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ClinicalTrials.gov 134 recruiting now official registry

Cardiovascular Diseases clinical trials

134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.

304 US clinical trials · 134 currently recruiting

Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.

The research picture

Cardiovascular Diseases has 304 registered US clinical trials, 134 of them open to new participants right now, about 44% of the total.

134
recruiting participants now
44%
of trials open to enrollment
26
in Phase 3–4 (later-stage)
10
top sponsor: Duke University
Phase 110Phase 218Phase 313Phase 413

Active & Recent Trials

304 total, page 1 of 7

RECRUITING 2,000,000 participants

Observational Pharmaco-Epidemiology Research & Analysis

Epividian

NCT03813862

RECRUITING 1,000,000 participants

A Study of Mayo Clinic CV Research Heart & Voice Study

Mayo Clinic

NCT07224685

RECRUITING 250,000 participants

The Oxford Risk Factors And Non-Invasive Imaging Study

University of Oxford

NCT05169333

RECRUITING 100,000 participants

DeBakey Cardiovascular Magnetic Resonance Study

Dipan Shah

NCT04281823

RECRUITING Phase 4 20,000 participants

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Duke University

NCT04262206

RECRUITING 16,000 participants

Food and Microbiome Longitudinal Investigation (FAMiLI)

NYU Langone Health

NCT03293758

RECRUITING Phase 3 11,800 participants

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Boehringer Ingelheim

NCT07064473

RECRUITING 10,000 participants

Cardiovascular and Metabolic Sciences Biorepository

The Cleveland Clinic

NCT06560424

RECRUITING 10,000 participants

Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility

Brooklyn Clinical Research

NCT06412536

RECRUITING open-ended (no fixed target)

Cardiovascular Health Improvement Project

University of Michigan

NCT02306200

RECRUITING 7,000 participants

CVD/PH and Voice Characteristics

Mayo Clinic

NCT07311044

RECRUITING 7,000 participants

Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.

Clindove Research

NCT07106879

RECRUITING 5,000 participants

Global Cardio Oncology Registry

The Cleveland Clinic

NCT05598879

RECRUITING NA 3,904 participants

Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"

NHS Greater Glasgow and Clyde

NCT05919342

RECRUITING NA 3,306 participants

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

University of British Columbia

NCT03674307

RECRUITING NA 2,100 participants

Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors

University of Colorado, Denver

NCT06324981

RECRUITING 2,000 participants

Phase I Human Analytics (HALO) Study

HALO Diagnostics

NCT05423860

RECRUITING 2,000 participants

Diabetes and Heart Disease Risk in Blacks

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00001853

RECRUITING 2,000 participants

Aging, Geriatric Syndromes and Clonal Hematopoiesis

Washington University School of Medicine

NCT02604563

RECRUITING NA 1,605 participants

MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

Concept Medical

NCT06271590

RECRUITING 1,000 participants

Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

Medtronic Vascular

NCT07174622

RECRUITING 1,000 participants

Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study

Duke University

NCT06604650

RECRUITING 1,000 participants

Mayo AVC Registry and Biobank

Mayo Clinic

NCT03049254

RECRUITING 1,000 participants

The RADIANCE CED Study

ReCor Medical

NCT07231757

RECRUITING 1,000 participants

Pivotal Study for the Cardiac Performance System (CPS)

Sensydia Corporation

NCT06870591

RECRUITING 1,000 participants

Thrombosis and Inflammation in Vessels Initiative (TIVI)

National Heart, Lung, and Blood Institute (NHLBI)

NCT06552767

RECRUITING 1,000 participants

Global Paradise System US Post Approval Study

ReCor Medical

NCT06297291

RECRUITING NA 1,000 participants

Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

AliveCor

NCT06271577

RECRUITING 1,000 participants

Development of CIRC Technologies

The Cleveland Clinic

NCT05654272

RECRUITING NA 994 participants

GC-PRO Intervention

University of Minnesota

NCT06671704

RECRUITING NA 900 participants

Healthy School Recognized Campus: A Hybrid Type 2 Implementation-Effectiveness Trial

Texas A&M University

NCT07079995

RECRUITING NA 850 participants

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Abbott Medical Devices

NCT06526195

RECRUITING NA 835 participants

Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project

University of Louisville

NCT03670524

RECRUITING NA 806 participants

Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health

Tulane University

NCT06065098

RECRUITING NA 780 participants

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

BrioHealth Solutions

NCT06310031

RECRUITING NA 750 participants

Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

Ohio State University

NCT06586970

RECRUITING NA 700 participants

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Fundación EPIC

NCT07286578

RECRUITING 650 participants

Military Health and Nutrition Examination Study

Pennington Biomedical Research Center

NCT06380322

RECRUITING NA 560 participants

Enhancing Capacity in Churches to Implement PA Programs

San Diego State University

NCT05473871

RECRUITING NA 520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

University of Pennsylvania

NCT05908240

RECRUITING 500 participants

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

University of New Mexi

NCT04185844

RECRUITING NA 500 participants

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

University of South Carolina

NCT05370014

RECRUITING 500 participants

Biobank Cardiac Surgery

University of Chicago

NCT06747806

RECRUITING NA 500 participants

Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments

Texas A&M University

NCT05867433

RECRUITING NA 500 participants

Philly CEAL- DECIDE+ Adaptation

University of Pennsylvania

NCT06732102

RECRUITING 500 participants

Vascular Lab Resource (VLR) Biorepository

The Cleveland Clinic

NCT05628948

RECRUITING 500 participants

CARBON: UAB Cardiovascular Research Biobank

University of Alabama at Birmingham

NCT05067231

RECRUITING NA 492 participants

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

Concept Medical

NCT05908331

RECRUITING NA 450 participants

Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs

Pritikin ICR

NCT06424119

RECRUITING NA 450 participants

Cerebrovascular Health and Resilience in Midlife

University of Pittsburgh

NCT06029348

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Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 18
Phase 3 13
Phase 4 13

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cardiovascular Diseases Trial Landscape

304 indexed Cardiovascular Diseases studies · 134 recruiting (44%).

Phase mix: 26 late (III/IV) vs 28 early (I/II).

Top sponsor: Duke University (10 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cardiovascular Diseases?

PlainTrial tracks 304 US clinical trials for Cardiovascular Diseases, of which 134 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cardiovascular Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.