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ClinicalTrials.gov 134 recruiting now full pipeline #27 of 28,707 conditions

Cardiovascular Diseases: full-pipeline trial registry

134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.

Corpus placement: #27 of 28,707 conditions by registered trial count.

304 US clinical trials · 134 currently recruiting · #27 of 28,707 conditions by registered trial count

Cardiovascular Diseases: 304 US clinical trials tracked, 134 recruiting.

Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.

Enrollment posture brief

Registry condition cardiovascular-diseases

OPEN 134 | RECR 44% | LATE 26 | EARLY 28 | RANK #27 | SPON 10

Nearest open-share peer: Suicide (44% recruiting · 93 trials)

Acute Myeloid Leukemia51.8%Chronic Pain46%Cardiovascular Diseases (thi…44%HIV35.9%COVID-1922.7%
Open-enrollment share among volume-matched conditions near Cardiovascular Diseases

Cardiovascular Diseases lists 134 open slots (44% of 304 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cardiovascular Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cardiovascular Diseases is recruiting above its size-band peers.

    134 of 304 indexed trials (44.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cardiovascular Diseases trials is spread across many organizations.

    Duke University accounts for 10 of 304 trials (3.3%). 159 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cardiovascular Diseases enrolment sits around 200 participants.

    Median target enrolment is 200 among the 301 trials that report a genuine target (sentinel values excluded). 101 of those (33.6%) plan for fewer than 100 participants.

  4. Cardiovascular Diseases research is mostly interventional.

    225 interventional and 79 observational studies make up this index (74% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 110Phase 218Phase 313Phase 413

Open and recent trials

304 total, page 1 of 7

RECRUITING 2,000,000 participants

Observational Pharmaco-Epidemiology Research & Analysis

Epividian

NCT03813862

RECRUITING 1,000,000 participants

A Study of Mayo Clinic CV Research Heart & Voice Study

Mayo Clinic

NCT07224685

RECRUITING 250,000 participants

The Oxford Risk Factors And Non-Invasive Imaging Study

University of Oxford

NCT05169333

RECRUITING 100,000 participants

DeBakey Cardiovascular Magnetic Resonance Study

Dipan Shah

NCT04281823

RECRUITING Phase 4 20,000 participants

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Duke University

NCT04262206

RECRUITING 16,000 participants

Food and Microbiome Longitudinal Investigation (FAMiLI)

NYU Langone Health

NCT03293758

RECRUITING Phase 3 11,800 participants

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Boehringer Ingelheim

NCT07064473

RECRUITING 10,000 participants

Cardiovascular and Metabolic Sciences Biorepository

The Cleveland Clinic

NCT06560424

RECRUITING 10,000 participants

Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility

Brooklyn Clinical Research

NCT06412536

RECRUITING open-ended (no fixed target)

Cardiovascular Health Improvement Project

University of Michigan

NCT02306200

RECRUITING 7,000 participants

CVD/PH and Voice Characteristics

Mayo Clinic

NCT07311044

RECRUITING 7,000 participants

Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.

Clindove Research

NCT07106879

RECRUITING 5,000 participants

Global Cardio Oncology Registry

The Cleveland Clinic

NCT05598879

RECRUITING NA 3,904 participants

Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"

NHS Greater Glasgow and Clyde

NCT05919342

RECRUITING NA 3,306 participants

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

University of British Columbia

NCT03674307

RECRUITING NA 2,100 participants

Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors

University of Colorado, Denver

NCT06324981

RECRUITING 2,000 participants

Phase I Human Analytics (HALO) Study

HALO Diagnostics

NCT05423860

RECRUITING 2,000 participants

Diabetes and Heart Disease Risk in Blacks

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00001853

RECRUITING 2,000 participants

Aging, Geriatric Syndromes and Clonal Hematopoiesis

Washington University School of Medicine

NCT02604563

RECRUITING NA 1,605 participants

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

Concept Medical

NCT06271590

RECRUITING 1,000 participants

Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

Medtronic Vascular

NCT07174622

RECRUITING 1,000 participants

Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study

Duke University

NCT06604650

RECRUITING 1,000 participants

Mayo AVC Registry and Biobank

Mayo Clinic

NCT03049254

RECRUITING 1,000 participants

The RADIANCE CED Study

ReCor Medical

NCT07231757

RECRUITING 1,000 participants

Pivotal Study for the Cardiac Performance System (CPS)

Sensydia Corporation

NCT06870591

RECRUITING 1,000 participants

Thrombosis and Inflammation in Vessels Initiative (TIVI)

National Heart, Lung, and Blood Institute (NHLBI)

NCT06552767

RECRUITING 1,000 participants

Global Paradise System US Post Approval Study

ReCor Medical

NCT06297291

RECRUITING NA 1,000 participants

Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

AliveCor

NCT06271577

RECRUITING 1,000 participants

Development of CIRC Technologies

The Cleveland Clinic

NCT05654272

RECRUITING NA 994 participants

GC-PRO Intervention

University of Minnesota

NCT06671704

RECRUITING NA 900 participants

Healthy School Recognized Campus: A Hybrid Type 2 Implementation-Effectiveness Trial

Texas A&M University

NCT07079995

RECRUITING NA 850 participants

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Abbott Medical Devices

NCT06526195

RECRUITING NA 835 participants

Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project

University of Louisville

NCT03670524

RECRUITING NA 806 participants

Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health

Tulane University

NCT06065098

RECRUITING NA 780 participants

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

BrioHealth Solutions

NCT06310031

RECRUITING NA 750 participants

Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

Ohio State University

NCT06586970

RECRUITING NA 700 participants

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Fundación EPIC

NCT07286578

RECRUITING 650 participants

Military Health and Nutrition Examination Study

Pennington Biomedical Research Center

NCT06380322

RECRUITING NA 560 participants

Enhancing Capacity in Churches to Implement PA Programs

San Diego State University

NCT05473871

RECRUITING NA 520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

University of Pennsylvania

NCT05908240

RECRUITING 500 participants

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

University of New Mexi

NCT04185844

RECRUITING NA 500 participants

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

University of South Carolina

NCT05370014

RECRUITING 500 participants

Biobank Cardiac Surgery

University of Chicago

NCT06747806

RECRUITING NA 500 participants

Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments

Texas A&M University

NCT05867433

RECRUITING NA 500 participants

Philly CEAL- DECIDE+ Adaptation

University of Pennsylvania

NCT06732102

RECRUITING 500 participants

Vascular Lab Resource (VLR) Biorepository

The Cleveland Clinic

NCT05628948

RECRUITING 500 participants

CARBON: UAB Cardiovascular Research Biobank

University of Alabama at Birmingham

NCT05067231

RECRUITING NA 492 participants

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

Concept Medical

NCT05908331

RECRUITING NA 450 participants

Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs

Pritikin ICR

NCT06424119

RECRUITING NA 450 participants

Cerebrovascular Health and Resilience in Midlife

University of Pittsburgh

NCT06029348

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 18
Phase 3 13
Phase 4 13

Named interventions

Most-linked intervention names on Cardiovascular Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
9 trials
Placebo Dietary supplement
4 trials
Aspirin Drug
3 trials
Corus CAD (ASGES) Diagnostic test
2 trials
Medication Drug
2 trials
Tendyne Mitral Valve System Device
2 trials
Social Determinants of Health Other
2 trials
Lifestyle Behavioral
2 trials

US sites by state

Facility locations filed on Cardiovascular Diseases trials. A trial with sites in several states counts in each.

California 60 trials
Massachusetts 38 trials
New York 37 trials
Pennsylvania 36 trials
Illinois 33 trials
Florida 30 trials
Minnesota 28 trials
Georgia 27 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cardiovascular Diseases page

304 registered trials, 134 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 134 Cardiovascular Diseases trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Duke University sponsors the most Cardiovascular Diseases trials on record, review their full trial history before evaluating a specific study. See Duke University's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiovascular Diseases condition card totals 304 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.