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ClinicalTrials.gov 147 recruiting now official registry

Ovarian Cancer clinical trials

147 of 338 indexed Ovarian Cancer trials are currently recruiting.

338 US clinical trials · 147 currently recruiting

Ovarian Cancer is the subject of 338 registered US clinical trials on ClinicalTrials.gov, 147 of them currently open to new participants. 28 are in Phase 3-4 (later-stage) and 230 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 31 of these trials.

The research picture

Ovarian Cancer has 338 registered US clinical trials, 147 of them open to new participants right now, about 43% of the total.

147
recruiting participants now
43%
of trials open to enrollment
28
in Phase 3–4 (later-stage)
31
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 1143Phase 287Phase 325Phase 43

Active & Recent Trials

338 total, page 3 of 7

RECRUITING Phase 1 61 participants

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

Radiopharm Theranostics

NCT07189871

RECRUITING Phase 1 60 participants

Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies

National Cancer Institute (NCI)

NCT04847063

RECRUITING Phase 2 60 participants

Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer

Canadian Cancer Trials Group

NCT04918186

RECRUITING 60 participants

Clinical Pre-screening Protocol for Ovarian Cancer

Allarity Therapeutics

NCT03877796

RECRUITING Phase 1 60 participants

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

Compugen

NCT06888921

RECRUITING Phase 1 54 participants

Sacituzumab Govitecan in Combination With Cisplatin in Platinum Sensitive Recurrent Ovarian and Endometrial Cancer

Icahn School of Medicine at Mount Sinai

NCT06040970

RECRUITING Phase 2 51 participants

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

University of California, Irvine

NCT06580002

RECRUITING Phase 1 51 participants

Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer

M.D. Anderson Cancer Center

NCT05922930

RECRUITING NA 50 participants

Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation

University of Colorado, Denver

NCT06518746

RECRUITING 50 participants

Healthy Volunteers Study

Abramson Cancer Center at Penn Medicine

NCT06962059

RECRUITING Phase 1 48 participants

Clinical Trial of Autologous B7-H3 CAR T Cells in Reoccurent Platinum-resistant Ovarian Tumors

Stanford University

NCT06646627

RECRUITING Phase 1 46 participants

A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

AstraZeneca

NCT05877599

RECRUITING Phase 1 42 participants

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

Verismo Therapeutics

NCT05568680

RECRUITING Phase 2 40 participants

Decitabine and Selinexor in Combination to Reverse Drug Resistance With Standard Chemotherapy in Ovarian Cancer

Loyola University

NCT05983276

RECRUITING NA 40 participants

Comprehensive Yoga Therapy Based Lifestyle Prehabilitation Program for Women With Ovarian Cancer

M.D. Anderson Cancer Center

NCT06545604

RECRUITING Phase 1 40 participants

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

M.D. Anderson Cancer Center

NCT04038619

RECRUITING Phase 1 38 participants

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

Hefei TG ImmunoPharma Co.

NCT05746897

RECRUITING Phase 2 38 participants

Autophagy Maintenance (AUTOMAIN)

Medical University of South Carolina

NCT06971744

RECRUITING 35 participants

The Better, Harder, Faster, Stronger Study

Wake Forest University Health Sciences

NCT07220512

RECRUITING NA 35 participants

A Study Comparing Perioperative Stress Reduction vs. Standard of Care in Ovarian Cancer (PRESERVE)

Memorial Sloan Kettering Cancer Center

NCT05429970

RECRUITING Phase 1 34 participants

Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer

M.D. Anderson Cancer Center

NCT05636111

RECRUITING Phase 2 33 participants

ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer

Alexander B Olawaiye, MD

NCT05071937

RECRUITING Phase 2 33 participants

Telmisartan in Combination With Cytotoxic Regimens in Platinum-Resistant Ovarian Cancer

Tyler J Curiel

NCT06815497

RECRUITING Phase 1 33 participants

Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Masonic Cancer Center, University of Minnesota

NCT06342986

RECRUITING Phase 2 32 participants

Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin

Dana-Farber Cancer Institute

NCT06677190

RECRUITING Phase 2 31 participants

Regorafenib Combined With Fulvestrant in Recurrent Low-Grade Serous Ovarian Cancer

Sarah K. Lynam MD

NCT05113368

RECRUITING Phase 2 30 participants

Secondary Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Recurrent Mucinous Ovarian Cancer (HI-MOC Study)

M.D. Anderson Cancer Center

NCT05123807

RECRUITING Phase 1 30 participants

Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Imunon

NCT05739981

RECRUITING Phase 1 30 participants

DT2216 + Paclitaxel in Platinum-Resistant Ovarian Cancer

Elizabeth Stover, MD, PhD

NCT06964009

RECRUITING NA 30 participants

Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy

Dana-Farber Cancer Institute

NCT04997096

RECRUITING Phase 1 30 participants

A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer

Outpace Bio

NCT07030907

RECRUITING Phase 1 27 participants

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

Tanabe Pharma America

NCT06943521

RECRUITING Phase 1 27 participants

Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells

UNC Lineberger Comprehensive Cancer Center

NCT06305299

RECRUITING 25 participants

Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

Carevive Systems

NCT05974150

RECRUITING Phase 2 24 participants

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

University of California, Irvine

NCT07447050

RECRUITING Phase 1 24 participants

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

Nerviano Medical Sciences

NCT06930755

RECRUITING Phase 1 22 participants

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

Case Comprehensive Cancer Center

NCT06412510

RECRUITING Phase 2 20 participants

Newly Diagnosed Stage III/IV Ovarian Cancer, Neoadjuvant Carbo/Taxol/Pembro, Maintenance Olaparib/Pembro

University of Alabama at Birmingham

NCT05952453

RECRUITING Phase 1 20 participants

Microdevice In Ovarian, Fallopian Tube, And Peritoneal Cancer

Brigham and Women's Hospital

NCT04701645

RECRUITING Phase 2 20 participants

Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy

M.D. Anderson Cancer Center

NCT06083844

RECRUITING Phase 1 20 participants

Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence

University of Colorado, Denver

NCT06430541

RECRUITING 18 participants

Cognitive Impact of Neoadjuvant Chemotherapy for Ovarian Cancer

University of Wisconsin, Madison

NCT07125209

RECRUITING Phase 1 18 participants

Trial of THEO-260 (Administered Via Intraperitoneal Route) in Ovarian Cancer Patients

Theolytics Limited

NCT07211659

RECRUITING Phase 1 18 participants

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

Dana-Farber Cancer Institute

NCT06321484

RECRUITING Phase 1 10 participants

Infusion of Autologous T Cells Engineered to Target FSH Receptor in Recurrent Ovarian Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT05316129

RECRUITING Phase 1 9 participants

Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors

Radiopharm Theranostics

NCT05799274

RECRUITING Phase 1 8 participants

Safety and Immunogenicity of Innocell Autologous Cellular Immunotherapy for Recurrent Epithelial Ovarian Cancer

PhotonPharma

NCT06366490

ACTIVE NOT RECRUITING NA 21,081 participants

Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT00579514

ACTIVE NOT RECRUITING 13,320 participants

Clinical Significance of Germline BRCA Mutations

Memorial Sloan Kettering Cancer Center

NCT00579488

ACTIVE NOT RECRUITING Phase 3 1,367 participants

Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

Merck Sharp & Dohme

NCT03740165

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Phase Distribution

PhaseTrial count
Phase 1 143
Phase 2 87
Phase 3 25
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Ovarian Cancer Trial Landscape

338 indexed Ovarian Cancer studies · 147 recruiting (43%).

Phase mix: 28 late (III/IV) vs 230 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (31 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Ovarian Cancer?

PlainTrial tracks 338 US clinical trials for Ovarian Cancer, of which 147 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Ovarian Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.