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NCT06973785 · ClinicalTrials.gov registry record · Phase 3
Non-Narcotic Pain Control After ACL Reconstruction
A Phase 3 study of ACL Injuries and ACL - Anterior Cruciate Ligament Rupture, sponsored by The Cleveland Clinic.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 30
- Enrollment target
- 3
- Study locations
NCT06973785: Recruiting Phase 3 study of ACL Injuries and ACL - Anterior Cruciate Ligament Rupture, sponsored by The Cleveland Clinic.
NCT06973785 is a Phase 3 study of ACL Injuries and ACL - Anterior Cruciate Ligament Rupture that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 30 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (96% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06973785, a Phase 3 study of ACL Injuries and ACL - Anterior Cruciate Ligament Rupture, is actively recruiting participants, sponsored by The Cleveland Clinic.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 30 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing primary knee ACL reconstruction outpatient surgery.
Primary Outcome
How many narcotic pills were consumed
Conditions Studied
Interventions
- DRUG dispense of study drug
- DRUG Ketorolac
Study Locations (3)
Ohio
- Cleveland clinic sports medicine - Garfield
- Cleveland Clinic - Strongsville
Florida
- Cleveland Clinic Coral Springs - Coral Springs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-07-15 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 3 |
What NCT06973785 shows while recruiting
NCT06973785 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with ACL Injuries appearing as the primary indexed condition, and to 2 interventions - of which dispense of study drug is the first listed.
NCT06973785 reports a single indexed study location in Ohio, Florida.
Frequently Asked Questions
What is clinical trial NCT06973785 about?
NCT06973785 is a clinical study titled "Non-Narcotic Pain Control After ACL Reconstruction". This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narco...
What is the current status of trial NCT06973785?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 30 participants. The study started on 2025-07-15. Estimated completion is 2026-12-31.
What conditions does trial NCT06973785 study?
This clinical trial studies the following conditions: ACL Injuries, ACL - Anterior Cruciate Ligament Rupture.
What interventions are being tested in trial NCT06973785?
The interventions under investigation include: dispense of study drug (DRUG), Ketorolac (DRUG).
Who is sponsoring clinical trial NCT06973785?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06973785 being conducted?
This trial has 3 study locations across Florida, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for ACL Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06973785's enrollment target sits among peer trials
30 1918th of 2000 higher than 68 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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