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NCT07127354 · ClinicalTrials.gov registry record · Phase 4

The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality

A Phase 4 study of GLP-1 and Bowel Preparation for Colonoscopy, sponsored by The Cleveland Clinic.

Recruiting
Registry status
Phase 4
Development phase
132
Enrollment target
3
Study locations

NCT07127354 is a Phase 4 study of GLP-1 and Bowel Preparation for Colonoscopy that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 132 participants, above the 83-participant average among 7 other GLP-1 trials with a reported enrollment target (59% higher). The trial reports 3 study locations across 1 state.

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The verdict

NCT07127354, a Phase 4 study of GLP-1 and Bowel Preparation for Colonoscopy, is actively recruiting participants, sponsored by The Cleveland Clinic.

RECRUITING
Registry status
Phase 4
Development phase
132 participants
Enrollment target
3
Study locations

Study Summary

The goal of this clinical trial is to learn how GLP-1 and GIP agonists effect bowel preparation in patients scheduled for colonoscopies. The main questions it aims to answer are: * Does GLP-1 and GIP agonist increase the rate of inadequate bowel preparation? * Does the quality of bowel preparation differ in patients who hold vs. those who continue a single dose of their GLP-1 or GIP agonist medication? * Are there any differences in the rates of complications gastric aspiration in patients who hold vs. continue a single dose of their GLP-1 or GIP agonist medication?

Conditions Studied

GLP-1 Bowel Preparation for Colonoscopy

Interventions

  • DRUG Continue GLP/GIP

Study Locations (3)

Florida

  • Cleveland Clinic - Cleveland
  • Cleveland Clinic - Cleveland
  • Cleveland Clinic Weston - Weston

Trial Details

FieldValue
Enrollment Target 132 participants
Start Date 2025-08-01
Est. Completion 2026-08
Phase Phase 4

Sponsor

The Cleveland Clinic

688 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07127354

The ClinicalTrials.gov registry entry for NCT07127354 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 132 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 83-participant average among 7 other GLP-1 trials with a reported enrollment target (59% higher). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with GLP-1 appearing as the primary indexed condition, and to 1 intervention - of which Continue GLP/GIP is the first listed.

NCT07127354 reports 3 study locations spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT07127354 about?

NCT07127354 is a clinical study titled "The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality". The goal of this clinical trial is to learn how GLP-1 and GIP agonists effect bowel preparation in patients scheduled for colonoscopies. The main questions it aims to answer are: * Does GLP-1 and GIP agonist increase the rate of inadequate bowel preparation? * Does the quality of bowel preparation ...

What is the current status of trial NCT07127354?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 132 participants. The study started on 2025-08-01. Estimated completion is 2026-08.

What conditions does trial NCT07127354 study?

This clinical trial studies the following conditions: GLP-1, Bowel Preparation for Colonoscopy.

What interventions are being tested in trial NCT07127354?

The interventions under investigation include: Continue GLP/GIP (DRUG).

Who is sponsoring clinical trial NCT07127354?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07127354 being conducted?

This trial has 3 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.