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NCT00369798 · ClinicalTrials.gov registry record · Phase 1
Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients
A Phase 1 study of Healthy and Major Depressive Disorder, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- Phase 1
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT00369798 is a Phase 1 study of Healthy and Major Depressive Disorder that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 100 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00369798, a Phase 1 study of Healthy and Major Depressive Disorder, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary purpose of this protocol is to compare PDE4 levels before and after starting a selective serotonin reuptake inhibitor (SSRI) sertraline, citalopram or escitalopram in unmedicated depressed patients. The secondary purpose is to compare PDE4 levels between unmedicated depressed patients and healthy subjects.
Conditions Studied
Interventions
- PROCEDURE PET scan
- DRUG Rolipram
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2006-08-02 |
| Est. Completion | 2016-10-12 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00369798
The ClinicalTrials.gov registry entry for NCT00369798 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (85% lower). The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which PET scan is the first listed.
NCT00369798 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00369798 about?
NCT00369798 is a clinical study titled "Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients". The primary purpose of this protocol is to compare PDE4 levels before and after starting a selective serotonin reuptake inhibitor (SSRI) sertraline, citalopram or escitalopram in unmedicated depressed patients. The secondary purpose is to compare PDE4 levels between unmedicated depressed patients an...
What is the current status of trial NCT00369798?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2006-08-02. Estimated completion is 2016-10-12.
What conditions does trial NCT00369798 study?
This clinical trial studies the following conditions: Healthy, Major Depressive Disorder.
What interventions are being tested in trial NCT00369798?
The interventions under investigation include: PET scan (PROCEDURE), Rolipram (DRUG).
Who is sponsoring clinical trial NCT00369798?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00369798 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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