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NCT04978636 · ClinicalTrials.gov registry record · NA
Low Tidal Volume Ventilation With Hyperoxia Avoidance During Cardiopulmonary Bypass (The FOCUS Trial)
A NA study of Cardiac Surgery, sponsored by The Cleveland Clinic.
- Active
- Registry status
- NA
- Development phase
- 5,502
- Enrollment target
- 1
- Study location
NCT04978636 is a NA study of Cardiac Surgery that is active but no longer recruiting, run by The Cleveland Clinic. The registered enrollment target is 5,502 participants, above the 456-participant average among 19 other Cardiac Surgery trials with a reported enrollment target (1107% higher). The trial reports 1 study location across 1 state.
The verdict
NCT04978636, a NA study of Cardiac Surgery, is active but no longer recruiting, sponsored by The Cleveland Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 5,502 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a multi-institutional study (CCF, UPMC, OSU) evaluating different ventilation strategies during cardiopulmonary bypass on mortality and postoperative pulmonary complications, with sub-study investigating 8-iso-prostaglandin F2a and sRAGE levels.
Conditions Studied
Interventions
- OTHER Continuous low-tidal volume ventilation with using FiO2 of 0.21
- OTHER Continuous low tidal volume ventilation with using FiO2 of 1.0
- OTHER Apnea During CPB
Study Locations (1)
Ohio
- Cleveland Clinic Foundation - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5,502 participants |
| Start Date | 2021-09-20 |
| Est. Completion | 2027-03-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04978636
The ClinicalTrials.gov registry entry for NCT04978636 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 5,502 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 456-participant average among 19 other Cardiac Surgery trials with a reported enrollment target (1107% higher). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cardiac Surgery appearing as the primary indexed condition, and to 3 interventions - of which Continuous low-tidal volume ventilation with using FiO2 of 0.21 is the first listed.
NCT04978636 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT04978636 about?
NCT04978636 is a clinical study titled "Low Tidal Volume Ventilation With Hyperoxia Avoidance During Cardiopulmonary Bypass (The FOCUS Trial)". This is a multi-institutional study (CCF, UPMC, OSU) evaluating different ventilation strategies during cardiopulmonary bypass on mortality and postoperative pulmonary complications, with sub-study investigating 8-iso-prostaglandin F2a and sRAGE levels.
What is the current status of trial NCT04978636?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 5,502 participants. The study started on 2021-09-20. Estimated completion is 2027-03-30.
What conditions does trial NCT04978636 study?
This clinical trial studies the following conditions: Cardiac Surgery.
What interventions are being tested in trial NCT04978636?
The interventions under investigation include: Continuous low-tidal volume ventilation with using FiO2 of 0.21 (OTHER), Continuous low tidal volume ventilation with using FiO2 of 1.0 (OTHER), Apnea During CPB (OTHER).
Who is sponsoring clinical trial NCT04978636?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04978636 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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