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NCT00105118 · ClinicalTrials.gov registry record
Effect of Transcranial Magnetic Stimulation on Memory
A clinical trial, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 80
- Enrollment target
NCT00105118 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 80 participants.
The verdict
NCT00105118 has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 80 participants
- Enrollment target
Study Summary
This study will examine the effect of transcranial magnetic stimulation (TMS) on short-term memory in healthy adults. Healthy people use their brains to answer short-term memory questions in a different way than do patients with schizophrenia. Attention and memory deficits in schizophrenia patients significantly hamper their recovery and rehabilitation, yet there are no effective treatments for these impairments. TMS is a method of brain stimulation that may be able to change the electrical activity of the nerve cells of the brain and improve certain brain functions. This study will explore the effect of TMS on memory and perhaps discover brain processes that may be helpful in developing new ways to treat schizophrenia. Healthy volunteers between 18 and 55 years of age, excluding pregnant women, may be eligible for this study. Participants undergo the following tests and procedures: * Medical history, physical examination, blood tests, electrocardiogram (EKG), and urine pregnancy test for women of childbearing age. * Magnetic resonance imaging (MRI) and functional MRI (fMRI). These tests are done in participants who have not had structural and functional MRIs as participants in NIMH's 2-day schizophrenia study within 90 days of entering the current study. MRI is done to locate the place in the brain to simulate with TMS and fMRI is done to look at brain activity while the subject solves short-term memory tasks. Both tests are done at the same session. Before the scan, four vitamin E capsules are taped to the subject's scalp. After the capsules are in place, the subject lies on a stretcher that is moved into the scanner - a narrow cylinder with a strong magnetic field. During the scan, subjects are asked to do some simple tests, such as watching pictures on a screen or pressing buttons in response to numbers they were shown a few seconds earlier. Scanning may take up to 2 hours, but usually lasts between 45 and 90 minutes. * TMS. For this procedure, subjects receiv
Interventions
- DEVICE Magstim Super Rapid Magnetic Stimulator
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2005-03 |
| Est. Completion | 2006-02 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00105118
The ClinicalTrials.gov registry entry for NCT00105118 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Magstim Super Rapid Magnetic Stimulator is the first listed.
NCT00105118 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00105118 about?
NCT00105118 is a clinical study titled "Effect of Transcranial Magnetic Stimulation on Memory". This study will examine the effect of transcranial magnetic stimulation (TMS) on short-term memory in healthy adults. Healthy people use their brains to answer short-term memory questions in a different way than do patients with schizophrenia. Attention and memory deficits in schizophrenia patients ...
What is the current status of trial NCT00105118?
This trial is currently completed. The enrollment target is 80 participants. The study started on 2005-03. Estimated completion is 2006-02.
What interventions are being tested in trial NCT00105118?
The interventions under investigation include: Magstim Super Rapid Magnetic Stimulator (DEVICE).
Who is sponsoring clinical trial NCT00105118?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
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