The Cleveland Clinic
Open enrollment across a mixed-phase pipeline
According to ClinicalTrials.gov-derived indexes, The Cleveland Clinic sits in the top decile of US sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count).
The Cleveland Clinic: 688 sponsored US clinical trials, 99 recruiting.
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Top-decile sponsor footprint
The Cleveland Clinic ranks in the top decile of sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
437 of 539 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
688 total, page 1 of 14
Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD
NCT07680283
Health-Related Quality of Life and Metabolic Outcomes in PCOS
NCT07571915
Wearable Technology in Heart Failure Patients
NCT07650669
Dietary Tracking in Heart Failure
NCT07649148
Centered Surgery - Preoperative Counseling and Patient Satisfaction
NCT07471464
Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study
NCT07363343
Feasibility and Ergonomic Impact of A Virtual Reality Headset in Endoscopic Procedures
NCT07493863
Virtual Patient Groups for Sarcoidosis Associated Fatigue
NCT07073963
Antiseptic-Coated Sutures and Pancreatic Fistula Risk After Pancreatoduodenectomy
NCT07318493
Laser Ablation a Salvage Treatment for Obstructive Benign Prostatic Hyperplasia
NCT07016620
Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion
NCT07315204
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
NCT07058155
Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training
NCT07681973
Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease
NCT07110376
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
NCT07222072
Preoperative BOTOX® Injection for Large Ventral Hernia Repair
NCT07220382
At-Home Bowel Stimulation
NCT07574437
Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD
NCT07059637
Central Vein Sign in Multiple Sclerosis Extension Study
NCT07424027
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
NCT07087587
Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Surgery
NCT06946368
Zimmer ActivBraid Rotator Cuff Repair (RCR) Study
NCT06971497
The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality
NCT07127354
BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease
NCT07138560
Non-Narcotic Pain Control After ACL Reconstruction
NCT06973785
Gluten Free Diet in Hashimoto's Hypothyroidism
NCT07060118
Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF
NCT07122947
Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis
NCT06857240
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution
NCT06795035
Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor
NCT07049003
Randomized Trial of Cold EMR Compared to Hybrid Cold EMR.
NCT06937671
Early Versus Late Adjunctive Vasopressin in Septic Shock
NCT06709573
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
NCT06802081
CLOSM Trial: Groin Closure Using Layered Option for Suture Material
NCT06990425
Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF
NCT06849752
Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease
NCT06694558
Impact of Medjool Date Consumption on Labor and Delivery Outcomes
NCT07058792
Physician Modified Endovascular Grafts for the Treatment of Juxtarenal Aortic Aneurysms
NCT06657794
Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables
NCT06818760
Imaging Assessments of ARPKD Kidney Disease Progression
NCT07201025
Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease
NCT06780241
Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy
NCT06721520
Detecting Mild Autonomous Cortisol Secretion in Patients With Adrenal Incidentaloma
NCT06344143
Quantra Point-of-Care Hemostasis Monitoring
NCT06328647
I-Score: Intensive Stroke Cycling for Optimal Recovery and Economic Value
NCT06585943
Cardiovascular and Metabolic Sciences Biorepository
NCT06560424
NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow
NCT06373978
EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery
NCT06409156
Sugammadex Vs Neostigmine in Reversing Neuromuscular Blocks in Outpatient ERCP. A Randomized, Double-Blinded Trial
NCT06136585
Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy
NCT06407024
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What is open in the The Cleveland Clinic pipeline
99 recruiting of 688 indexed (14% open); 437 completed (64%).
Phase mix: 81 late (III/IV) vs 76 early (I/II) (balanced across stages).
Top condition: Atrial Fibrillation (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
The Cleveland Clinic: open-pipeline peers nationwide
Peers matched on 688 registered trials and 14% open enrollment, not the therapeutic-area sidebar.
The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 688 trials (± recruiting share)
- Vanderbilt University Medical Center · 677 trials · 19% recruiting
- Weill Medical College of Cornell University · 701 trials · 18% recruiting
- Icahn School of Medicine at Mount Sinai · 708 trials · 23% recruiting
- Sanofi · 713 trials · 10% recruiting
Sponsors near 14% open enrollment (± trial volume)
- Dana-Farber Cancer Institute · 14% recruiting · 781 trials
- ModernaTX · 14% recruiting · 90 trials
- Masonic Cancer Center, University of Minnesota · 14% recruiting · 249 trials
- Academic and Community Cancer Research United · 14% recruiting · 42 trials
Related
What to do with this The Cleveland Clinic page
688 registered trials is a research-attention snapshot, not an endorsement of The Cleveland Clinic or any single study.
- 99 of The Cleveland Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Atrial Fibrillation is the condition The Cleveland Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
The Cleveland Clinic pipeline card: 688 registered trials from official public datasets.Report a data error.