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NCT00375843 · ClinicalTrials.gov registry record · Phase 4

Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication

A Phase 4 study, sponsored by National Institute of Mental Health (NIMH).

Completed
Registry status
Phase 4
Development phase
118
Enrollment target

NCT00375843: Completed Phase 4 study, sponsored by National Institute of Mental Health (NIMH).

NCT00375843 is a Phase 4 study that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 118 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00375843, a Phase 4 study, has completed, sponsored by National Institute of Mental Health (NIMH).

COMPLETED
Registry status
Phase 4
Development phase
118 participants
Enrollment target

Study Summary

This study will examine how brain activity is affected by antidepressant treatment and how changes in brain activity relate to treatment response in people with depression.

Interventions

  • DRUG Escitalopram
  • DRUG Sertraline

Trial Details

FieldValue
Enrollment Target 118 participants
Start Date 2005-01
Est. Completion 2008-03
Phase Phase 4

What the finished NCT00375843 record still lists

NCT00375843 is an interventional study that assigns participants to a tested intervention. The registered 118 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 2 interventions - of which Escitalopram is the first listed.

NCT00375843 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00375843 about?

NCT00375843 is a clinical study titled "Brain Activity Changes and Treatment Response in Depressed People Who Are Receiving Antidepressant Medication". This study will examine how brain activity is affected by antidepressant treatment and how changes in brain activity relate to treatment response in people with depression.

What is the current status of trial NCT00375843?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 118 participants. The study started on 2005-01. Estimated completion is 2008-03.

What interventions are being tested in trial NCT00375843?

The interventions under investigation include: Escitalopram (DRUG), Sertraline (DRUG).

Who is sponsoring clinical trial NCT00375843?

This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00375843's enrollment target sits among peer trials

118 713th of 2000 higher than 1,287 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00375843, the US trial registry maintained by the National Library of Medicine. NCT00375843 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.