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NCT00369915 · ClinicalTrials.gov registry record · Phase 2

The Antidepressant Efficacy of the Anticholinergic Scopolamine

A Phase 2 study, sponsored by National Institute of Mental Health (NIMH).

Terminated
Registry status
Phase 2
Development phase
17
Enrollment target

NCT00369915: Clinical Trial Phase 2 study, sponsored by National Institute of Mental Health (NIMH).

NCT00369915 is a Phase 2 study that was terminated before completion, run by National Institute of Mental Health (NIMH). The registered enrollment target is 17 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00369915, a Phase 2 study, was terminated before completion, sponsored by National Institute of Mental Health (NIMH).

TERMINATED
Registry status
Phase 2
Development phase
17 participants
Enrollment target

Study Summary

A previous study showed that the intravenous administration of scopolamine produces antidepressant effects. This study is designed to determine if other routes of administration of scopolamine produce antidepressant effects.

Primary Outcome

The Montgomery-Asberg Depression Rating Scale (MADRS) has a range of scores from 0 to 60 where the highest values indicate the most depression.

Interventions

  • DRUG Scopolamine

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2006-08
Est. Completion 2013-01
Phase Phase 2

Why NCT00369915 stopped before completion

NCT00369915 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% lower).

The record links to 0 conditions, and to 1 intervention - of which Scopolamine is the first listed.

NCT00369915 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00369915 about?

NCT00369915 is a clinical study titled "The Antidepressant Efficacy of the Anticholinergic Scopolamine". A previous study showed that the intravenous administration of scopolamine produces antidepressant effects. This study is designed to determine if other routes of administration of scopolamine produce antidepressant effects.

What is the current status of trial NCT00369915?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 17 participants. The study started on 2006-08. Estimated completion is 2013-01.

What interventions are being tested in trial NCT00369915?

The interventions under investigation include: Scopolamine (DRUG).

Who is sponsoring clinical trial NCT00369915?

This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00369915's enrollment target sits among peer trials

17 1903rd of 2000 higher than 93 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00369915, the US trial registry maintained by the National Library of Medicine. NCT00369915 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.