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NCT07568054 · ClinicalTrials.gov registry record · NA
Neural Correlates of Suicidal Behavior in Youth
A NA study, sponsored by The Cleveland Clinic.
- Not yet
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT07568054 is a NA study that has not yet begun recruiting, run by The Cleveland Clinic. The registered enrollment target is 60 participants.
The verdict
NCT07568054, a NA study, has not yet begun recruiting, sponsored by The Cleveland Clinic.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
This study, titled "Neural Correlates of Suicidal Behavior in Youth: a Pre and Post CAMS Therapy Neuroimaging Study," aims to better understand the brain mechanisms underlying suicidal thoughts and behaviors in adolescents and young adults (ages 14-24). Suicide is a leading cause of death in this population, and current clinical approaches often fail to accurately predict or prevent suicidal behavior. This study seeks to identify objective neurobiological markers associated with suicide risk and treatment response. Participants will be divided into three groups: (1) high-risk individuals recently hospitalized following a suicide attempt, (2) medium-risk individuals with chronic suicidal ideation but no attempts, and (3) low-risk healthy controls. All participants will undergo advanced neuroimaging, including magnetoencephalography (MEG) and magnetic resonance imaging (MRI), along with comprehensive psychiatric assessments. The study focuses on brain regions and networks implicated in suicidality, including the anterior cingulate cortex and salience network, as well as neurochemical markers such as glutamate. It also examines electrophysiological activity and functional connectivity patterns associated with suicidal thoughts and behaviors. High-risk participants will receive an evidence-based psychotherapy called the Collaborative Assessment and Management of Suicidality (CAMS). This therapeutic approach emphasizes collaboration between patient and clinician to identify and address the underlying drivers of suicidal thoughts, with a focus on increasing hope and reducing psychological distress. Neuroimaging and clinical assessments will be repeated after completion of CAMS to evaluate treatment-related changes. The study's primary goals are to: * Identify neural and electrophysiological correlates of suicide risk. * Distinguish biological differences between individuals with suicidal ideation and those who have attempted suicide. * Determine how CAMS therapy affe
Interventions
- BEHAVIORAL CAMS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2026-06-30 |
| Est. Completion | 2031-10-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07568054
The ClinicalTrials.gov registry entry for NCT07568054 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which CAMS is the first listed.
NCT07568054 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07568054 about?
NCT07568054 is a clinical study titled "Neural Correlates of Suicidal Behavior in Youth". This study, titled "Neural Correlates of Suicidal Behavior in Youth: a Pre and Post CAMS Therapy Neuroimaging Study," aims to better understand the brain mechanisms underlying suicidal thoughts and behaviors in adolescents and young adults (ages 14-24). Suicide is a leading cause of death in this po...
What is the current status of trial NCT07568054?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2026-06-30. Estimated completion is 2031-10-01.
What interventions are being tested in trial NCT07568054?
The interventions under investigation include: CAMS (BEHAVIORAL).
Who is sponsoring clinical trial NCT07568054?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
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