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NCT01759186 · ClinicalTrials.gov registry record

Airway Redox and Gender Determinants in Severe Asthma

A clinical trial of Asthma, sponsored by The Cleveland Clinic.

Active
Registry status
300
Enrollment target
4
Study locations

NCT01759186 is a study of Asthma that is active but no longer recruiting, run by The Cleveland Clinic. The registered enrollment target is 300 participants, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (81% lower). The trial reports 4 study locations across 2 states.

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The verdict

NCT01759186, a study of Asthma, is active but no longer recruiting, sponsored by The Cleveland Clinic.

ACTIVE NOT RECRUITING
Registry status
300 participants
Enrollment target
4
Study locations

Study Summary

The investigators will study the biologic and chemical differences that cause the greater incidence, and severity of asthma in women as compared to men. Severe asthma affects boys more than girls, while severe asthma in adults is predominantly a disease of women. The investigators aim to identify the processes that occur in the body that are behind the onset of severe asthma in young women during the teenage years, and the resolution of severe asthma in boys. To further evaluate gender influences on asthma, asthmatic women at different stages of their menstrual cycle (period) will be also studied. The investigators aim to use biomarkers to develop testing procedures that will identify different types or characteristics of asthma in men and women; and to follow patients over time to uncover relevant clinical outcomes of biomarkers. The investigators anticipate that they will 1) develop clinically relevant tests to identify unique types or characteristics of asthma and severe asthma; 2) determine outcomes over time of biochemically-defined types of asthma; and 3) identify the reasons for why adult women are affected more than men with severe asthma.

Conditions Studied

Asthma

Study Locations (4)

Ohio

  • Rainbow Babies and Children's Hospital - Cleveland
  • Cleveland Clinic - Cleveland

Virginia

  • University of Virginia - Charlottesville
  • Virginia Commonwealth University - Richmond

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2012-12
Est. Completion 2027-08

Sponsor

The Cleveland Clinic

688 total trials

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What the Registry Record Tells You About NCT01759186

The ClinicalTrials.gov registry entry for NCT01759186 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (81% lower). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Asthma appearing as the primary indexed condition, and to 0 interventions.

NCT01759186 reports 4 study locations spanning 2 distinct geographic areas - top geographies include Ohio, Virginia.

Frequently Asked Questions

What is clinical trial NCT01759186 about?

NCT01759186 is a clinical study titled "Airway Redox and Gender Determinants in Severe Asthma". The investigators will study the biologic and chemical differences that cause the greater incidence, and severity of asthma in women as compared to men. Severe asthma affects boys more than girls, while severe asthma in adults is predominantly a disease of women. The investigators aim to identify th...

What is the current status of trial NCT01759186?

This trial is currently active not recruiting. The enrollment target is 300 participants. The study started on 2012-12. Estimated completion is 2027-08.

What conditions does trial NCT01759186 study?

This clinical trial studies the following conditions: Asthma.

Who is sponsoring clinical trial NCT01759186?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01759186 being conducted?

This trial has 4 study locations across Ohio, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.