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Sarcopenia clinical trials
Every US clinical trial registered for Sarcopenia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
42 US clinical trials · 16 currently recruiting
The research picture
Sarcopenia has 42 registered US clinical trials, 16 of them open to new participants right now — about 38% of the total.
- 16
- recruiting participants now
- 38%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Tufts University
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
Wake Forest University Health Sciences
NCT03998202
Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
University of California, Los Angeles
NCT04717869
Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX)
Florida Institute for Human and Machine Cognition
NCT06507189
Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans
VA Office of Research and Development
NCT04691986
Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)
Bettina Mittendorfer
NCT07083557
Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
University of North Carolina, Chapel Hill
NCT06988176
Adverse Outcomes and Mortality in Liver Transplant
Mayo Clinic
NCT05477277
Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD
The Cleveland Clinic
NCT07059637
Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)
The Cleveland Clinic
NCT04869813
The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study
Ohio State University
NCT06361511
The Influence of Movement Velocity Biofeedback on Muscle Activation and Self Perception in Older Adults With Sarcopenia
Creighton University
NCT06853275
Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment
Ohio University
NCT06828926
Strength Training and Resveratrol
Texas Tech University
NCT06585865
C-Protein in Fatigue and Aging
University of Oregon
NCT05926219
Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients
University of California, Davis
NCT06722508
Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
University of Missouri-Columbia
NCT06689618
Muscle Insulin Resistance in Aging (Mirage)
AdventHealth Translational Research Institute
NCT02230839
Electrical Stimulation of Human Myocytes in Microgravity
AdventHealth Translational Research Institute
NCT03665051
Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes
University of Maryland, Baltimore
NCT02509520
Muscle Impact of Treating Osteoporosis
Nami Safai Haeri
NCT05666310
Improving Frailty With a Rigorous Ambulation Intervention in Lung Transplant Patients
The Cleveland Clinic
NCT03636412
Efficacy of Nutritional Supplementation on Physical-activity Mediated Changes in Physical Functioning Older Adults at Risk for Mobility Disability (The VIVE2 Study)
Tufts University
NCT01542892
Improving Muscle Assessment in Older Adults - The "Can We Build a Better Mouse Trap?" Study
University of Wisconsin, Madison
NCT02295241
HORMA: Hormonal Regulators of Muscle and Metabolism in Aging
National Institute on Aging (NIA)
NCT00183040
Evaluation of the Reproducibility of Jumping Mechanography
University of Wisconsin, Madison
NCT01164670
Fish Oil and Muscle Function
Washington University School of Medicine
NCT01308957
The Urinary Incontinence Treatment Study
Wake Forest University Health Sciences
NCT03057834
Skeletal Muscle Apoptosis and Physical Performance; Oxidative RNA/DNA Damage and Repair in Aged Human Muscle
University of Florida
NCT01644279
Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults
Texas Tech University
NCT05593978
The Effect of the DASH Diet Containing Meat on Muscle and Metabolic Health in Older Adults
South Dakota State University
NCT04127240
Clinical Trial of Astaxanthin Formulation With Exercise in Sarcopenia Elderly
Astavita
NCT03368872
Evaluation of Efficacy, Tolerability, and Pharmacokinetics of MYMD1 for Chronic Inflammation and Sarcopenia/Frailty
TNF Pharmaceuticals
NCT05283486
IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial
The University of Texas Medical Branch, Galveston
NCT01869348
Biological Effects of Weight Loss In Older, Obese Women
University of Florida
NCT01032733
Role of the Gut Microbiome on Lean Mass and Physical Function in Older Adults
Tufts University
NCT02811445
A Pilot Study of the Impact of Vitamin D3 on Muscle Performance in Elderly Women
Tufts University
NCT00986596
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
Sara Espinoza
NCT03119610
Effects of Multicomponent Training in Older Adults
Geisinger Clinic
NCT06094413
The Influence of Daily Grapes Intake on Sarcopenia in Postmenopausal Women
University of California, Davis
NCT05863507
Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals
Indiana University
NCT03595774
PET/CT of Skeletal Muscle Amino Acid Kinetics
University of California, San Francis
NCT01698424
Trial of Oral Glutamine on Mitochondrial Function in CKD
University of Washington
NCT02838979
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Sarcopenia Trial Landscape
ClinicalTrials.gov lists 42 US studies indexed under Sarcopenia, and 16 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Sarcopenia shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Sarcopenia is led by Tufts University with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 42 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Sarcopenia?
PlainTrial tracks 42 US clinical trials for Sarcopenia, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Sarcopenia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.