Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Surgery: later-stage trial registry
44 of 121 indexed Surgery trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #102 of 28,707 conditions by registered trial count.
121 US clinical trials · 44 currently recruiting · #102 of 28,707 conditions by registered trial count
Surgery: 121 US clinical trials tracked, 44 recruiting.
Surgery is the subject of 121 registered US clinical trials on ClinicalTrials.gov, 44 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is University of Wisconsin, Madison, running 6 of these trials.
Enrollment posture brief
Registry condition surgery
OPEN 44 | RECR 36% | LATE 21 | EARLY 8 | RANK #102 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Acquired Brain Injury (36% recruiting · 11 trials)
Surgery lists 44 open slots (36% of 121 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Surgery on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Surgery recruits in line with its size-band peers.
44 of 121 indexed trials (36.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Surgery trials is spread across many organizations.
University of Wisconsin, Madison accounts for 6 of 121 trials (5%). 77 distinct sponsors appear on at least one study for this condition label.
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Typical Surgery enrolment sits around 100 participants.
Median target enrolment is 100 among the 121 trials that report a genuine target (sentinel values excluded). 60 of those (49.6%) plan for fewer than 100 participants.
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Surgery research is mostly interventional.
96 interventional and 25 observational studies make up this index (79.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
121 total, page 1 of 3
The Pediatric Anesthesia Quality Improvement Project
The Society for Pediatric Anesthesia
NCT00674388
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Massachusetts General Hospital
NCT07022951
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
Washington University School of Medicine
NCT05991453
Collecting Outcomes and Managing Pain After Surgery
Duke University
NCT03834818
The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery
University of Chicago
NCT03729180
RCT: Early Feeding After PEG Placement
Carilion Clinic
NCT04110613
Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury
University of Colorado, Denver
NCT06349577
Terumo Aortic Global Endovascular Registry
Vascutek
NCT04246463
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
University of Michigan
NCT05722002
Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial
University of Michigan
NCT06671002
Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)
Fox Chase Cancer Center
NCT05454280
Sentinel Node Biopsy in Endometrial Cancer
Queensland Centre for Gynaecological Cancer
NCT04073706
Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD)
Oregon Health and Science University
NCT02342444
Maestro 1.1 Post-Market Registry
Moon Surgical
NCT06103136
Evaluation of Resection Techniques for Pancreatic Tumors
Methodist Health System
NCT05128890
Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes
The Cleveland Clinic
NCT06298721
A Study of Opportunistic Salpingectomy to Prevent Ovarian Cancer
Memorial Sloan Kettering Cancer Center
NCT06312124
Prevent Cardiac Surgery Associated AKI Trial
George Washington University
NCT06620523
Music Interventions During Wide-Awake Hand Surgery
University of Wisconsin, Madison
NCT05472909
Optimizing Pain Self-Management in Total Knee Arthroplasty
University of Virginia
NCT06038240
Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery
Northwell Health
NCT07032792
Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedures
University of California, Irvine
NCT05819801
Brain Function Monitoring During Surgery
University of Chicago
NCT06619730
Methods for Effective Disposal of Surplus Analgesics to Facilitate Elimination
University of Michigan
NCT05991687
Building Resilience for Surgical Recovery
The University of Texas Health Science Center, Houston
NCT06174701
Ethyl Chloride Spray to Reduce Pain From Local Anesthesia During Mohs Micrographic Surgery
University of California, Davis
NCT06920381
Transversus Abdominis Plane Block Compared to Local Anesthetic Wound Infiltration in Gynecologic Oncology Surgery
University of Wisconsin, Madison
NCT06213454
Ultrasound Evaluation for Improving Patient Selection in vNOTES
The University of Texas Health Science Center, Houston
NCT05623514
Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
University of California, San Francisco
NCT05157113
A Study of Bevonescein in Patients Undergoing Abdominopelvic Surgery
Alume Biosciences
NCT06662097
Green Light for Post-Operative Wellness
Rebecca E Kotcher, MD
NCT07218289
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
Vanderbilt University Medical Center
NCT05774717
INCLUDE Program: A Perioperative Wellness Program Tailored for Black Surgical Patients
Washington University School of Medicine
NCT07283783
Gastric US in ICU Patient
Dartmouth-Hitchcock Medical Center
NCT05526105
AI-driven Clinical Decision Support for Perioperative Blood Orders
Washington University School of Medicine
NCT07223853
The Neuralert Stroke Monitor Pilot Trial
Neuralert Technologies
NCT06368193
Implementation Pilot of Preoperative CGA Before Major Surgery
University of Wisconsin, Madison
NCT06184724
NO During CPB in Neonates to Reduce Risk of AKI
Children's Hospital Medical Center, Cincinnati
NCT04216927
Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty
University of California, San Diego
NCT06784882
Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery
Medical University of South Carolina
NCT06451003
Physical Therapy After Endometriosis Excision
Oregon Health and Science University
NCT07127783
Geriatric Thoracic Surgery Ambulation Challenge
Dana-Farber Cancer Institute
NCT04630496
A Study of the Use of 3D Technology to Guide Head and Neck Surgery
Memorial Sloan Kettering Cancer Center
NCT06676592
LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors
University of Kansas Medical Center
NCT04979156
Operating Room Air Filtration/Sterilization
The Cleveland Clinic
NCT04610294
Perioperative Risk Study
Fox Chase Cancer Center
NCT02456389
The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial
Sunnybrook Health Sciences Centre
NCT02261415
Nudges for Opioid Reduction After Major Surgery Trial
University of Washington
NCT04927351
Insignia™ Hip Stem Outcomes Study
Stryker Orthopaedics
NCT05144191
The PASTDUe Nutrition Ecosystem Project (PASTDUe)
Duke University
NCT05127109
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 5 |
| Phase 3 | 9 |
| Phase 4 | 12 |
Top Sponsors
Named interventions
Most-linked intervention names on Surgery records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Surgery trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Surgery page
121 registered trials, 44 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 44 Surgery trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Wisconsin, Madison sponsors the most Surgery trials on record, review their full trial history before evaluating a specific study. See University of Wisconsin, Madison's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Surgery condition card totals 121 registered trials; most-linked intervention NSAID; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.