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NCT00083629 · ClinicalTrials.gov registry record · Phase 1
Use of [18F]FECNT in Positron Emission Tomography
A Phase 1 study, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
NCT00083629 is a Phase 1 study that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 30 participants.
The verdict
NCT00083629, a Phase 1 study, has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
Study Summary
This study will examine the use of a new radioactive tracer called \[18F\]FECNT in positron emission tomography (PET) scanning for measuring dopamine transporter (DAT) in the brain. DAT is found in brain neurons (nerve cells) that release the chemical messenger dopamine. By taking pictures of the DAT, scientists hope to learn more about the function of these neurons. Normal, healthy volunteers between 18 and 65 years of age may be eligible for this study. Candidates are screened with a medical history and physical examination, psychological assessment, and blood and urine tests. Subjects enrolled in the study participate in one of the following procedures: Brain Imaging Study: Part 1 Two catheters (small plastic tubes) are placed into veins in the subject's arms for injecting \[18F\]FECNT and for collecting blood samples during the scan. A third catheter is placed into a wrist artery to obtain arterial blood during the scan. With the catheters in place, the subject lies down on the scanner bed with his or her head placed in a special mask that limits movement during the brain scan. The scan begins with an initial x-ray like picture for about 10 minutes, after which the \[18F\]FECNT is injected and the actual PET scan starts. The entire procedure takes about 6 hours, including 2 hours of continuous scanning sessions, during which the subject is required to lie still. Subjects can relax out of the scanner between scans. They are monitored throughout the procedure. Vital signs are measured and electrocardiogram is taken once before and twice after injection of the tracer. At the end of the scanning, additional blood and urine samples are collected. Subjects are asked to urinate every 2 hours to lessen the radioactivity in the body. Whole Body Imaging Study: Part 2 For this procedure, a catheter is placed in a vein for injecting the \[18F\]FECNT tracer. A total of five scans are taken, each one spanning from head to upper thigh. During the course of the scans, x-r
Interventions
- PROCEDURE PET
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2004-05 |
| Est. Completion | 2005-09 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00083629
The ClinicalTrials.gov registry entry for NCT00083629 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which PET is the first listed.
NCT00083629 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00083629 about?
NCT00083629 is a clinical study titled "Use of [18F]FECNT in Positron Emission Tomography". This study will examine the use of a new radioactive tracer called \[18F\]FECNT in positron emission tomography (PET) scanning for measuring dopamine transporter (DAT) in the brain. DAT is found in brain neurons (nerve cells) that release the chemical messenger dopamine. By taking pictures of the DA...
What is the current status of trial NCT00083629?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2004-05. Estimated completion is 2005-09.
What interventions are being tested in trial NCT00083629?
The interventions under investigation include: PET (PROCEDURE).
Who is sponsoring clinical trial NCT00083629?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
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