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NCT06426407 · ClinicalTrials.gov registry record
Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator
A clinical trial, sponsored by The Cleveland Clinic.
- Terminated
- Registry status
- 2
- Enrollment target
NCT06426407 is a clinical trial that was terminated before completion, run by The Cleveland Clinic. The registered enrollment target is 2 participants.
The verdict
NCT06426407 was terminated before completion, sponsored by The Cleveland Clinic.
- TERMINATED
- Registry status
- 2 participants
- Enrollment target
Study Summary
The goal of this observational study is to learn about blood pressure response to the vasopressor drug vasopressin in people with septic shock. The main questions it aims to answer are: * Are the levels of molecules showing communication between cells different between people whose blood pressure improves and people whose blood pressure does not improve when given a vasopressor medication? * Are measurements found on echocardiography (heart ultrasound) different between people whose blood pressure improves and people whose blood pressure does not improve when given a vasopressor medication? * Are measurements of blood oxygen in tissues just below the skin different between people whose blood pressure improves and people whose blood pressure does not improve when given a vasopressor medication? Participants will be asked to contribute one or two blood samples. Participants who are ordered the drug vasopressin will contribute two blood samples. Both samples will be about two tablespoons for a total of about four tablespoons. One sample will be drawn before starting vasopressin infusion and the second sample will be drawn between one and six hours after starting the vasopressor drug infusion. At the same time points, advanced echocardiography pictures and measurements of oxygen in tissues from a sensor placed on one of the hands will be taken. Participants who are not ordered the drug vasopressin and only ordered the drug norepinephrine will contribute only one blood sample. At the time the sample is collected, advanced echocardiography pictures and measurements of oxygen in tissues from a sensor placed on one of the hands will be taken. This research also involves analyzing data obtained during the participant's hospital stay.
Interventions
- DRUG Vasopressin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2026-02-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06426407
The ClinicalTrials.gov registry entry for NCT06426407 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Vasopressin is the first listed.
NCT06426407 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06426407 about?
NCT06426407 is a clinical study titled "Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator". The goal of this observational study is to learn about blood pressure response to the vasopressor drug vasopressin in people with septic shock. The main questions it aims to answer are: * Are the levels of molecules showing communication between cells different between people whose blood pressure ...
What is the current status of trial NCT06426407?
This trial is currently terminated. The enrollment target is 2 participants. The study started on 2025-10-01. Estimated completion is 2026-02-01.
What interventions are being tested in trial NCT06426407?
The interventions under investigation include: Vasopressin (DRUG).
Who is sponsoring clinical trial NCT06426407?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
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