Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06795035 · ClinicalTrials.gov registry record
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution
A clinical trial of Coronary Microvascular Dysfunction and ST Elevation Myocardial Infarction, sponsored by The Cleveland Clinic.
- Recruiting
- Registry status
- 70
- Enrollment target
- 1
- Study location
NCT06795035: Recruiting study of Coronary Microvascular Dysfunction and ST Elevation Myocardial Infarction, sponsored by The Cleveland Clinic.
NCT06795035 is a study of Coronary Microvascular Dysfunction and ST Elevation Myocardial Infarction that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 70 participants, below the 262-participant average among 7 other Coronary Microvascular Dysfunction trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06795035, a study of Coronary Microvascular Dysfunction and ST Elevation Myocardial Infarction, is actively recruiting participants, sponsored by The Cleveland Clinic.
- RECRUITING
- Registry status
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study to measure the heart's microvascular function in the setting of a myocardial infarction (MI), or heart attack, using a method called continuous saline thermodilution (CST). The participants will include people who are experiencing MI from sudden and complete blockage of a coronary artery requiring immediate balloon and/or stent therapy. After getting the balloon and/or stent therapy, participants will have their heart's microvascular system tested using CST. The main questions it aims to answer are: * What measurements using CST can we expect from the heart's microvascular system during a treated MI? * Can CST measurements during a treated MI predict the amount of heart muscle that is injured and that recovers? For this study, participants will undergo measurement of their heart's microvascular function after balloon and/or stent therapy for the MI. They will then receive an MRI scan of the heart several days after the MI.
Primary Outcome
Calculated index to assess coronary microvascular dysfunction (Q\_hyperemia/Q\_rest)\*(Pa\_rest/Pd\_hyperemia)
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Continuous Saline Thermodilution
Study Locations (1)
Ohio
- Cleveland Clinic - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2025-05-29 |
| Est. Completion | 2027-12-31 |
What NCT06795035 shows while recruiting
NCT06795035 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 262-participant average among 7 other Coronary Microvascular Dysfunction trials with a reported enrollment target (73% lower).
The record links to 3 conditions, with Coronary Microvascular Dysfunction appearing as the primary indexed condition, and to 1 intervention - of which Continuous Saline Thermodilution is the first listed.
NCT06795035 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06795035 about?
NCT06795035 is a clinical study titled "Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution". The goal of this observational study to measure the heart's microvascular function in the setting of a myocardial infarction (MI), or heart attack, using a method called continuous saline thermodilution (CST). The participants will include people who are experiencing MI from sudden and complete bloc...
What is the current status of trial NCT06795035?
This trial is currently recruiting. The enrollment target is 70 participants. The study started on 2025-05-29. Estimated completion is 2027-12-31.
What conditions does trial NCT06795035 study?
This clinical trial studies the following conditions: Coronary Microvascular Dysfunction, ST Elevation Myocardial Infarction, Microvascular Obstruction.
What interventions are being tested in trial NCT06795035?
The interventions under investigation include: Continuous Saline Thermodilution (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06795035?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06795035 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Coronary Microvascular Dysfunction
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Improving Coronary Vascular Health in Women
RECRUITING · Phase 2
-
Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF
RECRUITING
-
A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD
RECRUITING
-
Coronary Microvascular Disease (CMD) Registry
RECRUITING
-
The DISCOVER INOCA Prospective Multi-center Registry
ACTIVE NOT RECRUITING
-
Safety and Potential Bioactivity of CLBS16 in Patients With Coronary Microvascular Dysfunction and Without Obstructive Coronary Artery Disease
COMPLETED · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00969111 · 70 participants · NA
Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy
- NCT01712620 · 70 participants · Phase 2
Spironolactone for Pulmonary Arterial Hypertension
- NCT02143830 · 70 participants · Phase 2
HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
- NCT02601339 · 70 participants
NIRS Monitoring in Premature Infants
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI