Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Lymphoma

Open-data reference.

330 US clinical trials · 88 currently recruiting

Active & Recent Trials

RECRUITING 15,000 participants

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

UNC Lineberger Comprehensive Cancer Center

NCT01137643

RECRUITING 3,000 participants

Sample Collection and Tracking for the Developmental Therapeutics Clinic

National Cancer Institute (NCI)

NCT03269578

RECRUITING 3,000 participants

Registry of Older Patients With Cancer

UNC Lineberger Comprehensive Cancer Center

NCT01137825

RECRUITING 2,000 participants

Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis

University of Alabama at Birmingham

NCT05898477

RECRUITING 1,100 participants

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

National Cancer Institute (NCI)

NCT01441089

RECRUITING NA 700 participants

HEME Home Transfusion Program

Dana-Farber Cancer Institute

NCT06487247

RECRUITING Phase 3 668 participants

Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

University of Rochester

NCT05006482

RECRUITING NA 517 participants

Feasibility and Clinical Utility of Cell-free DNA (cfDNA) in Identifying Actionable Alterations and Minimal Residual Disease for Lymphoma Patients Across Community Centers in Texas

M.D. Anderson Cancer Center

NCT05676450

RECRUITING 500 participants

Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders

Memorial Sloan Kettering Cancer Center

NCT00582621

RECRUITING Phase 4 500 participants

Vaccine Responses in Patients With B Cell Malignancies

National Heart, Lung, and Blood Institute (NHLBI)

NCT05170399

RECRUITING NA 500 participants

DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics

UNC Lineberger Comprehensive Cancer Center

NCT06296368

RECRUITING 475 participants

Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma

Memorial Sloan Kettering Cancer Center

NCT01788839

RECRUITING NA 400 participants

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

University of Miami

NCT05745285

RECRUITING Phase 1 370 participants

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Merck Sharp & Dohme

NCT02332668

RECRUITING Phase 2 358 participants

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

Center for International Blood and Marrow Transplant Research

NCT06859424

RECRUITING NA 356 participants

Mosaic Trial for Stem Cell Transplant Recipients

Northwestern University

NCT06960993

RECRUITING Phase 2 300 participants

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

Masonic Cancer Center, University of Minnesota

NCT03314974

RECRUITING NA 260 participants

Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors

Duke University

NCT06371768

RECRUITING NA 250 participants

WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)

Mayo Clinic

NCT07058064

RECRUITING NA 210 participants

xDRIVE for Florida-based Cancer Patients

First Ascent Biomedical

NCT07167381

RECRUITING 200 participants

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

AIDS Malignancy Consortium

NCT05663502

RECRUITING Phase 3 182 participants

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

Hoffmann-La Roche

NCT06084936

RECRUITING Phase 1 180 participants

TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas

Treeline Biosciences

NCT07082803

RECRUITING Phase 1 155 participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

National Cancer Institute (NCI)

NCT03223610

RECRUITING 154 participants

Study of CAR-T Therapy in Older Patients

Memorial Sloan Kettering Cancer Center

NCT04300998

RECRUITING Phase 2 152 participants

A Study of Mosunetuzumab Alone or With Zanubrutinib in People With Follicular Lymphoma

Memorial Sloan Kettering Cancer Center

NCT05389293

RECRUITING Phase 1 136 participants

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

Baylor College of Medicine

NCT01555892

RECRUITING Phase 2 134 participants

A Study of Mogamulizumab to Prevent Adult T-cell Leukemia/Lymphoma in People With HTLV-1

Memorial Sloan Kettering Cancer Center

NCT06698003

RECRUITING Phase 1 110 participants

AZD3470 as Monotherapy and in Combination With Anticancer Agents in Participants With Relapsed/Refractory Haematologic Malignancies.

AstraZeneca

NCT06137144

RECRUITING Early Phase 1 104 participants

Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy

University of Oklahoma

NCT05921253

RECRUITING Phase 1 104 participants

CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

University of Chicago

NCT07294677

RECRUITING Early Phase 1 100 participants

Exercise as an Immune Adjuvant for Allogeneic Cell Therapies

University of Arizona

NCT06643221

RECRUITING NA 100 participants

Living Well With Lymphoma

University of Michigan Rogel Cancer Center

NCT06047626

RECRUITING 100 participants

Pediatric PET/MR Image Registry

Stanford University

NCT03458520

RECRUITING 100 participants

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

M.D. Anderson Cancer Center

NCT05011045

RECRUITING NA 90 participants

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

Massachusetts General Hospital

NCT05646576

RECRUITING 88 participants

Natural History Study to Determine Drug Metabolism Phenotype and Appropriate Germline Source DNA in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant

National Cancer Institute (NCI)

NCT06856226

RECRUITING NA 88 participants

Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant

University of Nebraska

NCT04898790

RECRUITING Phase 2 83 participants

Study of Ruxolitinib in Relapsed or Refractory T or NK Cell Lymphoma

Memorial Sloan Kettering Cancer Center

NCT02974647

RECRUITING Phase 1 75 participants

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

Turning Point Therapeutics

NCT04094610

RECRUITING NA 74 participants

UPLYFT For Lymphoma Survivors

Dana-Farber Cancer Institute

NCT05080166

RECRUITING Phase 1 72 participants

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

Caribou Biosciences

NCT04637763

RECRUITING Phase 2 65 participants

A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

NCT07015242

RECRUITING Phase 1 60 participants

A Phase 1/2, Open-label Study of Valemetostat in Combination With Rituximab and Lenalidomide in Relapsed or Refractory Follicular Lymphoma

M.D. Anderson Cancer Center

NCT05683171

RECRUITING NA 60 participants

A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties

Memorial Sloan Kettering Cancer Center

NCT07052916

RECRUITING Early Phase 1 60 participants

Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma

Mayo Clinic

NCT05294367

RECRUITING 60 participants

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

National Cancer Institute (NCI)

NCT05237986

RECRUITING Phase 2 60 participants

BRAZAN: A Randomized Phase 2 Study of Bendamustine, Rituximab, Cytarabine (AraC) Induction With Zanubrutinib (BRAZAN) Followed by Zanubrutinib/Rituximab +/- Sonrotoclax Maintenance in Treatment-Naïve Mantle Cell Lymphoma

Christine Ryan

NCT06854003

RECRUITING Phase 3 60 participants

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

St. Louis University

NCT03823534

RECRUITING Phase 1 55 participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma

National Cancer Institute (NCI)

NCT04739813

RECRUITING Phase 1 50 participants

A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma

Treeline Biosciences

NCT06733441

RECRUITING Phase 2 50 participants

A Study of Response Adapted Ultra Low Dose 4 Gy Radiation for Definitive Therapy of Marginal Zone Lymphoma

M.D. Anderson Cancer Center

NCT05929612

RECRUITING Phase 1 50 participants

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Hoffmann-La Roche

NCT06624085

RECRUITING Phase 2 49 participants

A Study of Carmustine With and Without Ethanol in Subjects With Lymphoma

VIVUS

NCT06915246

RECRUITING NA 48 participants

Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers

Memorial Sloan Kettering Cancer Center

NCT05940272

RECRUITING Phase 2 45 participants

Epco, Zanu, Ritux for R/R FL or MZL

Reid Merryman, MD

NCT06563596

RECRUITING Phase 1 42 participants

A Phase I Safety and Pharmacokinetic Study of Gamitrinib Administered Intravenously to Patients With Advanced Cancer

Fox Chase Cancer Center

NCT04827810

RECRUITING Phase 2 41 participants

A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma

Jennifer Crombie, MD

NCT05800366

RECRUITING NA 40 participants

An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers

Washington University School of Medicine

NCT07226934

RECRUITING NA 40 participants

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

UNC Lineberger Comprehensive Cancer Center

NCT06860880

RECRUITING Phase 2 40 participants

Pilot Trial of Fecal Microbiota Transplantation for Lymphoma Patients Receiving Axicabtagene Ciloleucel Therapy.

M.D. Anderson Cancer Center

NCT06218602

RECRUITING Phase 2 40 participants

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

National Cancer Institute (NCI)

NCT03258567

RECRUITING Phase 2 40 participants

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

Spectrum Pharmaceuticals

NCT04570423

RECRUITING Phase 1 40 participants

Mosunetuzumab for CLL MRD Clearance

Inhye Ahn

NCT07052695

RECRUITING 40 participants

Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors

M.D. Anderson Cancer Center

NCT01608152

RECRUITING NA 40 participants

ctDNA-guided Therapy Optimization in Newly Diagnosed DLBCL

Hua-Jay J Cherng, MD

NCT06693830

RECRUITING NA 40 participants

Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy

University of Utah

NCT07390071

RECRUITING Phase 2 40 participants

Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell Lymphoma

M.D. Anderson Cancer Center

NCT02106988

RECRUITING Phase 2 39 participants

Isatuximab During Stem Cell Collection and Transplant in Patients With Multiple Myeloma and Lymphoma

Divaya Bhutani

NCT05346809

RECRUITING Phase 2 36 participants

A Phase 2 Trial of Mosunetuzumab and Zanubrutinib for Patients With Relapsed/Refractory Marginal Zone Lymphoma

M.D. Anderson Cancer Center

NCT06563505

RECRUITING Phase 2 35 participants

Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy

Beth Israel Deaconess Medical Center

NCT06510361

RECRUITING Phase 2 35 participants

Odronextamab in Low Tumor Volume Advanced FL

Gottfried von Keudell, MD PhD

NCT07128641

RECRUITING Phase 2 33 participants

Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma

Gottfried von Keudell, MD PhD

NCT06510309

RECRUITING Phase 2 30 participants

A Phase II Study of Loncastuximab Tesirine as Consolidation Strategy in Patients With LBCL in PR After CAR T-cell Therapy

M.D. Anderson Cancer Center

NCT05464719

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

RECRUITING NA 30 participants

Study Using Prebiotics to Improve Gut Microbiome Diversity After Autologous Stem Cell Transplantation

University of Nebraska

NCT05135351

RECRUITING Phase 2 30 participants

Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)

Jennifer Amengual

NCT06954805

RECRUITING 30 participants

Umbilical Cord Blood Transplantation From Unrelated Donors

University of Rochester

NCT03016806

RECRUITING Phase 2 27 participants

A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma

Memorial Sloan Kettering Cancer Center

NCT07030699

RECRUITING NA 24 participants

Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial

Dana-Farber Cancer Institute

NCT06923397

RECRUITING Phase 1 21 participants

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

Estrella Biopharma

NCT06343311

RECRUITING Phase 2 20 participants

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Leland Metheny

NCT06680661

RECRUITING Phase 1 20 participants

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

ITM Solucin

NCT06441331

RECRUITING Phase 1 18 participants

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

St. Jude Children's Research Hospital

NCT06326463

RECRUITING Phase 1 15 participants

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

Dana-Farber Cancer Institute

NCT06475235

RECRUITING Phase 1 10 participants

Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)

City of Hope Medical Center

NCT05371132

RECRUITING Early Phase 1 8 participants

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06398457

RECRUITING

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Barbara Ann Karmanos Cancer Institute

NCT00935090

ACTIVE NOT RECRUITING 89,655 participants

Agriculture Health Study

National Cancer Institute (NCI)

NCT00352924

ACTIVE NOT RECRUITING Phase 2 373 participants

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

Eastern Cooperative Oncology Group

NCT01415752

ACTIVE NOT RECRUITING Phase 1 320 participants

A Study of GRC 54276 in Participants With Advanced Solid Tumors and Lymphomas.

Glenmark Specialty S.A.

NCT05878691

ACTIVE NOT RECRUITING Phase 2 313 participants

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

Center for International Blood and Marrow Transplant Research

NCT06001385

ACTIVE NOT RECRUITING NA 300 participants

Supportive Oncology Care At Home RCT

Massachusetts General Hospital

NCT04544046

ACTIVE NOT RECRUITING Phase 2 300 participants

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Center for International Blood and Marrow Transplant Research

NCT04904588

ACTIVE NOT RECRUITING NA 261 participants

Survivorship Care Plans and Telehealth Education for the Improvement of Access to Cancer Survivorship, the IMPACT Study

Fred Hutchinson Cancer Center

NCT04081779

ACTIVE NOT RECRUITING Phase 1 253 participants

Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas

Taiho Oncology

NCT02503423

ACTIVE NOT RECRUITING NA 180 participants

Comparison of Imaging Characteristics of uEXPLORER and Conventional PET/CT in Patients With Lung Cancer, Lymphoma, and Melanoma

University of California, Davis

NCT04478318

ACTIVE NOT RECRUITING Phase 3 173 participants

Lactobacillus Plantarum in Preventing Acute Graft Versus Host Disease in Children Undergoing Donor Stem Cell Transplant

Children's Oncology Group

NCT03057054

ACTIVE NOT RECRUITING Phase 2 140 participants

Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies

Children's Hospital of Philadelphia

NCT02323867

ACTIVE NOT RECRUITING NA 130 participants

Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer

M.D. Anderson Cancer Center

NCT03141437

Phase Distribution

PhaseTrial count
Early Phase 1 119
Phase 2 110
Phase 3 22
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Lymphoma Trial Landscape

ClinicalTrials.gov lists 330 US studies indexed under Lymphoma, and 88 of those are currently open to recruitment — roughly 27% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Lymphoma shows 25 late-stage studies (Phase 3 and Phase 4 combined) alongside 229 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Lymphoma is led by Memorial Sloan Kettering Cancer Center with 34 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lymphoma?

PlainTrial tracks 330 US clinical trials for Lymphoma, of which 88 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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