMINATED NA

Vaginal Hysterectomy vs Supracervical Hysterectomy at the Time of Sacrocolpopexy

NCT04797585

TERMINATED NA

Clinical and Urgent Colonoscopy Outcomes Using the Pure-Vu® Cleansing System

NCT04729946

COMPLETED NA

Endotracheal Intubation Using Videolaryngoscopy Versus Conventional Direct Laryngoscopy

NCT04701762

COMPLETED NA

Application Based Addiction Treatment Adherence Trial

NCT04680741

TERMINATED NA

Patient Satisfaction With Virtual Visits

NCT04855708

COMPLETED Phase 4

Transition From Basal/Bolus to Once-weekly Subcutaneous Semaglutide and Basal Insulin in Patients With T2D

NCT04538352

← Previous Page 4 of 14 Next →

Phase Distribution

PhaseTrial count
Phase 1 38
Phase 2 38
Phase 3 22
Phase 4 59

What is open in the The Cleveland Clinic pipeline

99 recruiting of 688 indexed (14% open); 437 completed (64%).

Phase mix: 81 late (III/IV) vs 76 early (I/II) (balanced across stages).

Top condition: Atrial Fibrillation (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

The Cleveland Clinic: open-pipeline peers nationwide

Peers matched on 688 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 5%10%15%20%25% Total trials Recruiting share The Cleveland ClinicVanderbilt University Medical CenterWeill Medical College of Cornell UniversityIcahn School of Medicine at Mount SinaiSanofiDana-Farber Cancer InstituteModernaTXMasonic Cancer Center, University of MinnesotaAcademic and Community Cancer Research United
The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 688 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this The Cleveland Clinic page

688 registered trials is a research-attention snapshot, not an endorsement of The Cleveland Clinic or any single study.

  • 99 of The Cleveland Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Atrial Fibrillation is the condition The Cleveland Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. The Cleveland Clinic pipeline card: 688 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.