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ClinicalTrials.gov 147 recruiting now official registry

Ovarian Cancer clinical trials

147 of 338 indexed Ovarian Cancer trials are currently recruiting.

338 US clinical trials · 147 currently recruiting

Ovarian Cancer is the subject of 338 registered US clinical trials on ClinicalTrials.gov, 147 of them currently open to new participants. 28 are in Phase 3-4 (later-stage) and 230 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 31 of these trials.

The research picture

Ovarian Cancer has 338 registered US clinical trials, 147 of them open to new participants right now, about 43% of the total.

147
recruiting participants now
43%
of trials open to enrollment
28
in Phase 3–4 (later-stage)
31
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 1143Phase 287Phase 325Phase 43

Active & Recent Trials

338 total, page 5 of 7

ACTIVE NOT RECRUITING Phase 1 22 participants

NeoVax With Nivolumab in Patients With Ovarian Cancer

Dana-Farber Cancer Institute

NCT04024878

ACTIVE NOT RECRUITING NA 22 participants

Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy

Memorial Sloan Kettering Cancer Center

NCT04204811

ACTIVE NOT RECRUITING NA 21 participants

Genetic Testing in African Americans

Augusta University

NCT05591131

ACTIVE NOT RECRUITING Phase 2 20 participants

EON: A Single-arm Phase II Study of Etigilimab (OMP-313M32) in Combination With Checkpoint Inhibition (Nivolumab) in Patients With Platinum-resistant, Recurrent Epithelial Ovarian Cancer

M.D. Anderson Cancer Center

NCT05715216

ACTIVE NOT RECRUITING NA 20 participants

Nudge to Gynecologic Oncology

Abramson Cancer Center at Penn Medicine

NCT06451263

ACTIVE NOT RECRUITING Phase 2 19 participants

Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer

National Cancer Institute (NCI)

NCT05185947

ACTIVE NOT RECRUITING Phase 1 18 participants

Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer

Virginia Commonwealth University

NCT04502602

ACTIVE NOT RECRUITING Phase 2 16 participants

Safety and Efficacy of Anti-CD47, ALX148 in Combination With Liposomal Doxorubicin and Pembrolizumab in Recurrent Platinum-resistant Ovarian Cancer

Alexander B Olawaiye, MD

NCT05467670

ACTIVE NOT RECRUITING NA 10 participants

Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer

Memorial Sloan Kettering Cancer Center

NCT04454450

ACTIVE NOT RECRUITING Phase 2 10 participants

A Study of Second Look Laparoscopy (SLL) in People With Ovarian Cancer Who Have Completed Their First Course of Chemotherapy

Memorial Sloan Kettering Cancer Center

NCT06240598

ACTIVE NOT RECRUITING Phase 1 6 participants

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

TCR2 Therapeutics

NCT05451849

COMPLETED 10,805 participants

Continuation of Follow-up of DES-Exposed Cohorts

National Cancer Institute (NCI)

NCT00340600

COMPLETED 1,452 participants

Cancer Screening and Prevention Program for High Risk Women

NYU Langone Health

NCT00849199

COMPLETED 1,429 participants

PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine

Labcorp Corporation of America Holdings

NCT05697198

COMPLETED Phase 3 1,301 participants

A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Hoffmann-La Roche

NCT03038100

COMPLETED Phase 3 940 participants

Efficacy and Safety of Pazopanib Monotherapy After First Line Chemotherapy in Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Novartis Pharmaceuticals

NCT00866697

COMPLETED Phase 3 571 participants

Carboplatin Plus Paclitaxel With or Without Continued Low-Dose Paclitaxel in Treating Patients With Early-Stage Ovarian Cancer

Gynecologic Oncology Group

NCT00003644

COMPLETED 566 participants

Risk of Ovarian Cancer in Patients With a Pelvic Mass

Fujirebio Diagnostics

NCT00315692

COMPLETED Phase 3 566 participants

A Study Of Avelumab Alone Or In Combination With Pegylated Liposomal Doxorubicin Versus Pegylated Liposomal Doxorubicin Alone In Patients With Platinum Resistant/Refractory Ovarian Cancer (JAVELIN Ovarian 200)

Pfizer

NCT02580058

COMPLETED Phase 3 540 participants

Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)

NovoCure

NCT03940196

COMPLETED Phase 2 491 participants

A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)

pharmaand

NCT01891344

COMPLETED 478 participants

The Effect of TRA-8 on Ovarian Cancer Tissue

University of Alabama at Birmingham

NCT00711932

COMPLETED Phase 2 463 participants

A Study of Niraparib in Patients With Ovarian Cancer Who Have Received Three or Four Previous Chemotherapy Regimens

Tesaro

NCT02354586

COMPLETED Phase 3 324 participants

Paclitaxel and Cisplatin in Treating Patients With Stage III or Stage IV Ovarian Cancer or Primary Peritoneal Cancer

Gynecologic Oncology Group

NCT00002717

COMPLETED Phase 1 313 participants

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers

Five Prime Therapeutics

NCT02526017

COMPLETED NA 301 participants

OPTimizing Treatment Focused Genetic Testing IN Cancer

Dana-Farber Cancer Institute

NCT04066361

COMPLETED NA 276 participants

Decision Support for BRCA Testing in Ethnically Diverse Women

Columbia University

NCT03470402

COMPLETED Phase 1 229 participants

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

Esperas Pharma

NCT02632448

COMPLETED Phase 1 215 participants

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

NeoImmuneTech

NCT04332653

COMPLETED NA 204 participants

Stress, Immunity and Cervical Cancer: Biobehavioral Outcomes

University of California, Irvine

NCT00496106

COMPLETED Phase 3 198 participants

A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families

Tufts Medical Center

NCT00782145

COMPLETED Phase 1 184 participants

Phase 1b/2 Study of Carfilzomib in Relapsed Solid Tumors, Multiple Myeloma, or Lymphoma

Amgen

NCT00531284

COMPLETED 176 participants

Lynne Cohen Consortium Project: Multi-Center Database/Registry

M.D. Anderson Cancer Center

NCT00776958

COMPLETED Phase 2 172 participants

A Study of Prexasertib (LY2606368) in Platinum-Resistant or Refractory Recurrent Ovarian Cancer

Eli Lilly and Company

NCT03414047

COMPLETED NA 171 participants

Acupressure for Fatigue in Ovarian Cancer Survivors

University of Michigan Rogel Cancer Center

NCT03763838

COMPLETED Phase 3 170 participants

Methods in Education for Breast Cancer Genetics

National Cancer Institute (NCI)

NCT00001806

COMPLETED 169 participants

How Our Immune System Can Help Fight Cancer

Winthrop University Hospital

NCT01042847

COMPLETED Phase 1 152 participants

A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)

Astellas Pharma

NCT00889382

COMPLETED Phase 1 149 participants

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

Incyte Corporation

NCT03314935

COMPLETED Phase 2 148 participants

A Randomized Study of Safety and Efficacy of Pazopanib and Gemcitabine in Persistent or Relapsed Ovarian Cancer

Linda R Duska

NCT01610206

COMPLETED Phase 2 146 participants

Standard Infusion Carboplatin Versus Prophylactic Extended Infusion Carboplatin in Patients With Patients With Recurrent, Ovary, Fallopian Tube, and Primary Peritoneal Cancer

Memorial Sloan Kettering Cancer Center

NCT01248962

COMPLETED Phase 2 132 participants

TEACO: Taxotere, Eloxatin, Avastin in Cancer of the Ovary

Sanofi

NCT00296816

COMPLETED Phase 2 127 participants

Effect of Flutamide on Biomarkers in Blood and Tissue Samples From Patients at High Risk of Ovarian Cancer

University of Arizona

NCT00699907

COMPLETED 125 participants

Feasibility of Multi-gene Panel Testing at the Time of Diagnosis for Patients With Ovarian Cancer

NYU Langone Health

NCT03656809

COMPLETED Phase 2 124 participants

Phase II ABT-888 With Cyclophosphamide

National Cancer Institute (NCI)

NCT01306032

COMPLETED 121 participants

Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers

Memorial Sloan Kettering Cancer Center

NCT00608452

COMPLETED Phase 1 107 participants

Safety of BKM120 Monotherapy in Advanced Solid Tumor Patients

Novartis Pharmaceuticals

NCT01068483

COMPLETED Phase 1 103 participants

AMG386 Comb w. Either Pegylated Liposomal Doxorubicin or Topotecan Subjects w. Advanced Recurrent Epithelial Ovarian CR

Amgen

NCT00770536

COMPLETED Phase 2 82 participants

Gemcitabine, Docetaxel, and Filgrastim in Treating Patients With Recurrent or Persistent Leiomyosarcoma or Soft Tissue Sarcoma

Memorial Sloan Kettering Cancer Center

NCT00004066

COMPLETED Phase 2 80 participants

Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer

University of California, San Francisco

NCT00003072

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Phase Distribution

PhaseTrial count
Phase 1 143
Phase 2 87
Phase 3 25
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Ovarian Cancer Trial Landscape

338 indexed Ovarian Cancer studies · 147 recruiting (43%).

Phase mix: 28 late (III/IV) vs 230 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (31 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Ovarian Cancer?

PlainTrial tracks 338 US clinical trials for Ovarian Cancer, of which 147 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Ovarian Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.