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NCT00060775 · ClinicalTrials.gov registry record
The Psychobiology of Childhood Temperament
A clinical trial, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 550
- Enrollment target
NCT00060775: Completed study, sponsored by National Institute of Mental Health (NIMH).
NCT00060775 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 550 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00060775 has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 550 participants
- Enrollment target
Study Summary
The purpose of this study is to use brain imaging technology to examine brain changes that occur in children when they are exposed to various kinds of emotional tasks and to determine if these changes are related to the child's temperament. Studies suggest that the risk for developing mood and anxiety disorders in preschool children may be linked to differences in temperament. The relationship between temperament and risk or resilience may reflect the influences of brain activity on behavior at different stages of childhood development. Behavioral inhibition and mood or anxiety disorders have been linked to disturbances in the circuitry of several areas in the brain. However, the involvement of this circuitry in temperament remains unclear. This study will use functional magnetic resonance imaging (fMRI) to examine the function of different parts of the brain in children who have previously undergone temperament studies and have had their temperaments classified. Two sets of studies will be performed in the current protocol. A small set of pilot studies will be performed in infants, by staff at the University of Maryland. In terms of the studies among infants, these subjects will initially be contacted by staff at Maryland and then will be seen at the NIH for up to three visits lasting between 4- to 5- hours during the first year of life. These subjects also will undergo visits at the University of Maryland throughout the first year of life. This study will comprise up to four clinic visits. At Visit 1, children and their parents will meet with study staff individually and together for psychiatric interviews. Children will undergo a physical examination, medical history, a urine drug test, and practice in an fMRI simulator. Saliva samples will be collected from the children and tests will be given to assess stage of puberty, temperament, intelligence, feelings, experiences, and behavior. Other visits include fMRI scans of the brain and other tasks.
Primary Outcome
Task performance on paradigms used in the scanner or in the clinic
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 550 participants |
| Start Date | 2003-11-10 |
What the finished NCT00060775 record still lists
NCT00060775 is an observational study that tracks outcomes without assigning an intervention. The registered 550 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00060775 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00060775 about?
NCT00060775 is a clinical study titled "The Psychobiology of Childhood Temperament". The purpose of this study is to use brain imaging technology to examine brain changes that occur in children when they are exposed to various kinds of emotional tasks and to determine if these changes are related to the child's temperament. Studies suggest that the risk for developing mood and anxi...
What is the current status of trial NCT00060775?
This trial is currently completed. The enrollment target is 550 participants. The study started on 2003-11-10.
Who is sponsoring clinical trial NCT00060775?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
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