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ClinicalTrials.gov 6 recruiting now official registry

Uveitis clinical trials

Every US clinical trial registered for Uveitis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

21 US clinical trials · 6 currently recruiting

The research picture

Uveitis has 21 registered US clinical trials, 6 of them open to new participants right now — about 29% of the total.

6
recruiting participants now
29%
of trials open to enrollment
6
in Phase 3–4 (later-stage)
6
top sponsor: National Eye Institute (NEI)

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 1,500 participants

Genetics of Uveitis

The Cleveland Clinic

NCT02357238

RECRUITING 1,500 participants

Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography

The Cleveland Clinic

NCT01746537

RECRUITING 290 participants

RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age

Meyer Children's Hospital IRCCS

NCT06273748

RECRUITING NA 100 participants

Ocular Pathogen and Transcriptome Investigation Using Comprehensive Sequencing

University of California, San Francis

NCT05286203

RECRUITING Phase 3 30 participants

The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment

Texas Retina Associates

NCT05486468

RECRUITING Phase 1 12 participants

Safety, Tolerability, and Distribution of Laquinimod Eye Drops : The LION Study

Quan Dong Nguyen

NCT06161415

ACTIVE NOT RECRUITING Phase 3 371 participants

A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis

Priovant Therapeutics

NCT06431373

ACTIVE NOT RECRUITING 50 participants

Imaging Quantification of Inflammation (IQI)

The Cleveland Clinic

NCT04704609

COMPLETED 6,300 participants

Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study

National Eye Institute (NEI)

NCT00116090

COMPLETED 609 participants

Genetics and Markers of Degenerative and Inflammatory Eye Diseases

National Eye Institute (NEI)

NCT00647439

COMPLETED Phase 3 194 participants

Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial

JHSPH Center for Clinical Trials

NCT02623426

COMPLETED Phase 3 192 participants

PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial

JHSPH Center for Clinical Trials

NCT02374060

COMPLETED Phase 3 160 participants

Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis

Clearside Biomedical

NCT02595398

COMPLETED 131 participants

Intestinal Bacteria and Ocular Inflammatory Disease

National Eye Institute (NEI)

NCT01859299

COMPLETED 100 participants

Flare Photometry in Uveitis Patients

ChromoLogic

NCT01897935

COMPLETED 100 participants

Immune Indicators of Uveitis

National Eye Institute (NEI)

NCT00089739

COMPLETED 33 participants

MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301

Clearside Biomedical

NCT02952001

COMPLETED Phase 1 31 participants

Optiquel® as Corticosteroid-sparing Therapy for Chronic Noninfectious Uveitis

National Eye Institute (NEI)

NCT01195948

COMPLETED Phase 2 22 participants

Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis

Clearside Biomedical

NCT02255032

COMPLETED Phase 2 8 participants

Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis (STAR Study)

National Eye Institute (NEI)

NCT02911116

COMPLETED Phase 3

Study of Difluprednate in the Treatment of Uveitis

Sirion Therapeutics

NCT00501579

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 3 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Uveitis Trial Landscape

ClinicalTrials.gov lists 21 US studies indexed under Uveitis, and 6 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Uveitis shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Uveitis is led by National Eye Institute (NEI) with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 21 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Uveitis?

PlainTrial tracks 21 US clinical trials for Uveitis, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Uveitis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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