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ClinicalTrials.gov 147 recruiting now early-phase tilt #20 of 28,707 conditions

Ovarian Cancer: early-phase trial registry

147 of 338 indexed Ovarian Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #20 of 28,707 conditions by registered trial count.

338 US clinical trials · 147 currently recruiting · #20 of 28,707 conditions by registered trial count

Ovarian Cancer: 338 US clinical trials tracked, 147 recruiting.

Ovarian Cancer is the subject of 338 registered US clinical trials on ClinicalTrials.gov, 147 of them currently open to new participants. 28 are in Phase 3-4 (later-stage) and 230 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 31 of these trials.

Enrollment posture brief

Registry condition ovarian-cancer

OPEN 147 | RECR 43% | LATE 28 | EARLY 230 | RANK #20 | SPON 31

Nearest open-share peer: Cigarette Smoking (43% recruiting · 46 trials)

Ovarian Cancer (this)43%Type 2 Diabetes36.6%Lymphoma26.7%Diabetes25.1%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Ovarian Cancer

Ovarian Cancer lists 147 open slots (43% of 338 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ovarian Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ovarian Cancer is recruiting above its size-band peers.

    147 of 338 indexed trials (43.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Ovarian Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 31 of 338 trials (9.2%). 186 distinct sponsors appear on at least one study for this condition label.

  3. Typical Ovarian Cancer enrolment sits around 86 participants.

    Median target enrolment is 86 among the 323 trials that report a genuine target (sentinel values excluded). 172 of those (53.3%) plan for fewer than 100 participants.

  4. Ovarian Cancer research is mostly interventional.

    297 interventional and 41 observational studies make up this index (87.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1143Phase 287Phase 325Phase 43

Open and recent trials

338 total, page 4 of 7

ACTIVE NOT RECRUITING 1,315 participants

Estrogen, Diet, Genetics and Endometrial Cancer

Memorial Sloan Kettering Cancer Center

NCT00587886

ACTIVE NOT RECRUITING 1,047 participants

Evaluating an Alternative Clinical Genetics Cancer Care Delivery Model: A Pilot Study of Patient Outcomes

Memorial Sloan Kettering Cancer Center

NCT02917798

ACTIVE NOT RECRUITING 1,000 participants

Tempus Priority Study: A Pan-tumor Observational Study

Tempus AI

NCT05179824

ACTIVE NOT RECRUITING Phase 1 914 participants

Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Exelixis

NCT03170960

ACTIVE NOT RECRUITING Phase 1 840 participants

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

TScan Therapeutics

NCT05973487

ACTIVE NOT RECRUITING NA 797 participants

Trial on Radical Upfront Surgery in Advanced Ovarian Cancer

AGO Study Group

NCT02828618

ACTIVE NOT RECRUITING Phase 1 733 participants

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

OncoC4

NCT04140526

ACTIVE NOT RECRUITING Phase 1 702 participants

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

AstraZeneca

NCT04644068

ACTIVE NOT RECRUITING Phase 3 643 participants

Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65).

Merck Sharp & Dohme

NCT05116189

ACTIVE NOT RECRUITING Phase 3 615 participants

Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery

CanariaBio

NCT04498117

ACTIVE NOT RECRUITING Phase 2 534 participants

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

Hoffmann-La Roche

NCT02568267

ACTIVE NOT RECRUITING Phase 1 499 participants

Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer

Agenus

NCT03860272

ACTIVE NOT RECRUITING Phase 1 409 participants

Depression Treatment and Screening in Ovarian Cancer Patients

M.D. Anderson Cancer Center

NCT00515372

ACTIVE NOT RECRUITING NA 326 participants

Living WELL: A Web-Based Program for Ovarian Cancer Survivors

Susan Lutgendorf

NCT04533763

ACTIVE NOT RECRUITING Phase 1 288 participants

Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression

BicycleTx Limited

NCT04180371

ACTIVE NOT RECRUITING 240 participants

Biobehavioral and Sociodemographic Characteristics of Long Term Survivors of Ovarian Cancer

M.D. Anderson Cancer Center

NCT02043158

ACTIVE NOT RECRUITING Phase 2 225 participants

A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation

Verastem

NCT04625270

ACTIVE NOT RECRUITING Phase 3 220 participants

Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy

Memorial Sloan Kettering Cancer Center

NCT01223248

ACTIVE NOT RECRUITING Phase 3 185 participants

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

AstraZeneca

NCT04421963

ACTIVE NOT RECRUITING Phase 2 184 participants

Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumors

ImmunoVaccine Technologies, Inc. (IMV Inc.)

NCT03836352

ACTIVE NOT RECRUITING Phase 1 180 participants

P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors

Poseida Therapeutics

NCT05239143

ACTIVE NOT RECRUITING Phase 2 176 participants

A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

Hoffmann-La Roche

NCT04931342

ACTIVE NOT RECRUITING Phase 2 170 participants

A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies

Xencor

NCT05032040

ACTIVE NOT RECRUITING Phase 2 162 participants

Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer

AstraZeneca

NCT01081951

ACTIVE NOT RECRUITING Phase 2 154 participants

PF-07104091 as a Single Agent and in Combination Therapy

Pfizer

NCT04553133

ACTIVE NOT RECRUITING Phase 1 138 participants

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Toray Industries

NCT03872947

ACTIVE NOT RECRUITING Phase 1 120 participants

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

Uswm CT

NCT04044859

ACTIVE NOT RECRUITING Phase 1 110 participants

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Compugen

NCT04354246

ACTIVE NOT RECRUITING 100 participants

Diet, Hepcidin, and Chemotherapy RDI

George Washington University

NCT06483997

ACTIVE NOT RECRUITING Phase 1 97 participants

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants with Advanced Unresectable or Metastatic Solid Tumors

NextCure

NCT05572684

ACTIVE NOT RECRUITING Phase 2 92 participants

A Trial of Vigil for Participants With Ovarian Cancer

Gradalis

NCT02346747

ACTIVE NOT RECRUITING 78 participants

Assessing the Time Demands of Cancer

Masonic Cancer Center, University of Minnesota

NCT05708703

ACTIVE NOT RECRUITING Phase 2 75 participants

Juice Plus+ and Juice Plus+ Complete in Ovarian Cancer

M.D. Anderson Cancer Center

NCT01439659

ACTIVE NOT RECRUITING Phase 2 73 participants

A Phase II Study Of Nivolumab/ Bevacizumab/Rucaparib

Dana-Farber Cancer Institute

NCT02873962

ACTIVE NOT RECRUITING Phase 1 71 participants

MAGE-A4ᶜ¹º³²T for Multi-Tumor

Adaptimmune

NCT03132922

ACTIVE NOT RECRUITING Phase 3 68 participants

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Pfizer

NCT05059522

ACTIVE NOT RECRUITING Phase 2 66 participants

ADP-A2M4CD8 Monotherapy and in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Ovarian Cancer (SURPASS-3)

Uswm CT

NCT05601752

ACTIVE NOT RECRUITING Phase 2 63 participants

Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)

EMD Serono Research & Development Institute

NCT06433219

ACTIVE NOT RECRUITING 60 participants

Diagnostic Utility of Culdocentesis in Patients With a Suspicious Adnexal Mass

Southern Illinois University

NCT02109367

ACTIVE NOT RECRUITING Phase 2 58 participants

ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer

OncoC4

NCT05446298

ACTIVE NOT RECRUITING Phase 1 57 participants

Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer

TCR2 Therapeutics

NCT03907852

ACTIVE NOT RECRUITING Phase 1 50 participants

PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer

New Mexico Cancer Research Alliance

NCT02571725

ACTIVE NOT RECRUITING Phase 2 46 participants

BrUOG 354 Nivolumab +/- Ipilimumab for Ovarian and Extra-renal Clear Cell Carcinomas

Brown University

NCT03355976

ACTIVE NOT RECRUITING Phase 1 45 participants

A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer

Nuvectis Pharma

NCT05226507

ACTIVE NOT RECRUITING 43 participants

Assessment of Paclitaxel-Induced Neuropathy

University of Chicago

NCT01953159

ACTIVE NOT RECRUITING Phase 1 40 participants

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Arcus Biosciences

NCT05891171

ACTIVE NOT RECRUITING Phase 2 35 participants

Bevacizumab in Ovarian Cancer Patients With Disease at Second-Look Surgery

M.D. Anderson Cancer Center

NCT02884648

ACTIVE NOT RECRUITING NA 30 participants

Journey Ahead: Enhancing Coping and Communication for Women Diagnosed With Gynecological Cancer

Rutgers, The State University of New Jersey

NCT05220033

ACTIVE NOT RECRUITING 24 participants

Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian Cancer

Abramson Cancer Center at Penn Medicine

NCT06436248

ACTIVE NOT RECRUITING Phase 2 23 participants

Vaccination of Patients With Ovarian Cancer With Dendritic Cell/Tumor Fusions With Granulocyte Macrophage Colony-stimulating Factor (GM-CSF) and Imiquimod

Beth Israel Deaconess Medical Center

NCT00799110

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Phase Distribution

PhaseTrial count
Phase 1 143
Phase 2 87
Phase 3 25
Phase 4 3

Named interventions

Most-linked intervention names on Ovarian Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Bevacizumab Drug
19 trials
Paclitaxel Drug
18 trials
Carboplatin Drug
13 trials
paclitaxel Drug
12 trials
carboplatin Drug
10 trials
Cyclophosphamide Drug
10 trials
Fludarabine Drug
8 trials
Pembrolizumab Drug
8 trials

US sites by state

Facility locations filed on Ovarian Cancer trials. A trial with sites in several states counts in each.

New York 114 trials
California 105 trials
Texas 104 trials
Florida 86 trials
Massachusetts 74 trials
Pennsylvania 58 trials
Michigan 51 trials
Ohio 50 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ovarian Cancer page

338 registered trials, 147 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ovarian Cancer condition card totals 338 registered trials; most-linked intervention Bevacizumab; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.