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NCT04084548 · ClinicalTrials.gov registry record · Phase 3
Perioperative Lidocaine and Ketamine in Abdominal Surgery
A Phase 3 study of Postoperative Pain, sponsored by The Cleveland Clinic.
- Active
- Registry status
- Phase 3
- Development phase
- 420
- Enrollment target
- 1
- Study location
NCT04084548: Active Phase 3 study of Postoperative Pain, sponsored by The Cleveland Clinic.
NCT04084548 is a Phase 3 study of Postoperative Pain that is active but no longer recruiting, run by The Cleveland Clinic. The registered enrollment target is 420 participants, above the 228-participant average among 120 other Postoperative Pain trials with a reported enrollment target (84% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04084548, a Phase 3 study of Postoperative Pain, is active but no longer recruiting, sponsored by The Cleveland Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 420 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators propose to test the hypothesis that perioperative infusions of lidocaine and/or ketamine reduce opioid consumption and pain scores in adults recovering from elective inpatient abdominal surgery.
Primary Outcome
Pain scores based on the visual analog scale and Brief Pain Inventory. Ranges from 0 to 10, with 0 being no pain and 10 being the worst imaginable pain. The intervention will be deemed effective if both outcomes are non-inferior, and at least one is superior, to the control group.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Ketamine
- DRUG Lidocaine
- DRUG Lidocaine and ketamine
Study Locations (1)
Florida
- Cleveland Clinic Florida - Weston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 420 participants |
| Start Date | 2019-10-15 |
| Est. Completion | 2025-12 |
| Phase | Phase 3 |
What the registry record for NCT04084548 still lists
NCT04084548 is an interventional study that assigns participants to a tested intervention. The registered 420 participants enrollment target is mid-sized for trials with a published cap, above the 228-participant average among 120 other Postoperative Pain trials with a reported enrollment target (84% higher).
The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT04084548 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT04084548 about?
NCT04084548 is a clinical study titled "Perioperative Lidocaine and Ketamine in Abdominal Surgery". The investigators propose to test the hypothesis that perioperative infusions of lidocaine and/or ketamine reduce opioid consumption and pain scores in adults recovering from elective inpatient abdominal surgery.
What is the current status of trial NCT04084548?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 420 participants. The study started on 2019-10-15. Estimated completion is 2025-12.
What conditions does trial NCT04084548 study?
This clinical trial studies the following conditions: Postoperative Pain.
What interventions are being tested in trial NCT04084548?
The interventions under investigation include: Placebo (DRUG), Ketamine (DRUG), Lidocaine (DRUG), Lidocaine and ketamine (DRUG).
Who is sponsoring clinical trial NCT04084548?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04084548 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04084548's enrollment target sits among peer trials
420 11th of 120 higher than 110 of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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