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NCT06344143 · ClinicalTrials.gov registry record
Detecting Mild Autonomous Cortisol Secretion in Patients With Adrenal Incidentaloma
A clinical trial of Mild Autonomous Cortisol Secretion (MACS), sponsored by The Cleveland Clinic.
- Recruiting
- Registry status
- 20
- Enrollment target
- 1
- Study location
NCT06344143: Recruiting study of Mild Autonomous Cortisol Secretion (MACS), sponsored by The Cleveland Clinic.
NCT06344143 is a study of Mild Autonomous Cortisol Secretion (MACS) that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 20 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06344143, a study of Mild Autonomous Cortisol Secretion (MACS), is actively recruiting participants, sponsored by The Cleveland Clinic.
- RECRUITING
- Registry status
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of the proposed study is to estimate the incidence of Mild Autonomous Cortisol Secretion (MACS) in patients with Adrenal Incidentaloma (AI) and evaluate the available diagnostic tests to determine the most sensitive and specific combination of tests for assessing MACS from adrenal adenoma for prediction of the phenotype associated with cortisol excess. As well as following the patients for 4 years and see if anything changes.
Primary Outcome
To evaluate and determine the most sensitive and specific combination of tests for assessing mild autonomous cortisol secreting (MACS) from adrenal adenoma for prediction of the phenotype associated with cortisol excess. Study team will measure cortisol in serum, cortisol in saliva, cortisol in urine, vasopressin stimulation test, 1 mg dexamethasone stimulation test (DST) and a 2 mg DST, Adrenocorticotropic Hormone test (ACTH) and (dehydroepiandrosterone sulfate test) DHEAS. With this, a diagnos
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Various labs and imaging tests
Study Locations (1)
Ohio
- The Cleveland Clinic Foundation - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-11-20 |
| Est. Completion | 2030-12-31 |
What NCT06344143 shows while recruiting
NCT06344143 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 1 condition, with Mild Autonomous Cortisol Secretion (MACS) appearing as the primary indexed condition, and to 1 intervention - of which Various labs and imaging tests is the first listed.
NCT06344143 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06344143 about?
NCT06344143 is a clinical study titled "Detecting Mild Autonomous Cortisol Secretion in Patients With Adrenal Incidentaloma". The aim of the proposed study is to estimate the incidence of Mild Autonomous Cortisol Secretion (MACS) in patients with Adrenal Incidentaloma (AI) and evaluate the available diagnostic tests to determine the most sensitive and specific combination of tests for assessing MACS from adrenal adenoma fo...
What is the current status of trial NCT06344143?
This trial is currently recruiting. The enrollment target is 20 participants. The study started on 2024-11-20. Estimated completion is 2030-12-31.
What conditions does trial NCT06344143 study?
This clinical trial studies the following conditions: Mild Autonomous Cortisol Secretion (MACS).
What interventions are being tested in trial NCT06344143?
The interventions under investigation include: Various labs and imaging tests (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06344143?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06344143 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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