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ClinicalTrials.gov 147 recruiting now early-phase tilt #20 of 28,707 conditions

Ovarian Cancer: early-phase trial registry

147 of 338 indexed Ovarian Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #20 of 28,707 conditions by registered trial count.

338 US clinical trials · 147 currently recruiting · #20 of 28,707 conditions by registered trial count

Ovarian Cancer: 338 US clinical trials tracked, 147 recruiting.

Ovarian Cancer is the subject of 338 registered US clinical trials on ClinicalTrials.gov, 147 of them currently open to new participants. 28 are in Phase 3-4 (later-stage) and 230 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 31 of these trials.

Enrollment posture brief

Registry condition ovarian-cancer

OPEN 147 | RECR 43% | LATE 28 | EARLY 230 | RANK #20 | SPON 31

Nearest open-share peer: Cigarette Smoking (43% recruiting · 46 trials)

Ovarian Cancer (this)43%Type 2 Diabetes36.6%Lymphoma26.7%Diabetes25.1%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Ovarian Cancer

Ovarian Cancer lists 147 open slots (43% of 338 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Ovarian Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Ovarian Cancer is recruiting above its size-band peers.

    147 of 338 indexed trials (43.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Ovarian Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 31 of 338 trials (9.2%). 186 distinct sponsors appear on at least one study for this condition label.

  3. Typical Ovarian Cancer enrolment sits around 86 participants.

    Median target enrolment is 86 among the 323 trials that report a genuine target (sentinel values excluded). 172 of those (53.3%) plan for fewer than 100 participants.

  4. Ovarian Cancer research is mostly interventional.

    297 interventional and 41 observational studies make up this index (87.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1143Phase 287Phase 325Phase 43

Open and recent trials

338 total, page 5 of 7

ACTIVE NOT RECRUITING Phase 1 22 participants

NeoVax With Nivolumab in Patients With Ovarian Cancer

Dana-Farber Cancer Institute

NCT04024878

ACTIVE NOT RECRUITING NA 22 participants

Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy

Memorial Sloan Kettering Cancer Center

NCT04204811

ACTIVE NOT RECRUITING NA 21 participants

Genetic Testing in African Americans

Augusta University

NCT05591131

ACTIVE NOT RECRUITING Phase 2 20 participants

EON: A Single-arm Phase II Study of Etigilimab (OMP-313M32) in Combination With Checkpoint Inhibition (Nivolumab) in Patients With Platinum-resistant, Recurrent Epithelial Ovarian Cancer

M.D. Anderson Cancer Center

NCT05715216

ACTIVE NOT RECRUITING NA 20 participants

Nudge to Gynecologic Oncology

Abramson Cancer Center at Penn Medicine

NCT06451263

ACTIVE NOT RECRUITING Phase 2 19 participants

Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer

National Cancer Institute (NCI)

NCT05185947

ACTIVE NOT RECRUITING Phase 1 18 participants

Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer

Virginia Commonwealth University

NCT04502602

ACTIVE NOT RECRUITING Phase 2 16 participants

Safety and Efficacy of Anti-CD47, ALX148 in Combination With Liposomal Doxorubicin and Pembrolizumab in Recurrent Platinum-resistant Ovarian Cancer

Alexander B Olawaiye, MD

NCT05467670

ACTIVE NOT RECRUITING NA 10 participants

Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer

Memorial Sloan Kettering Cancer Center

NCT04454450

ACTIVE NOT RECRUITING Phase 2 10 participants

A Study of Second Look Laparoscopy (SLL) in People With Ovarian Cancer Who Have Completed Their First Course of Chemotherapy

Memorial Sloan Kettering Cancer Center

NCT06240598

ACTIVE NOT RECRUITING Phase 1 6 participants

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

TCR2 Therapeutics

NCT05451849

COMPLETED 10,805 participants

Continuation of Follow-up of DES-Exposed Cohorts

National Cancer Institute (NCI)

NCT00340600

COMPLETED 1,452 participants

Cancer Screening and Prevention Program for High Risk Women

NYU Langone Health

NCT00849199

COMPLETED 1,429 participants

PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine

Labcorp Corporation of America Holdings

NCT05697198

COMPLETED Phase 3 1,301 participants

A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Hoffmann-La Roche

NCT03038100

COMPLETED Phase 3 940 participants

Efficacy and Safety of Pazopanib Monotherapy After First Line Chemotherapy in Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Novartis Pharmaceuticals

NCT00866697

COMPLETED Phase 3 571 participants

Carboplatin Plus Paclitaxel With or Without Continued Low-Dose Paclitaxel in Treating Patients With Early-Stage Ovarian Cancer

Gynecologic Oncology Group

NCT00003644

COMPLETED 566 participants

Risk of Ovarian Cancer in Patients With a Pelvic Mass

Fujirebio Diagnostics

NCT00315692

COMPLETED Phase 3 566 participants

A Study Of Avelumab Alone Or In Combination With Pegylated Liposomal Doxorubicin Versus Pegylated Liposomal Doxorubicin Alone In Patients With Platinum Resistant/Refractory Ovarian Cancer (JAVELIN Ovarian 200)

Pfizer

NCT02580058

COMPLETED Phase 3 540 participants

Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)

NovoCure

NCT03940196

COMPLETED Phase 2 491 participants

A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)

pharmaand

NCT01891344

COMPLETED 478 participants

The Effect of TRA-8 on Ovarian Cancer Tissue

University of Alabama at Birmingham

NCT00711932

COMPLETED Phase 2 463 participants

A Study of Niraparib in Patients With Ovarian Cancer Who Have Received Three or Four Previous Chemotherapy Regimens

Tesaro

NCT02354586

COMPLETED Phase 3 324 participants

Paclitaxel and Cisplatin in Treating Patients With Stage III or Stage IV Ovarian Cancer or Primary Peritoneal Cancer

Gynecologic Oncology Group

NCT00002717

COMPLETED Phase 1 313 participants

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers

Five Prime Therapeutics

NCT02526017

COMPLETED NA 301 participants

OPTimizing Treatment Focused Genetic Testing IN Cancer

Dana-Farber Cancer Institute

NCT04066361

COMPLETED NA 276 participants

Decision Support for BRCA Testing in Ethnically Diverse Women

Columbia University

NCT03470402

COMPLETED Phase 1 229 participants

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

Esperas Pharma

NCT02632448

COMPLETED Phase 1 215 participants

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

NeoImmuneTech

NCT04332653

COMPLETED NA 204 participants

Stress, Immunity and Cervical Cancer: Biobehavioral Outcomes

University of California, Irvine

NCT00496106

COMPLETED Phase 3 198 participants

A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families

Tufts Medical Center

NCT00782145

COMPLETED Phase 1 184 participants

Phase 1b/2 Study of Carfilzomib in Relapsed Solid Tumors, Multiple Myeloma, or Lymphoma

Amgen

NCT00531284

COMPLETED 176 participants

Lynne Cohen Consortium Project: Multi-Center Database/Registry

M.D. Anderson Cancer Center

NCT00776958

COMPLETED Phase 2 172 participants

A Study of Prexasertib (LY2606368) in Platinum-Resistant or Refractory Recurrent Ovarian Cancer

Eli Lilly and Company

NCT03414047

COMPLETED NA 171 participants

Acupressure for Fatigue in Ovarian Cancer Survivors

University of Michigan Rogel Cancer Center

NCT03763838

COMPLETED Phase 3 170 participants

Methods in Education for Breast Cancer Genetics

National Cancer Institute (NCI)

NCT00001806

COMPLETED 169 participants

How Our Immune System Can Help Fight Cancer

Winthrop University Hospital

NCT01042847

COMPLETED Phase 1 152 participants

A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)

Astellas Pharma

NCT00889382

COMPLETED Phase 1 149 participants

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

Incyte Corporation

NCT03314935

COMPLETED Phase 2 148 participants

A Randomized Study of Safety and Efficacy of Pazopanib and Gemcitabine in Persistent or Relapsed Ovarian Cancer

Linda R Duska

NCT01610206

COMPLETED Phase 2 146 participants

Standard Infusion Carboplatin Versus Prophylactic Extended Infusion Carboplatin in Patients With Patients With Recurrent, Ovary, Fallopian Tube, and Primary Peritoneal Cancer

Memorial Sloan Kettering Cancer Center

NCT01248962

COMPLETED Phase 2 132 participants

TEACO: Taxotere, Eloxatin, Avastin in Cancer of the Ovary

Sanofi

NCT00296816

COMPLETED Phase 2 127 participants

Effect of Flutamide on Biomarkers in Blood and Tissue Samples From Patients at High Risk of Ovarian Cancer

University of Arizona

NCT00699907

COMPLETED 125 participants

Feasibility of Multi-gene Panel Testing at the Time of Diagnosis for Patients With Ovarian Cancer

NYU Langone Health

NCT03656809

COMPLETED Phase 2 124 participants

Phase II ABT-888 With Cyclophosphamide

National Cancer Institute (NCI)

NCT01306032

COMPLETED 121 participants

Prevalence+Significance of Paraneoplastic Autoantibodies in Many Cancers

Memorial Sloan Kettering Cancer Center

NCT00608452

COMPLETED Phase 1 107 participants

Safety of BKM120 Monotherapy in Advanced Solid Tumor Patients

Novartis Pharmaceuticals

NCT01068483

COMPLETED Phase 1 103 participants

AMG386 Comb w. Either Pegylated Liposomal Doxorubicin or Topotecan Subjects w. Advanced Recurrent Epithelial Ovarian CR

Amgen

NCT00770536

COMPLETED Phase 2 82 participants

Gemcitabine, Docetaxel, and Filgrastim in Treating Patients With Recurrent or Persistent Leiomyosarcoma or Soft Tissue Sarcoma

Memorial Sloan Kettering Cancer Center

NCT00004066

COMPLETED Phase 2 80 participants

Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer

University of California, San Francisco

NCT00003072

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Phase Distribution

PhaseTrial count
Phase 1 143
Phase 2 87
Phase 3 25
Phase 4 3

Named interventions

Most-linked intervention names on Ovarian Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Bevacizumab Drug
19 trials
Paclitaxel Drug
18 trials
Carboplatin Drug
13 trials
paclitaxel Drug
12 trials
carboplatin Drug
10 trials
Cyclophosphamide Drug
10 trials
Fludarabine Drug
8 trials
Pembrolizumab Drug
8 trials

US sites by state

Facility locations filed on Ovarian Cancer trials. A trial with sites in several states counts in each.

New York 114 trials
California 105 trials
Texas 104 trials
Florida 86 trials
Massachusetts 74 trials
Pennsylvania 58 trials
Michigan 51 trials
Ohio 50 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Ovarian Cancer page

338 registered trials, 147 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Ovarian Cancer condition card totals 338 registered trials; most-linked intervention Bevacizumab; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.