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NCT07680283 · ClinicalTrials.gov registry record · NA
Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD
A NA study, sponsored by The Cleveland Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 44
- Enrollment target
NCT07680283: Recruiting NA study, sponsored by The Cleveland Clinic.
NCT07680283 is a NA study that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 44 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07680283, a NA study, is actively recruiting participants, sponsored by The Cleveland Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 44 participants
- Enrollment target
Study Summary
This is a Phase II, single-center (Cleveland Clinic), two-arm, randomized, parallel-group superiority trial. The two arms will compare IOUS-guided margin selection against standard macroscopic margin selection in patients undergoing ileocolic resection for terminal ileal Crohn's disease. Patients and outcome assessors (pathologists, endoscopists) will be blinded to the intervention arm, while surgeons, by the nature of the intervention, cannot be blinded. Randomization will be computer-generated with concealed allocation using permuted blocks to ensure balanced group sizes.
Primary Outcome
Feasibility, defined as the proportion of cases in which IOUS is successfully performed with a designated proximal margin (Margin B) in the IOUS arm, will be reported as a percentage with 95% confidence intervals. Feasibility will be declared if ≥ 75% of randomized patients in the IOUS arm achieve successful designation of Margin B. Failure will be defined as such: Technical inability to measure bowel wall thickness with ultrasound or to stratify the bowel wall stratification; failure to identif
Interventions
- DEVICE IOUS-guided margin selection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2026-07 |
| Est. Completion | 2029-01 |
| Phase | NA |
What NCT07680283 shows while recruiting
NCT07680283 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which IOUS-guided margin selection is the first listed.
NCT07680283 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07680283 about?
NCT07680283 is a clinical study titled "Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD". This is a Phase II, single-center (Cleveland Clinic), two-arm, randomized, parallel-group superiority trial. The two arms will compare IOUS-guided margin selection against standard macroscopic margin selection in patients undergoing ileocolic resection for terminal ileal Crohn's disease. Patients an...
What is the current status of trial NCT07680283?
This trial is currently recruiting. It is a NA study. The enrollment target is 44 participants. The study started on 2026-07. Estimated completion is 2029-01.
What interventions are being tested in trial NCT07680283?
The interventions under investigation include: IOUS-guided margin selection (DEVICE).
Who is sponsoring clinical trial NCT07680283?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07680283's enrollment target sits among peer trials
44 1423rd of 2000 higher than 566 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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