Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00084162 · ClinicalTrials.gov registry record
Neurocardiac Control in Major Depression
A clinical trial of Depression, Involutional, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 41
- Enrollment target
- 1
- Study location
NCT00084162 is a study of Depression, Involutional that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 41 participants. The trial reports 1 study location across 1 state.
The verdict
NCT00084162, a study of Depression, Involutional, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 41 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine how depression may influence the way the brain regulates heart function. Some researchers believe that depression may be a risk factor for some forms of heart disease. Right-handed healthy volunteers and patients with major depressive disorder who are between 18 and 50 years of age may be eligible for this study. Female candidates must be premenopausal. Patients must currently be experiencing a major depressive episode. All candidates are screened with a medical history and physical examination, electrocardiogram, and blood and urine tests. They are interviewed about their psychiatric and medical history, current emotional state and sleep pattern, and family history of psychiatric disorders. They complete symptoms ratings scales for depression, anxiety, and negative thinking; history of alcohol and tobacco use; level of physical activity; socioeconomic status; overall level of functioning; and, for depressed patients, their depression type. Women candidates have their menstrual phase determined by the timing of their recent menstrual cycles and may undergo testing to determine the time of their ovulation. Participants undergo the following tests and procedures: * 12-minute walk/run test - This test measures the subject's general level of cardiorespiratory fitness. In a gymnasium in the NIH Clinical Center, the subject walks or runs as far as he or she can in 12 minutes. Blood pressure is measured before and after the exercise test, and heart rate is measured during exercise with a monitor worn around the chest. * Magnetic resonance imaging (MRI) - A brain MRI scan is done to obtain pictures of the brain anatomy. Electrocardiogram leads are placed on the subject's chest to measure the electrical activity of the heart during the scanning session. The subject lies on a narrow bed in the scanner, which is a narrow metal cylinder about 6 feet long. The scanning session takes up to 90 minutes. * Positron emission tomography (PET) - PET scanning
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2004-03-30 |
| Est. Completion | 2010-03-17 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00084162
The ClinicalTrials.gov registry entry for NCT00084162 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Depression, Involutional appearing as the primary indexed condition, and to 0 interventions.
NCT00084162 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00084162 about?
NCT00084162 is a clinical study titled "Neurocardiac Control in Major Depression". This study will examine how depression may influence the way the brain regulates heart function. Some researchers believe that depression may be a risk factor for some forms of heart disease. Right-handed healthy volunteers and patients with major depressive disorder who are between 18 and 50 years...
What is the current status of trial NCT00084162?
This trial is currently completed. The enrollment target is 41 participants. The study started on 2004-03-30. Estimated completion is 2010-03-17.
What conditions does trial NCT00084162 study?
This clinical trial studies the following conditions: Depression, Involutional.
Who is sponsoring clinical trial NCT00084162?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00084162 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.