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NCT07315204 · ClinicalTrials.gov registry record

Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion

A clinical trial of Liver Transplant Disorder, sponsored by The Cleveland Clinic.

Recruiting
Registry status
850
Enrollment target
1
Study location

NCT07315204 is a study of Liver Transplant Disorder that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 850 participants, above the 28-participant average among 3 other Liver Transplant Disorder trials with a reported enrollment target (2936% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT07315204, a study of Liver Transplant Disorder, is actively recruiting participants, sponsored by The Cleveland Clinic.

RECRUITING
Registry status
850 participants
Enrollment target
1
Study location

Study Summary

Discarded perfusate samples will be collected from donors after circulatory death (DCD) or donors after brain death (DBD) organs during the machine perfusion period prior to transplantation by the study team. FMN will be measured as is standard of care for all machine perfusion liver transplant cases at Cleveland Clinic. Participating centers will be provided with sample collection and shipping instructions to ensure sample preservation in accordance with IATA guidelines. Samples from outside sites will not be stored for future research and will be discarded once analysis is completed. After the collection of the samples from machine perfusion, the transplant procedure will continue according to standard process.

Conditions Studied

Study Locations (1)

Ohio

  • Cleveland Clinic Foundation - Cleveland

Trial Details

FieldValue
Enrollment Target 850 participants
Start Date 2025-12-29
Est. Completion 2028-12-31

Sponsor

The Cleveland Clinic

688 total trials

What the Registry Record Tells You About NCT07315204

The ClinicalTrials.gov registry entry for NCT07315204 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 850 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 28-participant average among 3 other Liver Transplant Disorder trials with a reported enrollment target (2936% higher). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Liver Transplant Disorder appearing as the primary indexed condition, and to 0 interventions.

NCT07315204 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT07315204 about?

NCT07315204 is a clinical study titled "Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion". Discarded perfusate samples will be collected from donors after circulatory death (DCD) or donors after brain death (DBD) organs during the machine perfusion period prior to transplantation by the study team. FMN will be measured as is standard of care for all machine perfusion liver transplant case...

What is the current status of trial NCT07315204?

This trial is currently recruiting. The enrollment target is 850 participants. The study started on 2025-12-29. Estimated completion is 2028-12-31.

What conditions does trial NCT07315204 study?

This clinical trial studies the following conditions: Liver Transplant Disorder.

Who is sponsoring clinical trial NCT07315204?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07315204 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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