Dana-Farber Cancer Institute

819 total trials 588 currently recruiting 115 completed

Trial Pipeline

RECRUITING Phase 2

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

NCT07397611

RECRUITING Phase 2

Individualizing Approaches to Surveillance Mammography in Older Breast Cancer Survivors - The I-MAMMO Study

NCT07123649

RECRUITING NA

Feasibility Testing of a Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment (TCT)

NCT06807294

RECRUITING NA

ACT Lung Health Intervention: Phase Two

NCT06945120

RECRUITING NA

Cryocompression for CIPN

NCT07064798

RECRUITING NA

HEME Home Transfusion Program

NCT06487247

RECRUITING NA

Exercise and Nutrition for Older Cancer Survivors and Their Support Person: The Vitality Study

NCT06623097

RECRUITING NA

Sleep Treatment Education Program for Cancer Survivors: STEP-Together

NCT06736548

RECRUITING NA

Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial

NCT06923397

RECRUITING NA

BOLSTER: Learning New Skills to Thrive

NCT06936878

RECRUITING NA

Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma

NCT06831552

RECRUITING NA

Proof-of-Concept Testing of the Cardiovascular Health Equity Through Food (CHEF) Intervention in Childhood Cancer Survivors

NCT06609473

RECRUITING NA

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

NCT06716580

RECRUITING NA

Tools for Reducing Inequity in Acute Leukemia (TRIAL): Beta Testing

NCT06907797

RECRUITING NA

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Military Population: The Sentinel Study

NCT06523868

RECRUITING NA

Integrating Pain-CBT Into an mHealth Analgesic Support Intervention for Patients With Chronic Pain From Advanced Cancers

NCT06722014

RECRUITING NA

REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors

NCT06710548

RECRUITING NA

Dance Study for Post-surgical Pain in Breast Cancer Survivors

NCT06758102

RECRUITING NA

Pilot Randomized Controlled Trial of a Collaborative Agenda-setting Intervention (CASI) for Patients With Ovarian Cancer

NCT06543537

RECRUITING Phase 2

Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin

NCT06677190

RECRUITING NA

The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial

NCT06565052

RECRUITING NA

Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE)

NCT06469307

RECRUITING Early Phase 1

A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision

NCT06664151

RECRUITING Phase 1

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

NCT06475235

RECRUITING Phase 1

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

NCT06321484

RECRUITING NA

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM Study

NCT06450171

RECRUITING Phase 2

ALPINE: Maintenance Letrozole/Abemaciclib

NCT06366347

RECRUITING NA

The COMPASSION Study

NCT06507930

RECRUITING Early Phase 1

Memory-like Natural Killer (NK) Cell Therapy in Patients With Renal Cell Carcinoma or Urothelial Carcinoma

NCT06318871

RECRUITING Phase 1

Phase Ib Study of Axatilimab in Combination With Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer

NCT06488378

RECRUITING Phase 2

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

NCT06439693

RECRUITING NA

Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients

NCT06468618

RECRUITING NA

Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

NCT06202183

RECRUITING NA

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

NCT06298734

RECRUITING Phase 2

BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

NCT05922761

RECRUITING Phase 1

LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer

NCT06303713

RECRUITING NA

PediRISE Feasibility

NCT06283251

RECRUITING NA

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)

NCT06322888

RECRUITING

Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments

NCT06138561

RECRUITING Phase 1

CIML NK Cells With Venetoclax for AML

NCT06152809

RECRUITING Phase 2

RecoverPC: Relugolix vs GnRH Agonist in Quality of Life

NCT05765500

RECRUITING NA

Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial

NCT06026111

RECRUITING Phase 1

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

NCT06138587

RECRUITING NA

CV CARE: CardioVascular Care in PC Patients

NCT06202820

RECRUITING NA

Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

NCT06040125

RECRUITING NA

High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study

NCT05740839

RECRUITING Early Phase 1

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

NCT06122896

RECRUITING NA

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

NCT06038318

RECRUITING NA

A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest

NCT05899361

RECRUITING NA

Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

NCT05706766

RECRUITING Phase 2

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

NCT05726370

RECRUITING Phase 2

Pirtobrutinib and Venetoclax in Waldenström Macroglobulinemia

NCT05734495

RECRUITING NA

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

NCT05759143

RECRUITING

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

NCT05463796

RECRUITING NA

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

NCT05535192

RECRUITING NA

A Novel Intervention for Patients With Cancer

NCT05643027

RECRUITING NA

Patient-Centered Surgical Prehabilitation

NCT05715684

RECRUITING

Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

NCT05587439

RECRUITING

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

NCT05265429

RECRUITING NA

Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial

NCT05356117

RECRUITING NA

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

NCT05327465

RECRUITING NA

Video Education With Result Dependent dIsclosure

NCT05225428

RECRUITING NA

Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation

NCT05335434

RECRUITING NA

Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

NCT05236062

RECRUITING NA

Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy

NCT04997096

RECRUITING Phase 2

Zanubrutinib and Venetoclax in CLL (ZANU-VEN)

NCT05168930

RECRUITING NA

UPLYFT For Lymphoma Survivors

NCT05080166

RECRUITING NA

Resilience and Equity in Aging, Cancer, and Health (REACH)

NCT04674267

RECRUITING Phase 1

NeoVax + CDX-301 and Nivolumab or Pembrolizumab in Melanoma

NCT04930783

RECRUITING NA

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

NCT04883671

RECRUITING Phase 2

Scalp Cooling in MBC

NCT04986579

RECRUITING NA

Geriatric Thoracic Surgery Ambulation Challenge

NCT04630496

RECRUITING Phase 1

A Personalized Neoantigen Cancer Vaccine in Treatment Naïve, Asymptomatic Patients With IGHV Unmutated CLL.

NCT03219450

RECRUITING NA

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

NCT04839614

RECRUITING NA

Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy

NCT04724499

RECRUITING Phase 2

ATEMPT 2.0: Adjuvant T-DM1 vs TH

NCT04893109

RECRUITING

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

NCT04968834

RECRUITING NA

Refining Local-Regional Therapy for IBC

NCT04636710

RECRUITING Phase 1

Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer

NCT04789486

RECRUITING Phase 1

Sacituzumab Govitecan Plus EV in Metastatic UC

NCT04724018

RECRUITING Phase 1

IS-free Treg HaploHCT

NCT04678401

RECRUITING Phase 2

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer

NCT04569747

RECRUITING Phase 2

Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

NCT04620187

RECRUITING

Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress

NCT04541654

RECRUITING Phase 1

Pembrolizumab, Ibrutinib and Rituximab in PCNSL

NCT04421560

RECRUITING Phase 2

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

NCT04468061

RECRUITING Phase 2

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

NCT04434040

RECRUITING NA

Serial MRI Scans During Radiation Therapy

NCT04188535

RECRUITING NA

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

NCT04045470

RECRUITING NA

Stereotactic Magnetic Resonance Guided Radiation Therapy

NCT04115254

RECRUITING Phase 1

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

NCT04024761

RECRUITING NA

Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

NCT03875716

RECRUITING Phase 2

RESOLVE: Abemaciclib + Letrozole +/- Metformin, Zotatifin, or Gedatolisib in Endometrial or Low-Grade Serous Ovarian Cancer

NCT03675893

RECRUITING

Predicting Progression of Developing Myeloma in a High-Risk Screened Population (PROMISE)

NCT03689595

RECRUITING NA

Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers

NCT03683680

RECRUITING Phase 2

Osimertinib In EGFR Mutant Lung Cancer

NCT03586453

RECRUITING NA

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

NCT06068075

RECRUITING Phase 2

Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6

NCT03310879

RECRUITING Phase 1

Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL

NCT03319901

RECRUITING Phase 1

SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

NCT03113643

Phase Distribution

PhaseTrial count
Phase 1 133
Phase 2 196
Phase 3 3

What the Pipeline for Dana-Farber Cancer Institute Shows

According to the ClinicalTrials.gov registry, Dana-Farber Cancer Institute is linked to 819 US clinical trials across every stage of research activity. Of those, 588 studies are currently recruiting — about 72% of the sponsor's indexed portfolio — and 115 are already marked complete, representing roughly 14% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Dana-Farber Cancer Institute reports 3 late-stage studies (Phase 3 and Phase 4 combined) and 329 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Dana-Farber Cancer Institute is Breast Cancer with 53 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial