Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07127354 · ClinicalTrials.gov registry record · Phase 4
The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality
A Phase 4 study of GLP-1 and Bowel Preparation for Colonoscopy, sponsored by The Cleveland Clinic.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 132
- Enrollment target
- 3
- Study locations
NCT07127354: Recruiting Phase 4 study of GLP-1 and Bowel Preparation for Colonoscopy, sponsored by The Cleveland Clinic.
NCT07127354 is a Phase 4 study of GLP-1 and Bowel Preparation for Colonoscopy that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 132 participants, above the 83-participant average among 7 other GLP-1 trials with a reported enrollment target (59% higher). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07127354, a Phase 4 study of GLP-1 and Bowel Preparation for Colonoscopy, is actively recruiting participants, sponsored by The Cleveland Clinic.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 132 participants
- Enrollment target
- 3
- Study locations
Study Summary
The goal of this clinical trial is to learn how GLP-1 and GIP agonists effect bowel preparation in patients scheduled for colonoscopies. The main questions it aims to answer are: * Does GLP-1 and GIP agonist increase the rate of inadequate bowel preparation? * Does the quality of bowel preparation differ in patients who hold vs. those who continue a single dose of their GLP-1 or GIP agonist medication? * Are there any differences in the rates of complications gastric aspiration in patients who hold vs. continue a single dose of their GLP-1 or GIP agonist medication?
Conditions Studied
Interventions
- DRUG Continue GLP/GIP
Study Locations (3)
Florida
- Cleveland Clinic - Cleveland
- Cleveland Clinic - Cleveland
- Cleveland Clinic Weston - Weston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 132 participants |
| Start Date | 2025-08-01 |
| Est. Completion | 2026-08 |
| Phase | Phase 4 |
What NCT07127354 shows while recruiting
NCT07127354 is an interventional study that assigns participants to a tested intervention. The registered 132 participants enrollment target is mid-sized for trials with a published cap, above the 83-participant average among 7 other GLP-1 trials with a reported enrollment target (59% higher).
The record links to 2 conditions, with GLP-1 appearing as the primary indexed condition, and to 1 intervention - of which Continue GLP/GIP is the first listed.
NCT07127354 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT07127354 about?
NCT07127354 is a clinical study titled "The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality". The goal of this clinical trial is to learn how GLP-1 and GIP agonists effect bowel preparation in patients scheduled for colonoscopies. The main questions it aims to answer are: * Does GLP-1 and GIP agonist increase the rate of inadequate bowel preparation? * Does the quality of bowel preparation ...
What is the current status of trial NCT07127354?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 132 participants. The study started on 2025-08-01. Estimated completion is 2026-08.
What conditions does trial NCT07127354 study?
This clinical trial studies the following conditions: GLP-1, Bowel Preparation for Colonoscopy.
What interventions are being tested in trial NCT07127354?
The interventions under investigation include: Continue GLP/GIP (DRUG).
Who is sponsoring clinical trial NCT07127354?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07127354 being conducted?
This trial has 3 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for GLP-1
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
RECRUITING · Phase 4
-
MAINTAIN (Mucosal AblatIoN Therapy After INcretins)
RECRUITING · NA
-
GLP-1RA Effects on Lean Mass and Bone Health in Midlife Women
RECRUITING
-
A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Supplement on Nutrient Gaps and Gut Health Among Individuals Utilizing GLP-1 RAs
RECRUITING · NA
-
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
RECRUITING · Phase 2
-
Bone Metabolism in 12-21 Year Olds Undergoing GLP-1 Receptor Agonist Therapy
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01766297 · 132 participants · Phase 2
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
- NCT04002947 · 132 participants · Phase 2
Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma
- NCT04128189 · 132 participants · Phase 3
Shingrix in Renal Transplant Recipients
- NCT04199780 · 132 participants · NA
Effects of tDCS Combined With CBI on Postsurgical Pain
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI