Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery
NCT04498117 · View on ClinicalTrials.gov ↗
Study Summary
Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemotherapy regimen (paclitaxel and carboplatin), for the treatment of subjects with newly diagnosed advanced ovarian cancer who have undergone optimal debulking.
Conditions Studied
Interventions
- DRUG Carboplatin
- DRUG Paclitaxel
- BIOLOGICAL Placebo
- BIOLOGICAL Oregovomab
Study Locations (20)
California
- John Muir Health Clinical Research Center — Concord
- Kaiser Permanente Southern California — Irvine
- Moores UC San Diego Cancer Center — La Jolla
- Kaiser Permanente Los Angeles Medical Center — Los Angeles
- Epic Care — Pleasant Hill
- Kaiser Permanente Riverside Medical Center — Riverside
- University of California, Davis Comprehensive Cancer Center — Sacramento
- Contra Costa Oncology — Walnut Creek
- John Muir Health Gynecologic Cancer Services — Walnut Creek
Connecticut
- University of Connecticut Health Center — Farmington
- Smilow Cancer Hospital — New Haven
- Yale University School of Medicine — New Haven
Arizona
- Honor Health — Phoenix
- The University of Arizona Cancer Center — Tucson
Florida
- AdventHealth Orlando — Orlando
- Women's Cancer Florida/Women's Cancer Associates — St. Petersburg
Hawaii
- The Queens Medical Center — Honolulu
- Kapiolani Medical Center for Women and Children/University of Hawaii — Honolulu
Colorado
- University of Colorado Health — Aurora
Georgia
- Lewis Cancer & Research Pavilion at St. Joseph's Candler — Savannah
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 615 participants |
| Start Date | 2020-08-25 |
| Est. Completion | 2028-08-26 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04498117
The ClinicalTrials.gov registry entry for NCT04498117 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 615 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is CanariaBio, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 4 interventions — of which Carboplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04498117 reports 20 study locations spanning 7 distinct geographic areas — top geographies include California, Connecticut, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04498117 about?
NCT04498117 is a clinical study titled "Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery". Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemotherapy regimen (paclitaxel and carboplatin), for the treatment of subjects with newly diagnosed advanced ovarian cancer who have undergone optimal deb...
What is the current status of trial NCT04498117?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 615 participants. The study started on 2020-08-25. Estimated completion is 2028-08-26.
What conditions does trial NCT04498117 study?
This clinical trial studies the following conditions: Ovarian Cancer, Ovarian Neoplasms, Peritoneal Cancer, Peritoneal Neoplasms, Fallopian Tube Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04498117?
The interventions under investigation include: Carboplatin (DRUG), Paclitaxel (DRUG), Placebo (BIOLOGICAL), Oregovomab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04498117?
This trial is sponsored by CanariaBio, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04498117 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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