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NCT00069212 · ClinicalTrials.gov registry record
Psychobiological Mechanisms of Resilience to Trauma
A clinical trial, sponsored by National Institute of Mental Health (NIMH).
- Completed
- Registry status
- 210
- Enrollment target
NCT00069212 is a clinical trial that has completed, run by National Institute of Mental Health (NIMH). The registered enrollment target is 210 participants.
The verdict
NCT00069212 has completed, sponsored by National Institute of Mental Health (NIMH).
- COMPLETED
- Registry status
- 210 participants
- Enrollment target
Study Summary
This study will evaluate brain changes and psychological characteristics of people who are resilient to trauma. It will examine and compare responses in three categories of subjects: 1) people who have been exposed to a significant traumatic event and suffer symptoms of post-traumatic stress disorder (PTSD) severe enough to interfere with their ability to function; 2) people who have been exposed to a significant traumatic event and do not suffer PTSD symptoms severe enough to interfere with their ability to function; and 3) people who have never been exposed to a significant traumatic event. Most people who are exposed to trauma recover well from the adversity. Some may even benefit from it by, for example, gaining greater self-confidence of strengthening personal relationships. Others, however, develop PTSD and may have repeated thoughts, images, and dreams of the trauma; feel upset when reminded of the traumatic event; avoid places or people that remind them of the trauma; feel detached from others; have difficulty sleeping and concentrating; or startle easily. People in the three categories listed above may be eligible for this study. Candidates will be screened with a medical and psychiatric interview, evaluation of emotional intelligence (sensitivity to feelings of others), physical examination, electrocardiogram (EKG) and blood tests. Participants will undergo the following additional tests and procedures: * 24-hour urine collection and three urine drug screens over the course of the study. * Saliva collection every 2 hours on the day of the urine collection. * Magnetic resonance imaging (MRI) scans of the brain: Subjects will have three MRI scanning sessions to show brain structure and changes in blood flow in different regions of the brain that are responsible for emotion. MRI uses a strong magnetic field and radio waves to produce images of body tissues. During the scan, the subject lies on a table in a narrow cylinder containing a magnetic field and ma
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 210 participants |
| Start Date | 2003-09-16 |
| Est. Completion | 2012-09-17 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00069212
The ClinicalTrials.gov registry entry for NCT00069212 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 210 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Mental Health (NIMH), which has 343 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT00069212 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00069212 about?
NCT00069212 is a clinical study titled "Psychobiological Mechanisms of Resilience to Trauma". This study will evaluate brain changes and psychological characteristics of people who are resilient to trauma. It will examine and compare responses in three categories of subjects: 1) people who have been exposed to a significant traumatic event and suffer symptoms of post-traumatic stress disorde...
What is the current status of trial NCT00069212?
This trial is currently completed. The enrollment target is 210 participants. The study started on 2003-09-16. Estimated completion is 2012-09-17.
Who is sponsoring clinical trial NCT00069212?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
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