The Cleveland Clinic
Open enrollment across a mixed-phase pipeline
According to ClinicalTrials.gov-derived indexes, The Cleveland Clinic sits in the top decile of US sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count).
The Cleveland Clinic: 688 sponsored US clinical trials, 99 recruiting.
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Top-decile sponsor footprint
The Cleveland Clinic ranks in the top decile of sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
437 of 539 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
688 total, page 2 of 14
Evaluation of Outcomes of the Triathlon Hinge Knee (THK) System
NCT06379321
Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes
NCT06382636
Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor
NCT06293638
Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes
NCT06298721
Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study
NCT06193512
Rebuilding Inter-limb Transfer in Cervical SCI
NCT06440538
Precise and Objective Identification of Bertolotti Syndrome Using Novel Kinematic Biomarkers
NCT06225583
Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate
NCT06179654
Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue
NCT06789809
Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
NCT05868668
Phenotypic Classification of FMR With CMR
NCT05965258
Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis
NCT05993546
Home Versus Office Removal of Percutaneous Nerve Evaluation (PNE) Lead
NCT05799313
Molecular Mechanism of Exercise in Cirrhosis
NCT05982769
Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients
NCT05725928
Intraoperative Electrical Stimulation to Improve Nerve Grafting Outcome
NCT06335719
Intracardiac Echocardiography Guided Watchman Device Implant
NCT06007872
CV Imaging of Metabolic Interventions
NCT05650307
Development of CIRC Technologies
NCT05654272
HA35 Moderate Alcoholic Hepatitis (AH) Study
NCT05018481
Global Cardio Oncology Registry
NCT05598879
HA35 Acute Alcohol Study
NCT05025865
HMB Enriched Amino Acids to Reverse Muscle Loss in Cirrhosis
NCT05166499
Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)
NCT04869813
Study of HMB-enriched Amino Acid Supplementation in Patients With Alcoholic Liver Disease and COVID-19
NCT04858412
Structural Modification In Supraglottic Airway Device
NCT04498598
MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES)
NCT04578392
Dextenza in the Post-op Management of Vitreoretinal Surgeries
NCT04371445
Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)
NCT05628974
Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy
NCT04310241
Vascular Lab Resource (VLR) Biorepository
NCT05628948
Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study
NCT04191681
Peripheral Blood Mononuclear Cells Response In Healthy Controls, Heavy Drinkers, and Patients With Alcoholic Hepatitis
NCT04088370
Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy
NCT04096014
A Cardiac Disease Quality of Life Study
NCT04080492
Comparative Imaging Assessment of Valvular Heart Disease
NCT04126018
rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke
NCT03870672
Novel Tracer Methods to Evaluate Muscle Protein Metabolism in Cirrhosis
NCT03225677
Comparison of ALD, NASH, and Healthy Control Patients
NCT03224949
Can Prophylactic Foraminotomy Prevent C5 Palsy
NCT03023696
Corneal Elastography and Patient Specific Modeling
NCT03030755
Ethanol Induces Skeletal Muscle Autophagy
NCT03209791
Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)
NCT02016430
DISCOVER Study: Microscope-integrated Intraoperative OCT Study
NCT02423213
Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis
NCT03208868
Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography
NCT01746537
Genetics of Uveitis
NCT02357238
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
NCT00921986
Mechanisms of Malnutrition in Cirrhosis With Portosystemic Shunting
NCT03121404
Neuromodulation With Percutaneous Electrical Nerve Field Stimulation
NCT07492108
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What is open in the The Cleveland Clinic pipeline
99 recruiting of 688 indexed (14% open); 437 completed (64%).
Phase mix: 81 late (III/IV) vs 76 early (I/II) (balanced across stages).
Top condition: Atrial Fibrillation (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
The Cleveland Clinic: open-pipeline peers nationwide
Peers matched on 688 registered trials and 14% open enrollment, not the therapeutic-area sidebar.
The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 688 trials (± recruiting share)
- Vanderbilt University Medical Center · 677 trials · 19% recruiting
- Weill Medical College of Cornell University · 701 trials · 18% recruiting
- Icahn School of Medicine at Mount Sinai · 708 trials · 23% recruiting
- Sanofi · 713 trials · 10% recruiting
Sponsors near 14% open enrollment (± trial volume)
- Dana-Farber Cancer Institute · 14% recruiting · 781 trials
- ModernaTX · 14% recruiting · 90 trials
- Masonic Cancer Center, University of Minnesota · 14% recruiting · 249 trials
- Academic and Community Cancer Research United · 14% recruiting · 42 trials
Related
What to do with this The Cleveland Clinic page
688 registered trials is a research-attention snapshot, not an endorsement of The Cleveland Clinic or any single study.
- 99 of The Cleveland Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Atrial Fibrillation is the condition The Cleveland Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. The Cleveland Clinic pipeline card: 688 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.