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NCT06849752 · ClinicalTrials.gov registry record

Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF

A clinical trial of Heart Failure and Socioeconomic Adversity, sponsored by The Cleveland Clinic.

Recruiting
Registry status
1,000
Enrollment target
1
Study location

NCT06849752 is a study of Heart Failure and Socioeconomic Adversity that is actively recruiting participants, run by The Cleveland Clinic. The registered enrollment target is 1,000 participants, below the 2,047-participant average among 397 other Heart Failure trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06849752, a study of Heart Failure and Socioeconomic Adversity, is actively recruiting participants, sponsored by The Cleveland Clinic.

RECRUITING
Registry status
1,000 participants
Enrollment target
1
Study location

Study Summary

EAGLE-HF (Early Assessment and initiation of GuideLine-directed Evidence-based management-HF) is a prospective single site study of a multinational, unblinded, randomized-controlled, longitudinal trial called SYMPHONY. Primary, secondary and exploratory outcomes that are part of SYMPHONY are not described herein as they replicate SYMPHONY outcomes. Data associated with SYMPHONY outcomes will be sent to the SYMPHONY coordinating center. In EAGLE-HF, site investigators will examine if a new-onset heart failure (HF) diagnosis are asscoiated with social determinants of health (6 factors), social vulnerability index and distressed community indices. In addition, for patients diagnosed with HFrEF, prescribing patterns (use of and dose of) core HF medications will be assessed for association with physician practice type and medical provider type. Finally, (among participants in the SYMPHONY Active arm, an optimal NTproBNP cut-point will be assessed for diagnosis of HF based on social determinants of health, social vulnerability index, distressed community index, HF risk factors and medical comorbidities.

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 1,000 participants
Start Date 2025-03-11
Est. Completion 2031-12

Sponsor

The Cleveland Clinic

688 total trials

What the Registry Record Tells You About NCT06849752

The ClinicalTrials.gov registry entry for NCT06849752 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,047-participant average among 397 other Heart Failure trials with a reported enrollment target (51% lower). The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 0 interventions.

NCT06849752 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT06849752 about?

NCT06849752 is a clinical study titled "Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF". EAGLE-HF (Early Assessment and initiation of GuideLine-directed Evidence-based management-HF) is a prospective single site study of a multinational, unblinded, randomized-controlled, longitudinal trial called SYMPHONY. Primary, secondary and exploratory outcomes that are part of SYMPHONY are not des...

What is the current status of trial NCT06849752?

This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2025-03-11. Estimated completion is 2031-12.

What conditions does trial NCT06849752 study?

This clinical trial studies the following conditions: Heart Failure, Socioeconomic Adversity.

Who is sponsoring clinical trial NCT06849752?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06849752 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.