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NCT03288025 · ClinicalTrials.gov registry record · NA
Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE)
A NA study of Insulin Resistance and Pulmonary Arterial Hypertension, sponsored by The Cleveland Clinic.
- Active
- Registry status
- NA
- Development phase
- 34
- Enrollment target
- 1
- Study location
NCT03288025: Active NA study of Insulin Resistance and Pulmonary Arterial Hypertension, sponsored by The Cleveland Clinic.
NCT03288025 is a NA study of Insulin Resistance and Pulmonary Arterial Hypertension that is active but no longer recruiting, run by The Cleveland Clinic. The registered enrollment target is 34 participants, below the 245-participant average among 120 other Insulin Resistance trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03288025, a NA study of Insulin Resistance and Pulmonary Arterial Hypertension, is active but no longer recruiting, sponsored by The Cleveland Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 34 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate the extent to which diet and exercise may improve PAH through the modulation of insulin sensitivity. The central hypothesis is that dysregulated glucose metabolism elicits a response in PAH patients that can be modified by exercise and diet, thereby leading to improvements in pulmonary vascular disease.
Primary Outcome
Assessed by the frequently-sampled intravenous glucose tolerance test. Units of assessment in min/uU\*mL
Conditions Studied
Interventions
- BEHAVIORAL Nutrition and Exercise
Study Locations (1)
Ohio
- Cleveland Clinic Foundation - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2017-09-27 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What the registry record for NCT03288025 still lists
NCT03288025 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 245-participant average among 120 other Insulin Resistance trials with a reported enrollment target (86% lower).
The record links to 2 conditions, with Insulin Resistance appearing as the primary indexed condition, and to 1 intervention - of which Nutrition and Exercise is the first listed.
NCT03288025 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT03288025 about?
NCT03288025 is a clinical study titled "Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE)". The purpose of this study is to investigate the extent to which diet and exercise may improve PAH through the modulation of insulin sensitivity. The central hypothesis is that dysregulated glucose metabolism elicits a response in PAH patients that can be modified by exercise and diet, thereby leadin...
What is the current status of trial NCT03288025?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 34 participants. The study started on 2017-09-27. Estimated completion is 2026-06-30.
What conditions does trial NCT03288025 study?
This clinical trial studies the following conditions: Insulin Resistance, Pulmonary Arterial Hypertension.
What interventions are being tested in trial NCT03288025?
The interventions under investigation include: Nutrition and Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT03288025?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03288025 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03288025's enrollment target sits among peer trials
34 82nd of 120 higher than 39 of 120 other Insulin Resistance trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Insulin Resistance trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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