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NCT04827368 · ClinicalTrials.gov registry record
Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease
A clinical trial of Ulcerative Colitis and Crohn Disease, sponsored by The Cleveland Clinic.
- Active
- Registry status
- 292
- Enrollment target
- 1
- Study location
NCT04827368: Active study of Ulcerative Colitis and Crohn Disease, sponsored by The Cleveland Clinic.
NCT04827368 is a study of Ulcerative Colitis and Crohn Disease that is active but no longer recruiting, run by The Cleveland Clinic. The registered enrollment target is 292 participants, below the 2,055-participant average among 122 other Ulcerative Colitis trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04827368, a study of Ulcerative Colitis and Crohn Disease, is active but no longer recruiting, sponsored by The Cleveland Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- 292 participants
- Enrollment target
- 1
- Study location
Study Summary
Inflammatory Bowel Disease (IBD) are chronic diseases of the gut comprising Crohn's Disease (CD) and Ulcerative Colitis (UC). The symptoms of IBD consist of diarrhea, abdominal discomfort, weight loss, fatigue and rectal bleeding. However, symptoms and treatment vary between patients. Early management of IBD can lead to better response rates and decrease the risk of irreversible bowel damage and future disease complications such as surgeries. Current clinical tools for diagnosis and or assessing progression of IBD are either invasive (colonoscopy), have low patient acceptance (fecal calprotectin) or low accuracy (C-reactive protein). The purpose of this study is to collect clinical data and samples (including blood, breath and stool) donated by patients with IBD and patients with no IBD (controls) to facilitate research that may result in the development of new non-invasive methods of diagnosing IBD and understand the progression of the disease over time in order to better manage IBD patients.
Primary Outcome
Correlation of breath VOCs with changes in Fecal Calprotectin.
Conditions Studied
Interventions
- OTHER Breath Test
Study Locations (1)
Ohio
- Cleveland Clinic - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 292 participants |
| Start Date | 2021-03-22 |
| Est. Completion | 2026-06-30 |
What the registry record for NCT04827368 still lists
NCT04827368 is an observational study that tracks outcomes without assigning an intervention. The registered 292 participants enrollment target is mid-sized for trials with a published cap, below the 2,055-participant average among 122 other Ulcerative Colitis trials with a reported enrollment target (86% lower).
The record links to 3 conditions, with Ulcerative Colitis appearing as the primary indexed condition, and to 1 intervention - of which Breath Test is the first listed.
NCT04827368 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT04827368 about?
NCT04827368 is a clinical study titled "Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease". Inflammatory Bowel Disease (IBD) are chronic diseases of the gut comprising Crohn's Disease (CD) and Ulcerative Colitis (UC). The symptoms of IBD consist of diarrhea, abdominal discomfort, weight loss, fatigue and rectal bleeding. However, symptoms and treatment vary between patients. Early manageme...
What is the current status of trial NCT04827368?
This trial is currently active not recruiting. The enrollment target is 292 participants. The study started on 2021-03-22. Estimated completion is 2026-06-30.
What conditions does trial NCT04827368 study?
This clinical trial studies the following conditions: Ulcerative Colitis, Crohn Disease, IBD.
What interventions are being tested in trial NCT04827368?
The interventions under investigation include: Breath Test (OTHER).
Who is sponsoring clinical trial NCT04827368?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04827368 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04827368's enrollment target sits among peer trials
292 34th of 122 higher than 89 of 122 other Ulcerative Colitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ulcerative Colitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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