The Cleveland Clinic
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Trial Pipeline
688 total, page 1 of 14
Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD
NCT07680283
Health-Related Quality of Life and Metabolic Outcomes in PCOS
NCT07571915
Wearable Technology in Heart Failure Patients
NCT07650669
Dietary Tracking in Heart Failure
NCT07649148
Centered Surgery - Preoperative Counseling and Patient Satisfaction
NCT07471464
Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study
NCT07363343
Feasibility and Ergonomic Impact of A Virtual Reality Headset in Endoscopic Procedures
NCT07493863
Virtual Patient Groups for Sarcoidosis Associated Fatigue
NCT07073963
Antiseptic-Coated Sutures and Pancreatic Fistula Risk After Pancreatoduodenectomy
NCT07318493
Laser Ablation a Salvage Treatment for Obstructive Benign Prostatic Hyperplasia
NCT07016620
Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion
NCT07315204
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
NCT07058155
Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training
NCT07681973
Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease
NCT07110376
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
NCT07222072
Preoperative BOTOX® Injection for Large Ventral Hernia Repair
NCT07220382
At-Home Bowel Stimulation
NCT07574437
Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD
NCT07059637
Central Vein Sign in Multiple Sclerosis Extension Study
NCT07424027
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
NCT07087587
Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Surgery
NCT06946368
Zimmer ActivBraid Rotator Cuff Repair (RCR) Study
NCT06971497
The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality
NCT07127354
BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease
NCT07138560
Non-Narcotic Pain Control After ACL Reconstruction
NCT06973785
Gluten Free Diet in Hashimoto's Hypothyroidism
NCT07060118
Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF
NCT07122947
Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis
NCT06857240
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution
NCT06795035
Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor
NCT07049003
Randomized Trial of Cold EMR Compared to Hybrid Cold EMR.
NCT06937671
Early Versus Late Adjunctive Vasopressin in Septic Shock
NCT06709573
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
NCT06802081
CLOSM Trial: Groin Closure Using Layered Option for Suture Material
NCT06990425
Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF
NCT06849752
Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease
NCT06694558
Impact of Medjool Date Consumption on Labor and Delivery Outcomes
NCT07058792
Physician Modified Endovascular Grafts for the Treatment of Juxtarenal Aortic Aneurysms
NCT06657794
Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables
NCT06818760
Imaging Assessments of ARPKD Kidney Disease Progression
NCT07201025
Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease
NCT06780241
Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy
NCT06721520
Detecting Mild Autonomous Cortisol Secretion in Patients With Adrenal Incidentaloma
NCT06344143
Quantra Point-of-Care Hemostasis Monitoring
NCT06328647
I-Score: Intensive Stroke Cycling for Optimal Recovery and Economic Value
NCT06585943
Cardiovascular and Metabolic Sciences Biorepository
NCT06560424
NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow
NCT06373978
EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery
NCT06409156
Sugammadex Vs Neostigmine in Reversing Neuromuscular Blocks in Outpatient ERCP. A Randomized, Double-Blinded Trial
NCT06136585
Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy
NCT06407024
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What the Pipeline for The Cleveland Clinic Shows
According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.
The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.