Icahn School of Medicine at Mount Sinai

946 total trials 808 currently recruiting 111 completed

Trial Pipeline

RECRUITING Phase 4

Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant

NCT07059494

RECRUITING NA

Paired Non-invasive VNS in Adolescent Cerebral Palsy Rehabilitation

NCT07394608

RECRUITING Phase 2

Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer

NCT07027124

RECRUITING NA

Impact of Morning Light Therapy in IBD

NCT07207200

RECRUITING Phase 1

Alnuctamab for Refractory SLE (LATTE Study)

NCT07219563

RECRUITING NA

Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder

NCT07318480

RECRUITING Phase 2

Diagnostic Utility of rhPSMA-7.3 (18F) PET/CT in Men With Prostate Cancer on Active Surveillance

NCT07285057

RECRUITING NA

Virtual Reality (VR) Self-Hypnosis Software

NCT06398847

RECRUITING Phase 2

Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome

NCT07242638

RECRUITING NA

The Use of Rhythmic Light Therapy in Mild Cognitive Impairment

NCT07318038

RECRUITING NA

Evaluating a Prototype CT Scan for ICH Evacuation

NCT07455201

RECRUITING Phase 1

Study of Cannabidiol and Neuroimaging on Stress

NCT07278505

RECRUITING Phase 4

CaOx Stone Prevention

NCT07225764

RECRUITING

Liver Transplant CGM

NCT07216508

RECRUITING NA

Validating CGM for GDM

NCT06858787

RECRUITING NA

Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation

NCT06938412

RECRUITING NA

Multifaceted Intervention to Restore Resilience and Overcome Risk

NCT06988787

RECRUITING NA

Assessment of Music Experiences in Navigating Depression Part 2

NCT07218055

RECRUITING NA

Transcranial Magnetic Stimulation in Misophonia

NCT06960083

RECRUITING NA

ADAPT: Approach to Dance for Autism

NCT07216768

RECRUITING Phase 1

A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation

NCT07058974

RECRUITING NA

Paired Vagus Nerve Stimulation in Mobilization of Patients With Prolonged Disorders of Consciousness

NCT06930716

RECRUITING NA

Interventions for Promoting Kidney Transplant Empowerment

NCT06655857

RECRUITING

Pregnancy and Postpartum CGM in GDM

NCT07174245

RECRUITING NA

Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

NCT07142499

RECRUITING NA

Precision Analytic Research Methods in OCD

NCT07011901

RECRUITING NA

Virtual Reality for Pain Control in US-Guided Obstetric Needle Procedures

NCT07094451

RECRUITING Phase 3

Adjunctive Cannabidiol for Recovery From Opioid Study

NCT06940674

RECRUITING Phase 4

Acute Migraine Treatment in the ED With Gepants

NCT06985342

RECRUITING Early Phase 1

Study of the Feasibility and Efficacy of PrednisonE for Non-specifiC pleuriTis

NCT07039019

RECRUITING NA

Use of Circadian Reset Technology to Alter REM Sleep and Appetitive Control in Patients With Binge Eating Disorder

NCT06858774

RECRUITING NA

Feasibility of Timesaving When Using Histolog Confocal Laser Endomicroscopy for Margin Assessment in Prostatectomy Specimen

NCT07141121

RECRUITING NA

A Study of the MIND Diet for Persons With Multiple Sclerosis

NCT06992115

RECRUITING NA

Healing Track Clinical Trial

NCT06641102

RECRUITING NA

SeizEAR Safety Study

NCT07088835

RECRUITING Phase 3

Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19

NCT06960928

RECRUITING NA

Improving Medication Management in World Trade Center Responders

NCT07022990

RECRUITING Phase 1

Cannabidiol in Sickle Cell Disease

NCT06930703

RECRUITING Phase 2

Cannabinoids for the Reduction of Inflammation and Sickle Cell Related Pain

NCT05519111

RECRUITING

Quantitative Xylazine Measurement in ED

NCT06949605

RECRUITING NA

Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions

NCT06892691

RECRUITING

NIOSH R21 WTC Asthma

NCT07222501

RECRUITING Phase 1

Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy

NCT06653400

RECRUITING Phase 2

Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder

NCT06592833

RECRUITING NA

Resilient Together for Dementia (RT-D)

NCT06619327

RECRUITING NA

Evaluation of the Abbott i-STAT TBI Biomarker Test

NCT06766435

RECRUITING NA

Impact of a Structured Wellness Behavioral Intervention on Quality of Life in NMOSD

NCT06780709

RECRUITING Phase 2

Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression

NCT06559826

RECRUITING Phase 1

Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds

NCT06941467

RECRUITING NA

Surveillance Versus Bronchoscopy After Airway Stenting

NCT06935695

RECRUITING NA

Cocaine Cue-reactivity Incubation Study

NCT07091877

RECRUITING NA

Building Community Resilience Program

NCT06771167

RECRUITING NA

Cognitive Reappraisal Training for Borderline Personality (BPD)

NCT06772831

RECRUITING NA

Behavioral Therapy for Crohn's Disease

NCT06512597

RECRUITING NA

tVNS in Long COVID-19

NCT06585254

RECRUITING

Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)

NCT06575270

RECRUITING

SCM Muscle as a Marker for Frailty in Patients Undergoing ENT Surgery

NCT06704256

RECRUITING Phase 1

Sacituzumab Govitecan in Combination With Cisplatin in Platinum Sensitive Recurrent Ovarian and Endometrial Cancer

NCT06040970

RECRUITING Phase 1

Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

NCT06511050

RECRUITING

Vagal Nerve Stimulation in Enhanced Stroke Recovery: The VALOR Registry

NCT05694663

RECRUITING NA

High Fructose Diet, the Gut Microbiome, and Metabolic Health

NCT06329544

RECRUITING NA

Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain

NCT06655844

RECRUITING Phase 2

MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial

NCT06541249

RECRUITING Phase 2

Antiviral Clinical Trial for Long Covid-19

NCT06511063

RECRUITING NA

Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management

NCT06634810

RECRUITING NA

Asthma Symptom Perception Study

NCT06612294

RECRUITING Phase 4

Intrathecal Dexmedetomidine vs Epinephrine

NCT06418308

RECRUITING Phase 3

The Prevent Coronary Artery Disease Trial

NCT06494501

RECRUITING

Methamphetamine Cue-reactivity

NCT07086014

RECRUITING Phase 2

Ritlecitinib in Patients With Keloids or Those Undergoing Keloidectomy

NCT06373458

RECRUITING NA

Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

NCT06689176

RECRUITING NA

Rectus Sheath Block in Cardiac Surgery

NCT05833048

RECRUITING

Precision Medicine Study

NCT06338150

RECRUITING Phase 2

Dupilumab in the Treatment of Pediatric Alopecia Areata

NCT05866562

RECRUITING NA

Neurosteer Bedside Monitoring System

NCT06718764

RECRUITING Phase 3

Different Medications to Induce Labor

NCT06259097

RECRUITING

USCOM in Newly Diagnosed FGR Cases

NCT06343051

RECRUITING Phase 4

Bimekizumab in Plaque Psoriasis

NCT06336343

RECRUITING NA

Neurofeedback During Eating for Bulimia Nervosa

NCT05614024

RECRUITING

Investigation of a 3 oz Water Protocol on Patients With Tracheostomies

NCT06120790

RECRUITING NA

Enhancing Access to Supportive Services for Women of Color With Metastatic Breast Cancer

NCT06405828

RECRUITING Phase 4

Psychopharmacological Treatment of Emotional Distress

NCT06133114

RECRUITING NA

A Study of Meaning-Centered Psychotherapy for Caregivers to People With Cancer

NCT06307535

RECRUITING Phase 1

Neoadjuvant Dupilumab and Cemiplimab in Patients With Early-stage Resectable NSCLC

NCT06088771

RECRUITING Phase 4

Neural Circuit Effects of Ketamine in Depression

NCT06213324

RECRUITING

Social Isolation and Aging in Schizophrenia

NCT07419321

RECRUITING Phase 1

MTC Versus FMT in for RCDI

NCT05911997

RECRUITING

Behavioral and Cognitive Predictors of Persistent Pain and Opioid Misuse in Chronic Pain

NCT06288282

RECRUITING NA

Changes in Inhibition and Valuation After Eating

NCT05995496

RECRUITING NA

Persuasive Health Communication Intervention for HIV/HCV

NCT05968573

RECRUITING Phase 3

SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)

NCT06945315

RECRUITING

Maternal And Infant Antipsychotic Study

NCT06049953

RECRUITING NA

CTSN Embolic Protection Trial

NCT06027788

RECRUITING NA

Phase 2 - Rhythmic Light Therapy for Alzheimer's Disease Patients

NCT05016219

RECRUITING

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

NCT06001450

RECRUITING Phase 2

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

NCT05835466

RECRUITING NA

Telehealth Cognitive Behavioral Therapy for Youth at Risk for Psychosis

NCT05968560

RECRUITING NA

Community-based Implementation of Online EmReg

NCT05933629

RECRUITING NA

Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression

NCT05933148

RECRUITING NA

The Role of the Gastrointestinal-associated Lymphoid Tissue in the Cure of HIV Infection

NCT05652088

Phase Distribution

PhaseTrial count
Phase 1 173
Phase 2 54
Phase 3 64
Phase 4 72

What the Pipeline for Icahn School of Medicine at Mount Sinai Shows

According to the ClinicalTrials.gov registry, Icahn School of Medicine at Mount Sinai is linked to 946 US clinical trials across every stage of research activity. Of those, 808 studies are currently recruiting — about 85% of the sponsor's indexed portfolio — and 111 are already marked complete, representing roughly 12% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Icahn School of Medicine at Mount Sinai reports 136 late-stage studies (Phase 3 and Phase 4 combined) and 227 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Icahn School of Medicine at Mount Sinai is Prostate Cancer with 7 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial